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Droxicam

Product Name
Droxicam
CAS No.
90101-16-9
Chemical Name
Droxicam
Synonyms
E-318;E-3128;Droxar;Ombolan;Dobenam;DROXICAM;Droxicamum;Droxicam USP/EP/BP;5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione;5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
CBNumber
CB0664772
Molecular Formula
C16H11N3O5S
Formula Weight
357.34
MOL File
90101-16-9.mol
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Droxicam Property

Melting point:
259-261°
Boiling point:
554.7±60.0 °C(Predicted)
Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
pka
3.80±0.19(Predicted)
form 
Solid
color 
Off-White to Pale Yellow
CAS DataBase Reference
90101-16-9
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Safety

Toxicity
LD50 orally in male, female mice, and male, female rats: 6192, 8841, 1434, 1994 mg/kg (Soler, 1986)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D689880
Product name
Droxicam
Packaging
500mg
Price
$150
Updated
2021/12/16
TRC
Product number
D689880
Product name
Droxicam
Packaging
5g
Price
$1190
Updated
2021/12/16
Matrix Scientific
Product number
119986
Product name
5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
Purity
95+%
Packaging
1g
Price
$1350
Updated
2021/12/16
Matrix Scientific
Product number
119986
Product name
5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
Purity
95+%
Packaging
250mg
Price
$540
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
57693
Product name
Droxicam
Packaging
1g
Price
$650
Updated
2021/12/16
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Droxicam Chemical Properties,Usage,Production

Description

Droxicam is an orally-active prodrug of piroxicam useful in the treatment of spinal osteoarthritis. Although it has a pharmacological profile comparable to piroxicam, droxicam's experimental ulcerogenic effect is ten times less. In animal studies droxicam is also reported to have analgesic and antipyretic activities, with no cardiovascular or respiratory effects.

Originator

Esteve (Spain)

Uses

Droxicam is a non-steroidal anti-inflammatory drug.

Definition

ChEBI: An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respe tively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis.

brand name

Ombolan

World Health Organization (WHO)

Droxicam is authorized to be marketed in many European countries. Although droxicam is metabolized to piroxicam, it is considered that the risk of hepatic damage differs from that shown by other NSAIDs products, including piroxicam.

Droxicam Preparation Products And Raw materials

Raw materials

Preparation Products

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Droxicam Suppliers

Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Glentham Life Sciences
Tel
--
Fax
--
Email
info@glenthamls.com
Country
United Kingdom
ProdList
1429
Advantage
0
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
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View Lastest Price from Droxicam manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Droxicam 90101-16-9
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
Dideu Industries Group Limited
Product
Droxicam 90101-16-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-15

90101-16-9, DroxicamRelated Search:


  • DROXICAM
  • 5-Methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
  • 5-Methyl-3-(pyridin-2-yl)-2H,5H-1,3-oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide
  • E-318
  • 5-Methyl-3-(2-pyridinyl)-2H,5 H-1,3-oxaZino[5,6-c][1,2]benzothiazine-2,4(3H)-dione-6,6-dioxide
  • Dobenam
  • Droxar
  • E-3128
  • Ombolan
  • 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxide
  • 5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino-[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-diox
  • 5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
  • 2H,5H-1,3-Oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione, 5-methyl-3-(2-pyridinyl)-, 6,6-dioxide
  • Droxicam USP/EP/BP
  • Droxicamum
  • 5-Methyl-3-(pyridin-2-yl)-3-hydro-2H,5H-benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4-dione 6,6-dioxide
  • 90101-16-9
  • C16H11N3O5S