ChemicalBook > CAS DataBase List > (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate

Application

Product Name: (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
CAS No.: 149198-47-0
Chemical Name: (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate
Synonyms: DOCETAXEL SIDE CHAIN NO 2;(3R,4S)-1-Azetidinecarboxylic;（3R,4S)-3triethylsilanyloxy-4-pheny-N-Boc-2-azetidinone;(3R,4S)-3-triethylsilanyloxy-4-phenyl-N-Boc-2-azetidinone;(3R ,4S )-N -BOC-4-phenyl-3-(triethylsilyloxy)-azetidinone;(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone;(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone;(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetid...;(3R,4S)-1-t-butoxycarbonyl-3-triethylsilyloxy-4-phenyl-2-azetidinone;(3R,4S)-1-TERT-BUTOXYCARBONYL-3-TRIETHYLSILYLOXY-4-PHENYL-2-AZETIDINONE
CBNumber: CB0697550
Molecular Formula: C20H31NO4Si
Formula Weight: 377.55
MOL File: 149198-47-0.mol

Less

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate Property

Boiling point:: 463.1±45.0 °C(Predicted)
Density: 1.07
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Oil
pka: -4.79±0.60(Predicted)
color: Colourless
Stability:: Moisture Sensitive
InChI: InChI=1S/C20H31NO4Si/c1-7-26(8-2,9-3)25-17-16(15-13-11-10-12-14-15)21(18(17)22)19(23)24-20(4,5)6/h10-14,16-17H,7-9H2,1-6H3/t16-,17+/m0/s1
InChIKey: LHTDXUKSFSMGCA-DLBZAZTESA-N
SMILES: N1(C(OC(C)(C)C)=O)[C@@H](C2=CC=CC=C2)[C@@H](O[Si](CC)(CC)CC)C1=O
CAS DataBase Reference: 149198-47-0(CAS DataBase Reference)

Less

Safety

HS Code: 2933.79.1500

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TCI Chemical

Product number: B5715
Product name: tert-Butyl (3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylate
Purity: >97.0%(HPLC)
Packaging: 1g
Price: $161
Updated: 2025/07/31

TRC

Product number: B671500
Product name: (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone
Packaging: 50mg
Price: $140
Updated: 2021/12/16

TRC

Product number: B671500
Product name: (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone
Packaging: 500mg
Price: $1110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18884
Product name: (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone
Packaging: 25mg
Price: $140
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18884
Product name: (3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone
Packaging: 50mg
Price: $254.5
Updated: 2021/12/16

Less

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate Chemical Properties,Usage,Production

Application

(3R,4S)-3-(triethylsiloxy)-4-phenyl-2-oxo-azacyclobut-1-carboxylic acid tert-butyl ester is an organic synthesis intermediate and a pharmaceutical intermediate that can be used in laboratory research and development processes as well as in chemical and pharmaceutical synthesis processes.

Chemical Properties

Syrup

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate Suppliers

Americas 1 Canada 1 China 133 Europe 3 Germany 1 India 3 Japan 1 United Kingdom 2 United States 14 Global 159

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Shanghai Bioman Pharma Limited

Tel: 21-33738120 15000110506
Fax: 021-23025272
Email: info@bioman.com.cn
Country: China
ProdList: 61
Advantage: 62

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-83725681-603
Fax: +86 755 28094224
Country: China
ProdList: 4496
Advantage: 50

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Beijing Universal Century Technology Co., Ltd.

Tel: 400-8706899
Fax: 400-8706899
Email: hysj_bj.com
Country: China
ProdList: 3583
Advantage: 55

Shanghai Meishui Chemical Technology Co., Ltd

Tel: 021-60549325 18616193163
Fax: 021-33250306
Country: China
ProdList: 4526
Advantage: 56

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Suzhou Huihe Pharmaceutical Co. Ltd.

Tel: 86-0512-88819360,88985990
Fax: 86-0512-86876095
Email: asynderm@163.com
Country: China
ProdList: 90
Advantage: 60

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 2081
Advantage: 55

Shanghai Shanyuan pharmaceutical technology co., LTD

Tel: 021-31761238 13167072949
Fax: 021-31761238
Email: 3146446224@qq.com
Country: China
ProdList: 1379
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
ProdList: 2267
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 10000
Advantage: 55

Wuhan HongxinKang Fine Chemical Co., Ltd.

Tel: 027-59362599 18674037007
Fax: 027-84802889
Email: zhuoxingwc@163.com
Country: China
ProdList: 950
Advantage: 58

Mirro Chemical Co.,Ltd.

Tel: 0086-15313090952
Fax: 0086-010-80236392
Country: China
ProdList: 2355
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai finete Pharmaceutical Co., Ltd.

Tel: 021-021-00000000 18221039705
Fax: QQ:17263424
Email: finetechpharm@126.com
Country: China
ProdList: 214
Advantage: 58

Zhaoqing Wanwei New Material Technology Co., Ltd.

Tel: 0755-1328880-4488 13068786899
Fax: 13068786899
Email: 13288804488@163.com
Country: China
ProdList: 625
Advantage: 58

Chengdu AiQun Pharmaceutical Technology Co., Ltd.

Tel: 028-82393420 18108156287
Fax: 028-82393420
Email: 2982653826@qq.com
Country: China
ProdList: 560
Advantage: 58

Shanghai Genriver Pharmaceutical Co., Ltd.

Tel: 21-13482015261-883 13482015261
Fax: +86-21-37782903
Email: info@genriverpharm.com
Country: China
ProdList: 444
Advantage: 58

Wuhan Boye Technology Development Co., Ltd.

Tel: 027-81625225 15377010747
Fax: 027-81625225
Email: hui@boyechemicals.com
Country: China
ProdList: 495
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

TCI Chemicals

Tel: 021-67121386, 800-988-0390
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 5391
Advantage: 58

Taizhou Crene Biotechnology Co. Ltd.

Tel: +86-0576-88813233 +86-13396860566
Email: sales@pharm-intermediates.com
Country: China
ProdList: 1991
Advantage: 58

Aishilun biotechnology (Shanghai) co., LTD

Tel: 021-50676523 18019098996
Email: info@acelybio.com
Country: China
ProdList: 3960
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10237
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Zhuoer Chemical Co., Ltd

Tel: 02120970332; +8613524231522
Fax: +86-21-58816016
Email: sales@zhuoerchem.com
Country: China
ProdList: 2904
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Baoji Guokang Healthchem co.,ltd

Tel: +8615604608665 15604608665
Email: dominicguo@gk-bio.com
Country: CHINA
ProdList: 9414
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15109
Advantage: 58

HONG KONG IPURE BIOLOGY CO.,LIMITED

Tel: 86 18062405514 18062405514
Email: ada@ipurechemical.com
Country: CHINA
ProdList: 3461
Advantage: 58

Longyan Tianhua Biological Technology Co., Ltd

Tel: 0086 18039857276 18039857276
Country: CHINA
ProdList: 2783
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Heilongjiang runte Pharmaceutical Co., Ltd

Tel: 13812081281
Email: 13812081281@163.com
Country: China
ProdList: 68
Advantage: 58

Wuhan kemike Biomedical Technology Co., Ltd

Tel: 027-13163388153 13163388153
Email: yeqiu416@163.com
Country: China
ProdList: 9810
Advantage: 58

Less

View Lastest Price from (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate manufacturers

Wuhan ShuEr Biology Technology Co.,Ltd

Product: (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate 149198-47-0
Price: US $20.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 10000kg
Release date: 2022-09-16

Longyan Tianhua Biological Technology Co., Ltd

Product: (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate 149198-47-0
Price: US $150.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000 KG
Release date: 2020-10-26

Career Henan Chemical Co

Product: (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate 149198-47-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-05-25

149198-47-0, (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylateRelated Search:

tert-Butyl acetate Phenyl salicylate 1,4-Dioxane Buprofezin tert-Butanol tert-Butyl peroxyacetate PHENYL VALERATE Ethyltriphenylphosphonium bromide Diphenyl ether Folic acid Cyhalofop-butyl Ascoric Acid PHENYL RESIN 1-N-Boc-3-hydroxyazetidine 1-tert-Butylazetidin-3-ol (3R,4S)-3-Hydroxy-4-phenyl-2-azetidinone ETHOXYTRIETHYLSILANE Docetaxel

2-oxo-4-phenyl-3-triethylsilyloxy-1-azetidinecarboxylic acid tert-butyl ester

DOCETAXEL SIDE CHAIN NO 2

(3R,4S)-TERT-BUTYL 2-OXO-4-PHENYL-3-(TRIETHYLSILYLOXY)AZETIDINE-1-CARBOXYLATE

(3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic acid 1,1-dimethylethyl ester

(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azatidinone

(3R-cis)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1-azetidinecarboxylic Acid 1,1-Dimethylethyl Ester

(3r,4s)-1-Azetidine Carboxylic Acid-2-Oxo-4-Phenyl-3-[(Triethylsilyl)Oxy]-1,1-Dimethyl Ethyl Ester

(3R,4S)-1-AZETIDINECARBOXYLIC ACID 2-OXO-4-PHENYL-3-[(TRIETHYLSILY)OXY]-1,1-DIMETHYLETHYL ESTER

(3R,4S)-1-Azetidinecarboxylicacid-2-Oxo-4-Phenyl-3-[(Triethylsily)Oxy]-1,1-DimethylethylEsterCasNo.

(3R,4S)-1-TERT-BUTOXYCARBONYL-3-TRIETHYLSILYLOXY-4-PHENYL-2-AZETIDINONE

(3R,4S)-1-Azetidinecarboxylic

(3R,4S)-1-t-butoxycarbonyl-3-triethylsilyloxy-4-phenyl-2-azetidinone

(3R-cis)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]-1- azetidinecarboxylic Acid 1,1-DiMethylethyl Es

(3R,4S)-1-t-Boc-3-[(triethylsilyl)oxy]-4-phenyl-2-azetidinone

tert-Butyl (3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylate

(3R,4S)-3-triethylsilanyloxy-4-phenyl-N-Boc-2-azetidinone

(3R ,4S )-N -BOC-4-phenyl-3-(triethylsilyloxy)-azetidinone

1-Azetidinecarboxylic acid, 2-oxo-4-phenyl-3-[(triethylsilyl)oxy]-, 1,1-dimethylethyl ester, (3R,4S)-

(3R,4S)-2-Oxo-4-phenyl-3-[(triethylsilyl)oxy]azetidine-1-carboxylic Acid tert-Butyl Ester

（3R,4S)-3triethylsilanyloxy-4-pheny-N-Boc-2-azetidinone

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetid...

(3R, 4S) -3- (triethylsiloxy) -4-phenyl-2-oxo-azacyclobutan-1-carboxylate tert butyl ester

(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate - [B89557]

149198-47-0

C20H31NO4Si

CHIRAL CHEMICALS

Intermediates

Ketone

Chiral Reagents

Heterocycles