Curcumol

ChemicalBook > CAS DataBase List > Curcumol

Product Name: Curcumol
CAS No.: 4871-97-0
Chemical Name: Curcumol
Synonyms: Curcumo;CURCUMOL;Curcumae;(-)-Curcumol;Curcumol USP/EP/BP;5,8-Epoxy-10(14)-guaien-8-ol;(3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol;(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol;6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-;(3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol
CBNumber: CB0701727
Molecular Formula: C15H24O2
Formula Weight: 236.35
MOL File: 4871-97-0.mol

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Curcumol Property

Melting point:: 141.0 to 145.0 °C
Boiling point:: 334.5±42.0 °C(Predicted)
Density: 1.06±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: DMSO:55.67(Max Conc. mg/mL);235.54(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);84.62(Max Conc. mM)
Ethanol:28.5(Max Conc. mg/mL);120.58(Max Conc. mM)
pka: 13.02±0.60(Predicted)
color: White to Light yellow
InChIKey: QRMPRVXWPCLVNI-YYFQZIEXSA-N
LogP: 3.276 (est)
CAS DataBase Reference: 4871-97-0

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Safety

WGK Germany: 3
HS Code: 29321900

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 36236
Product name: ( ?)-Curcumol
Purity: analytical standard
Packaging: 10mg
Price: $269
Updated: 2022/05/15

TCI Chemical

Product number: C3439
Product name: Curcumol
Purity: >98.0%(GC)
Packaging: 10mg
Price: $133
Updated: 2024/03/01

TCI Chemical

Product number: C3439
Product name: Curcumol
Purity: >98.0%(GC)
Packaging: 50mg
Price: $401
Updated: 2024/03/01

Cayman Chemical

Product number: 26849
Product name: Curcumol
Packaging: 50mg
Price: $596
Updated: 2024/03/01

Cayman Chemical

Product number: 26849
Product name: Curcumol
Packaging: 100mg
Price: $954
Updated: 2024/03/01

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Curcumol Chemical Properties,Usage,Production

Definition

ChEBI: Curcumol is a sesquiterpenoid.

Biological Activity

Curcumol is a biologically active sesquiterpene with many pharmacological activities such as anticancer, antimicrobial, antifungal, antiviral and anti-inflammatory. It efficiently induces apoptosis in many cancer cells by targeting key signaling pathways such as MAPK/ERK, PI3K/Akt and NF-κB, which are often dysregulated in several cancers.

in vitro

Curcumol ((-)-Curcumol) is the major component extracted from root of Rhizoma Curcumae . Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3. It induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway. It suppresses breast cancer cell metastasis by inhibiting MMP-9 via JNK1/2 and Akt-dependent NF-κB signaling pathways.

Curcumol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Curcumol manufacturers

Hebei Duling International Trade Co. LTD

Product: Curcumol 4871-97-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Ton
Release date: 2022-10-17

Shanghai Standard Technology Co., Ltd.

Product: Curcumol 4871-97-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-01-19

Career Henan Chemical Co

Product: Curcumol 4871-97-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 40%-99%
Supply Ability: 1000kg
Release date: 2018-08-20

4871-97-0, CurcumolRelated Search:

4,4'-Diphenylmethane diisocyanate Mangostin BAVACHIN Ginger extract FRIEDELAN-3BETA-OL Vitexin Kresoxim-methyl Methylene Blue ZEDOARY OIL Methylparaben Bensulfuron methyl Methyl acrylate Methyl Methyl bromide Methylene Chloride CURCUMENOL Curcumol

6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,6R,8aS)-

(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol

CURCUMOL

(3s-(3a,3aa,5a,6a,8ab))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6h-3a,6-epoxyazulen-6-ol

5,8-Epoxy-10(14)-guaien-8-ol

(3S-(3alpha,3Aalpha,5alpha,6alpha,8abeta))-octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3A,6-epoxyazulen-6-ol

Curcumae

Curcumol USP/EP/BP

Curcumo

(-)-Curcumol

(3S,3aS,5S,6R,8aS)-5-Isopropyl-3-methyl-8-methyleneoctahydro-6H-3a,6-epoxyazulen-6-ol

4871-97-0

chemical reagent

Inhibitors

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

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