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THIP HYDROCHLORIDE

Product Name
THIP HYDROCHLORIDE
CAS No.
64603-91-4
Chemical Name
THIP HYDROCHLORIDE
Synonyms
THPO;THIP;gaboxadol;Lu 02-030;Gaboxadolum;Gaboxadol-d4;Einecs 264-963-0;THIP HYDROCHLORIDE;Gaboxadolum [latin];4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol
CBNumber
CB0712787
Molecular Formula
C6H8N2O2
Formula Weight
140.14
MOL File
64603-91-4.mol
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THIP HYDROCHLORIDE Property

Melting point:
242-244° (dec)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
ethanol: 0.91 mg/mL
pka
pKa (water, 25°): 4.44 ±0.03; 8.48 ±0.04
form 
solid
color 
white
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NY3396800
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
0807
Product name
THIPhydrochloride
Purity
≥98%(HPLC)
Packaging
50
Price
$162
Updated
2021/12/16
Usbiological
Product number
256926
Product name
THIP hydrochloride
Packaging
50mg
Price
$403
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0001097
Product name
GABOXADOL
Purity
95.00%
Packaging
50MG
Price
$685.21
Updated
2021/12/16
Biorbyt Ltd
Product number
orb528193
Product name
THPO
Packaging
10μg
Price
$290.7
Updated
2021/12/16
ChemScene
Product number
CS-0002507
Product name
THIP
Purity
99.36%
Packaging
25mg
Price
$90
Updated
2021/12/16
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THIP HYDROCHLORIDE Chemical Properties,Usage,Production

Description

Gaboxadol HCl (64603-91-4) is a GABA-A receptor agonist. Hypnotic agent.

Uses

GABAa agonist, GABAc antagonist

Definition

ChEBI: 4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol is an oxazole.

Biological Activity

Systemically active GABA A receptor agonist and GABA C receptor antagonist. Displays antinociceptive, anticonvulsant and sedative effects. Hypnotic agent that enhances delta activity within non-REM sleep in rats.

References

1) Meera et al. (2011), Molecular basis for the high THIP/gaboxadol sensitivity of extrasynaptic GABA(A) receptors; J. Neurophysiol., 106 2057

THIP HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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THIP HYDROCHLORIDE Suppliers

LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Focus Biomolecules
Tel
--
Fax
--
Email
sales@focusbiomolecules.com
Country
United States
ProdList
1284
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
AfferChem, Inc.
Tel
--
Fax
--
Country
United States
ProdList
278
Advantage
0
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
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View Lastest Price from THIP HYDROCHLORIDE manufacturers

Dorne Chemical Technology co. LTD
Product
THIP HYDROCHLORIDE 64603-91-4
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Wuhan Circle Star Chem-medical Technology Co.,Ltd
Product
THIP HYDROCHLORIDE 64603-91-4
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98
Supply Ability
1000
Release date
2025-01-06
Shandong Hanjiang Chemical Co., Ltd
Product
THIP HYDROCHLORIDE 64603-91-4
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-25

64603-91-4, THIP HYDROCHLORIDERelated Search:


  • THIP HYDROCHLORIDE
  • 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3(2h)-onehydrate
  • 4-c)pyridin-3(2h)-one,4,5,6,7-tetrahydro-isoxazolo(hydrate
  • gaboxadol
  • 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL
  • 4,5,6,7-TETRAHYDROISOXAZOLO[5,4-C]PYRIDIN-3-OL HYDROCHLORIDE
  • 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one
  • THIP
  • THPO
  • 4,5,6,7-Tetrahydroisoxazole(5,4-C)pyridin-3-ol
  • Einecs 264-963-0
  • Gaboxadolum
  • Gaboxadolum [latin]
  • Isoxazolo(5,4-C)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
  • Lu 02-030
  • 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one hydrochloride
  • Recombinant Mouse Thrombopoietin/Tpo/Thpo Protein, His Tag
  • Gaboxadol-d4
  • neurons,GABA Receptor,γ-Aminobutyric acid Receptor,IPSCs,THIP,Gamma-aminobutyric acid Receptor,inhibit,sleep disorders,Inhibitor
  • 64603-91-4
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • GABA and Glycine Receptor Modulators
  • Ligand-Gated Ion Channels
  • Ion Channels
  • GABA/Glycine receptor