ChemicalBook > CAS DataBase List > Amyloid β-Protein (1-42) (mouse, rat)

Amyloid β-Protein (1-42) (mouse, rat)

Product Name: Amyloid β-Protein (1-42) (mouse, rat)
CAS No.: 166090-74-0
Chemical Name: Amyloid β-Protein (1-42) (mouse, rat)
Synonyms: BETA-AMYLOID (1-42);DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA;DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA;BAP 1-42;A-BETA(1-42);BETA-AMYLOID (1-40), RAT;Beta-Amyloid (1-42), Rat;BETA-AMYLOID, SODIUM SALT;Rat amyloid-β peptide 1-42;AMYLOID BETA-PROTEIN (1-42)
CBNumber: CB0716336
Molecular Formula: C203H311N55O60S
Formula Weight: 0
MOL File: Mol file

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Amyloid β-Protein (1-42) (mouse, rat) Property

storage temp.: −20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white
Sequence: Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PP69
Product name: β-Amyloid Peptide (1-42), Human
Packaging: .25 mg
Price: $402
Updated: 2025/07/31

Tocris

Product number: 2425
Product name: Amyloidbeta-peptide(1-42)(rat)
Packaging: 500U
Price: $375
Updated: 2021/12/16

Usbiological

Product number: A2275-74F
Product name: β-Amyloid, 1-42
Packaging: 1mg
Price: $303
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109673
Product name: Amyloid b-Protein (1-42) (mouse, rat)
Packaging: 500ug
Price: $315
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109673
Product name: Amyloid b-Protein (1-42) (mouse, rat)
Packaging: 100ug
Price: $91
Updated: 2021/12/16

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Amyloid β-Protein (1-42) (mouse, rat) Chemical Properties,Usage,Production

Uses

Substrate Cleavage Assays (30-100 μg/ml)

Biological Activity

Amyloid beta-peptide (1-42) (rat) is a 42 amino acid polypeptide that is toxic to hippocampal slices and can be used in Alzheimer's disease research.

in vivo

β-Amyloid (1-42), (rat/mouse) can induce Alzheimer's disease^[4].

Induction of Alzheimer's disease^[4]

Background

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder mainly characterized by the abnormal accumulation of β-amyloid (Aβ) peptide. The oligomeric form of the Aβ peptide as being the critical initiator of neurotoxicity in the AD pathogenesis^[4].

Specific Modeling Methods

Rat: Wistar ? male ? adult, weighing 240-260 g
Administration: 1 μg/μL ? Hippocampal injection ? single dose

Note

(1) β-Amyloid (1-42) needs to be processed into oligomers before use.
(2) β-Amyloid (1-42) was injected bilaterally into the hippocampus of rat brain in a volume of 1.0 μL over a period of 0.1 μL/min using 1 μL Hamilton syringe.

Modeling Indicators

Indicator changes: Decreased the gene expression level of α7-nAChR and increased the mRNA expression of NMDA receptor 2A, and -2B subunits.
Behavior: β-Amyloid (1-42) aggregates increased the retention time and altered the behavioral response in rats after 15 days of injection.

Correlated Product(s): β-Amyloid (1-42), (rat/mouse) TFA (HY-P1388A); β-Amyloid (1-40) (rat) (HY-P1387); β-Amyloid (1-40) TFA (HY-P0265A)

Opposite Product(s): /

target

Amyloid-beta

storage

Store at -20°C

Amyloid β-Protein (1-42) (mouse, rat) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Amyloid β-Protein (1-42) (mouse, rat) manufacturers

Career Henan Chemical Co

Product: H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-OH 166090-74-0
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

GenicBio Limited

Product: Beta-Amyloid 1-42 107761-42-2
Price: US $1.00/MG
Min. Order: 1MG
Purity: >95%HPLC
Supply Ability: 1mg,5mg,10mg,25mg,100mg,1g,10g
Release date: 2018-06-11

166090-74-0, Amyloid β-Protein (1-42) (mouse, rat)Related Search:

AMYLOID BETA-PROTEIN (1-15) H-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH H-ILE-ILE-GLY-LEU-MET-OH AMYLOID BETA-PROTEIN (HUMAN, 25-35) TRIFLUOROACETATE H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-OH H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-OH H-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-OH AMYLOID BETA-PROTEIN (29-40) Amyloid β-Peptide (1-42) (human) β-Amyloid Peptide (1-40), rat β-Amyloid Peptide (1-42), Hu 1PC x 0.25M β-Amyloid Peptide (1-42), Ra 1PC x 250UG β-Amyloid Peptide (1-40)

ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA

ASP-ALA-GLU-PHE-GLY-HIS-ASP-SER-GLY-PHE-GLU-VAL-ARG-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA

BAP 1-42

BETA-AMYLOID, SODIUM SALT

Beta-Amyloid Peptide (1-42), mouse, rat

AMyloid b-Protein (1-42) (Mouse, rat)

PREDOMINANT AMYLOID B-PROTEIN FRAGMENT

767: PN: US20090175821 SEQID: 961 claimed protein

Amyloid beta-peptide (1-42) (rat)

Glycopeptide (mouse amyloid A4 peptide)

PN: WO0069900 SEQID: 961 unclaimed protein

Amyloid b-peptide (1-42) (rat)

A-BETA(1-42)

AMYLOID B-PEPTIDE (1-40) (RAT)

AMYLOID BETA-PROTEIN FRAGMENT 1-42

AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)

AMYLOID BETA-PROTEIN (1-42)

AMYLOID-BETA PROTEIN (1-42), HUMAN

AMYLOID BETA-PROTEIN (1-42) HYDROCHLORIDE

AMYLOID BETA-PROTEIN (1-42) (MOUSE, RAT)

H-DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA-OH

BETA-AMYLOID PEPTIDE (1-40), MOUSE, RAT

BETA-AMYLOID PEPTIDE (1-40), RAT

BETA-AMYLOID PEPTIDE (1-42), RAT

BETA-AMYLOID (AA 1-42) PEPTIDE

BETA-AMYLOID, FRAGMENT 1-42

BETA-AMYLOID (1-40), RAT

BETA-AMYLOID (1-42)

BETA-AMYLOID (1-42), N-TERMINAL UNLABELED

BETA-AMYLOID (1-42) PEPTIDE

DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVV

DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA

H2N-D-A-E-F-R-H-D-S-G-Y-F-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A-OH

H2N-D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A-OH

H-ASP-ALA-GLU-PHE-GLY-HIS-ASP-SER-GLY-PHE-GLU-VAL-ARG-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-OH

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-OH

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-OH HYDROCHLORIDE

Amyloid β-peptide (1-42) (rat)

H-ASP-ALA-GLU-PHE-ARG-HIS-ASP-SER-GLY-TYR-GLU-VAL-HIS-HIS-GLN-LYS-LEU-VAL-PHE-PHE-ALA-GLU-ASP-VAL-GLY-SER-ASN-LYS-GLY-ALA-ILE-ILE-GLY-LEU-MET-VAL-GLY-GLY-VAL-VAL-ILE-ALA-OH USP/EP/BP

Rat amyloid-β peptide 1-42

β-Amyloid (1-42),(rat/mouse)

β-Amyloid Peptide (1-42), mouse, rat

β-Amyloid Peptide (1-42), human

Amyloid β-Protein (1-42) (mouse, rat)

β-Amyloid (1-42)， rat (Amyloid β-peptide (1-42) (rat))

β-Amyloid Peptide (1-40), mouse, rat

β-Amyloid 1-42,Rat, ?Amyloid β 1-42,Rat

Amyloid β-peptide (1-42) (rat/mouse) TFA

beta-Amyloid Peptide (1-42) (rat/mouse)

Beta-Amyloid (1-42), Rat

166090-74-0

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Amyloid beta Protein Fragments

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