ChemicalBook > CAS DataBase List > 4-Chloro-2-fluorobenzoic acid

4-Chloro-2-fluorobenzoic acid

Product Name
4-Chloro-2-fluorobenzoic acid
CAS No.
446-30-0
Chemical Name
4-Chloro-2-fluorobenzoic acid
Synonyms
BUTTPARK 19\01-70;TIMTEC-BB SBB003797;RARECHEM AL BO 0755;Furosemide Impurity 30;4-Chloro-2-Fluorobenzoic;4-Chlor-2-fluorbenzoesure;2-FLUORO-4-CHLOROBENZOIC ACID;4-CHLORO-2-FLUOROBENZOIC ACID;4-Chloro-2-fluorobenzoic aicd;4-Chloro-2-fluorobenzoicacid98%
CBNumber
CB0721415
Molecular Formula
C7H4ClFO2
Formula Weight
174.56
MOL File
446-30-0.mol
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4-Chloro-2-fluorobenzoic acid Property

Melting point:
204-208 °C (lit.)
Boiling point:
274.7±20.0 °C(Predicted)
Density 
1.4016 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
3.04±0.10(Predicted)
color 
White to Almost white
Water Solubility 
insoluble
BRN 
973358
InChI
InChI=1S/C7H4ClFO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11)
InChIKey
ZLPXBWMVZANJJQ-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(Cl)C=C1F
CAS DataBase Reference
446-30-0(CAS DataBase Reference)
NIST Chemistry Reference
4-Chloro-2-fluorobenzoic acid(446-30-0)
EPA Substance Registry System
Benzoic acid, 4-chloro-2-fluoro- (446-30-0)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29163990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
436763
Product name
4-Chloro-2-fluorobenzoic acid
Purity
98%
Packaging
5g
Price
$31.7
Updated
2023/06/20
TCI Chemical
Product number
C1668
Product name
4-Chloro-2-fluorobenzoic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$31
Updated
2025/07/31
TCI Chemical
Product number
C1668
Product name
4-Chloro-2-fluorobenzoic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$42
Updated
2025/07/31
TCI Chemical
Product number
C1668
Product name
4-Chloro-2-fluorobenzoic Acid
Purity
>98.0%(T)
Packaging
25g
Price
$126
Updated
2025/07/31
TRC
Product number
C584753
Product name
4-Chloro-2-fluorobenzoic Acid
Packaging
1g
Price
$55
Updated
2021/12/16
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4-Chloro-2-fluorobenzoic acid Chemical Properties,Usage,Production

Chemical Properties

White to light yellow crystal powder

Uses

4-Chloro-2-fluorobenzoic acid may be used in the following studies:

  • As starting reagent for the synthesis of furosemide.
  • Synthesis of 4′-chloro-2′-fluoroacetophenone.
  • Synthesis of novel herbicidal isoxazolecarboxamides.
  • Preparation of potential liquid crystals.

General Description

4-Chloro-2-fluorobenzoic acid is a halogen benzoic acid. It is a non-liquid crystalline carboxylic acid derivative. It has been reported to form hydrogen bonded complexes with benzoylhydrazine-based azobenzene compound. Octanol/water partition coefficient Kow of 4-chloro-2-fluorobenzoic acid has been determined by shake-flask method.

4-Chloro-2-fluorobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-2-fluorobenzoic acid Suppliers

Americas 1 Belgium 1 China 246 Cyprus 1 Europe 4 France 1 Germany 5 India 7 Italy 1 Japan 3 Slovakia 1 Switzerland 2 Ukraine 2 United Kingdom 24 United States 50 Global 349
Fuxin Xin Kaida Fluorine Chemistry Co., Ltd.
Tel
0418-6566789 13464830066
Email
sales@xkdchem.com
Country
China
ProdList
175
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58
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1930
Advantage
55
CHANGZHOU HARVECHEM LTD
Tel
0519-88721112
Fax
0519-88721112
Email
supporting@harvechem.com
Country
China
ProdList
81
Advantage
58
Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
13396369453 QQ3007939906 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
ProdList
906
Advantage
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
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View Lastest Price from 4-Chloro-2-fluorobenzoic acid manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
4-Chloro-2-fluorobenzoic acid 446-30-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-12-10
Speranza Chemical Co., Ltd.
Product
4-Chloro-2-fluorobenzoic acid 446-30-0
Price
US $75.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20 tons
Release date
2019-12-24
Henan Fengda Chemical Co., Ltd
Product
4-Chloro-2-fluorobenzoic acid 446-30-0
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09

446-30-0, 4-Chloro-2-fluorobenzoic acidRelated Search:

(+)-MENTHYL CHLOROFORMATE 3-Chloroperoxybenzoic acid Benzyl chloroformate Phenyl chloroformate Phenyl chlorothionocarbonate Allyl chloroformate 2-Fluorobenzoic acid 4-Fluorobenzoic acid Methyl chloroformate 4-Chloro-5-(chlorosulfonyl)-2-fluorobenzoic acid 4-CHLORO-2-FLUORO-5-NITROBENZOIC ACID Difluorochloromethane t-butyl chloroformate 4,5-DICHLORO-2-FLUOROBENZOIC ACID 5-(Aminosulfonyl)-4-chloro-2-fluorobenzoic acid t-Butyl 4-chloro-2-fluorobenzoate 4-CHLORO-2,6-DIFLUOROBENZOIC ACID Ethyl chloroformate

  • 4-Chloro-2-Fluorobenzoic
  • 4-Chloro-2-fluorobenzoic acid 98%
  • 4-Chloro-2-fluorobenzoicacid98%
  • Benzoic acid, 4-chloro-2-fluoro-
  • 4-Chloro-2-Fluorobenzoic Acid 2-Fluoro-4-Chlorobenzoic Acid
  • 4-CHLORO-2-FLUOROBENZOIC ACID 98%(HPL&
  • RARECHEM AL BO 0755
  • TIMTEC-BB SBB003797
  • 4-Chloro-2-fluorobenzoic Acid, 97+%
  • 4-CHLORO-2-FLUOROBENZOIC ACID
  • 2-FLUORO-4-CHLOROBENZOIC ACID
  • BUTTPARK 19\01-70
  • 4-Chloro-2-fluorobenzoic Acid &gt
  • 4-Chlor-2-fluorbenzoesure
  • 4-Chloro-2-fluorobenzoic aicd
  • Furosemide Impurity 30
  • 446-30-0
  • C7H4ClFO2
  • Organic Building Blocks
  • Building Blocks
  • C7
  • Carboxylic Acids
  • Carbonyl Compounds
  • Fluorine series
  • Benzoic acid
  • Fluorobenzene
  • API intermediates
  • Acids & Esters
  • Chlorine Compounds
  • Fluorine Compounds
  • C7
  • Carbonyl Compounds
  • Carboxylic Acids
  • blocks
  • Carboxes
  • FluoroCompounds
  • Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts