(1-Methyl-1H-imidazol-2-yl)methanol
- Product Name
- (1-Methyl-1H-imidazol-2-yl)methanol
- CAS No.
- 17334-08-6
- Chemical Name
- (1-Methyl-1H-imidazol-2-yl)methanol
- Synonyms
- RARECHEM AL BD 0638;1-Methyl-1H-Imidazol-2-yl;1-Methyl-1H-iMidazol-2-ol;1-Methylimidazol-2-methanol;1-Methyl-2-imidazolemethanol;(1-Methyl-2-iMidazolyl)Methanol;(1-methylimidazol-2-yl)methanol;Imidazole-2-methanol, 1-methyl-;1-Methyl-1H-imidazole-2-methanol;1-Methyl-2-imidazolemethanol,98%
- CBNumber
- CB0758105
- Molecular Formula
- C5H8N2O
- Formula Weight
- 112.13
- MOL File
- 17334-08-6.mol
(1-Methyl-1H-imidazol-2-yl)methanol Property
- Melting point:
- 116-119°C
- Boiling point:
- 145 °C(Press: 1 Torr)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Solid
- pka
- 13.41±0.10(Predicted)
- color
- White to Almost white
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C5H8N2O/c1-7-3-2-6-5(7)4-8/h2-3,8H,4H2,1H3
- InChIKey
- CDQDMLWGTVLQEE-UHFFFAOYSA-N
- SMILES
- C1(CO)N(C)C=CN=1
- CAS DataBase Reference
- 17334-08-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39-37/39
- HazardClass
- IRRITANT
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H1370
- Product name
- 2-Hydroxymethyl-1-methylimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $62
- Updated
- 2025/07/31
- Product number
- H1370
- Product name
- 2-Hydroxymethyl-1-methylimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $188
- Updated
- 2025/07/31
- Product number
- M320968
- Product name
- (1-Methyl-1H-imidazol-2-yl)methanol
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 043221
- Product name
- (1-Methyl-1H-imidazol-2-yl)methanol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $13
- Updated
- 2021/12/16
- Product number
- OR6426
- Product name
- 2-(Hydroxymethyl)-1-methyl-1H-imidazole
- Purity
- 97%
- Packaging
- 5g
- Price
- $15
- Updated
- 2021/12/16
(1-Methyl-1H-imidazol-2-yl)methanol Chemical Properties,Usage,Production
Uses
1-Methyl-2-imidazolemethanol is used as intermediates.
Definition
ChEBI: (1-Methyl-1H-imidazol-2-yl)methanol is a member of imidazoles.
Synthesis
13750-81-7
17334-08-6
The general procedure for the synthesis of 1-methyl-2-hydroxymethyl-1H-imidazole is as follows: synthesis of (1-methyl-1H-imidazol-2-yl)methanol (BB6): to a solution of 1-methyl-1H-imidazole-2-carboxaldehyde (BB5) (40.5 g, 368 mmol) in methanol (300 mL) was added sodium borohydride (NaBH4) (20.89 g) in batches at 0 °C. . The reaction mixture was slowly warmed to room temperature and stirred for 5 hours. Upon completion of the reaction, the mixture was cooled to 0 °C, water (150 mL) was added and stirring was continued at 0 °C for 30 min. Subsequently, the mixture was concentrated under vacuum at room temperature. The crude product was dissolved in water (150 mL) and extracted with chloroform (4 x 200 mL). The organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4) and concentrated. The residue was stirred with ether (Et2O, 150 mL) and filtered to give a white solid product (BB6) (36 g, 87% yield). Thin layer chromatography (TLC) showed an Rf value of 0.4 (15% methanol/chloroform spread).1H NMR (400 MHz, CDCl3) data: δ 6.89 (1H, apparent double peaks), 6.83 (1H, apparent double peaks), 4.66 (2H, single peak), 3.72 (3H, single peak); Mass Spectrometry (m/z): 113 (MH)+.
References
[1] Tetrahedron, 2000, vol. 56, # 4, p. 645 - 657
[2] Patent: US2012/322722, 2012, A1
[3] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 2, p. 363 - 386
[4] Tetrahedron, 1996, vol. 52, # 48, p. 15171 - 15188
[5] South African Journal of Chemistry, 2012, vol. 65, p. 231 - 238
(1-Methyl-1H-imidazol-2-yl)methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(1-Methyl-1H-imidazol-2-yl)methanol Suppliers
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View Lastest Price from (1-Methyl-1H-imidazol-2-yl)methanol manufacturers
- Product
- (1-Methyl-1H-imidazol-2-yl)methanol 17334-08-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- (1-Methyl-1H-imidazol-2-yl)methanol 17334-08-6
- Price
- US $280.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-01