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BERBERINE CHLORIDE

Product Name
BERBERINE CHLORIDE
CAS No.
141433-60-5
Chemical Name
BERBERINE CHLORIDE
Synonyms
BERBERINE HCL;BBR;BERBERIN HCL;5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE;Berberine chloride hydrate 97%;CI 75160;UMBELLATINE;BERBERINE CHLORIDE;TIMTEC-BB SBB006488;LABOTEST-BB LT00440956
CBNumber
CB0758776
Molecular Formula
C20H20ClNO5
Formula Weight
389.83
MOL File
141433-60-5.mol
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BERBERINE CHLORIDE Property

Melting point:
204-206 °C (dec.)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
Colour Index 
75160
color 
Pale Yellow to Yellow
Water Solubility 
Soluble in water.
Sensitive 
Light Sensitive
Merck 
14,1154
BRN 
3836585
Stability:
Hygroscopic
InChIKey
VKJGBAJNNALVAV-UHFFFAOYSA-M
CAS DataBase Reference
141433-60-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22
WGK Germany 
2
RTECS 
DR9866400
3-10
TSCA 
Yes
HS Code 
29399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
14050
Product name
Berberine chloride hydrate
Purity
technical, ≥90% (AT)
Packaging
10g
Price
$67.7
Updated
2024/03/01
Sigma-Aldrich
Product number
14050
Product name
Berberine chloride hydrate
Purity
technical, ≥90% (AT)
Packaging
50g
Price
$82
Updated
2024/03/01
TCI Chemical
Product number
B0450
Product name
Berberine Chloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
B0450
Product name
Berberine Chloride Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$77
Updated
2024/03/01
Alfa Aesar
Product number
L03807
Product name
Berberine chloride hydrate, 97%, water <17%
Packaging
5g
Price
$28.65
Updated
2024/03/01
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BERBERINE CHLORIDE Chemical Properties,Usage,Production

Description

Berberine chloride occurs together with Neprotine (q.v.) in Berberis insignis Hook, B. umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.). It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.) and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p. 265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p. 213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.). Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the ethylimide, m.p. 90°C.

Uses

Berberine chloride is mainly used to treat gastroenteritis, dysentery and other intestinal infections, conjunctivitis and suppurative otitis media.

General Description

Berberine chloride is an alkaloid with antibiotic properties. Berberine chloride induces reactive oxygen species (ROS) production and inhibits DNA topoisomerase. It has anti-tumor properties.

References

Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944)

BERBERINE CHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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BERBERINE CHLORIDE Suppliers

Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
LEHVOSS UK / Gee Lawson Chemical Division
Tel
--
Fax
--
Email
david.davies@lehvoss.co.uk
Country
United Kingdom
ProdList
892
Advantage
58
Tokyo Chemical Industry UK Ltd.
Tel
--
Fax
--
Email
sales@tci-uk.co.uk
Country
United Kingdom
ProdList
1637
Advantage
50
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
Sequoia Research Products Ltd.
Tel
--
Fax
--
Email
sales@seqchem.com
Country
United Kingdom
ProdList
3113
Advantage
69
Zerenex Molecular Limited
Tel
--
Fax
--
Email
sales@zerenex-molecular.com
Country
United Kingdom
ProdList
6204
Advantage
47
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View Lastest Price from BERBERINE CHLORIDE manufacturers

Jinan Million Pharmaceutical Co., Ltd
Product
BERBERINE CHLORIDE 141433-60-5
Price
US $1.00/ton
Min. Order
21ton
Purity
99.98
Supply Ability
ton
Release date
2025-01-04
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Berberine HCl 141433-60-5
Price
US $150.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2024-12-10
Hebei Chuanghai Biotechnology Co,.LTD
Product
BERBERINE CHLORIDE 141433-60-5
Price
US $10.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
1 ton
Release date
2024-08-21

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