3-Amino-1-diphenylmethylazetidine
- Product Name
- 3-Amino-1-diphenylmethylazetidine
- CAS No.
- 40432-52-8
- Chemical Name
- 3-Amino-1-diphenylmethylazetidine
- Synonyms
- BUTTPARK 92\50-95;3-amino-1-benzhylazetidine;3-Amino-1-(diphenylmethyl...;1-BENZHYDRYLAZETIDIN-3-AMINE;1-BENZHYDRYL-3-AMINOAZETIDINE;3-AMINO-1-BENZHYDRYLAZETIDINE;3-Amino-1-Diphenylmethylazetid;1-BENZHYDRYL-AZETIDIN-3-YLAMINE;1-Benzhydrylazetidin-3-amine 97%;3-AMINO-1-DIPHENYLMETHYLAZETIDINE
- CBNumber
- CB0763219
- Molecular Formula
- C16H18N2
- Formula Weight
- 238.33
- MOL File
- 40432-52-8.mol
3-Amino-1-diphenylmethylazetidine Property
- Melting point:
- 63 °C
- Boiling point:
- 339.2±42.0 °C(Predicted)
- Density
- 1.125±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 8.48±0.20(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- InChI
- InChI=1S/C16H18N2/c17-15-11-18(12-15)16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15-16H,11-12,17H2
- InChIKey
- LYTNNHXGUOKXFI-UHFFFAOYSA-N
- SMILES
- N1(C(C2=CC=CC=C2)C2=CC=CC=C2)CC(N)C1
- CAS DataBase Reference
- 40432-52-8(CAS DataBase Reference)
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- A3283
- Product name
- 3-Amino-1-(diphenylmethyl)azetidine
- Packaging
- 1G
- Price
- $81
- Updated
- 2025/07/31
- Product number
- A3283
- Product name
- 3-Amino-1-(diphenylmethyl)azetidine
- Packaging
- 5G
- Price
- $245
- Updated
- 2025/07/31
- Product number
- B408503
- Product name
- 1-Benzhydrylazetidin-3-amine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR6150
- Product name
- 3-Amino-1-(diphenylmethyl)azetidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $21
- Updated
- 2021/12/16
- Product number
- 3H30-1-H1
- Product name
- 3-Amino-1-(diphenylmethyl)azetidine
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $23
- Updated
- 2021/12/16
3-Amino-1-diphenylmethylazetidine Chemical Properties,Usage,Production
Chemical Properties
White powder
Synthesis
143699-92-7
40432-52-8
The general procedure for the synthesis of 1-(diphenylmethyl)-3-aminoazetidine, using 3-azido-1-(diphenylmethyl)azetidine as a starting material, is as follows:[Reference Example 105]; 3-amino-1-diphenylmethylazetidine; [] A 5% palladium-carbon catalyst (200 mg) was added to 3-azido-1-diphenylmethylazetidine made from Reference Example 104 (630 mg) in a solution of ethyl acetate (12 mL). The reaction mixture was subjected to catalytic hydrogenation for 15 hours under hydrogen atmosphere. Upon completion of the reaction, the catalyst was removed by filtration. Subsequently, the solvent was removed by evaporation under reduced pressure. The resulting residue was purified by silica gel column chromatography (eluent: chloroform-methanol mixed solvent) to afford the target product 1-(diphenylmethyl)-3-aminoazetidine (410 mg, 65% yield). The product was characterized by the following data: 1H-NMR (400 MHz, CDCl3) δ: 1.45 (2H, br), 2.62-2.67 (2H, m), 3.51-3.54 (2H, m), 3.59-3.66 (1H, m), 4.28 (1H, s), 7.16-7.40 (10H, m). lc-MS m/z: 239 (M + H)+.
References
[1] Patent: EP1591443, 2005, A1. Location in patent: Page/Page column 67-68
[2] Chemical and Pharmaceutical Bulletin, 1993, vol. 41, # 1, p. 126 - 131
[3] Patent: US6143750, 2000, A
[4] Patent: US6214832, 2001, B1
[5] Medicinal Chemistry Research, 2013, vol. 22, # 12, p. 5982 - 5989
3-Amino-1-diphenylmethylazetidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Amino-1-diphenylmethylazetidine manufacturers
- Product
- 3-Amino-1-diphenylmethylazetidine 40432-52-8
- Price
- US $101.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-28
- Product
- 3-Amino-1-diphenylmethylazetidine 40432-52-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 3-Amino-1-diphenylmethylazetidine 40432-52-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10