1-Octacosanol

ChemicalBook > CAS DataBase List > 1-Octacosanol

Product Name: 1-Octacosanol
CAS No.: 557-61-9
Chemical Name: 1-Octacosanol
Synonyms: Policosanol;OCTACOSANOL;N-OCTACOSANOL;OCTACOSYL ALCOHOL;Cluytyl alcohol;NSC 10770;NSC 57768;Octanosol;Octacosano;ctacosanol
CBNumber: CB0783336
Molecular Formula: C28H58O
Formula Weight: 410.76
MOL File: 557-61-9.mol

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1-Octacosanol Property

Melting point:: 81-83°C
Boiling point:: 200-250°C
Density: 0.8681 (rough estimate)
refractive index: 1.4559 (estimate)
storage temp.: 2-8°C
solubility: Acetonitrile (Slightly, Heated), Benzene (Slightly, Heated), Chloroform (Slightly, Heated)
pka: 15.20±0.10(Predicted)
form: Crystalline Powder or Flaked Crystals
color: White
Water Solubility: <0.1 g/100 mL at 21.5 ºC
Merck: 14,6744
Stability:: Stable. Light-sensitive. Incompatible with strong oxidizing agents.
LogP: 13.066 (est)
CAS DataBase Reference: 557-61-9(CAS DataBase Reference)
NIST Chemistry Reference: Octacosanol(557-61-9)
EPA Substance Registry System: 1-Octacosanol (557-61-9)

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-37/39-26
WGK Germany: -
HS Code: 29051990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: O3379
Product name: 1-Octacosanol
Purity: ≥99% (GC)
Packaging: 100mg
Price: $203
Updated: 2024/03/01

Sigma-Aldrich

Product number: O3379
Product name: 1-Octacosanol
Purity: ≥99% (GC)
Packaging: 1g
Price: $832
Updated: 2024/03/01

TCI Chemical

Product number: O0199
Product name: 1-Octacosanol
Purity: >93.0%(GC)
Packaging: 100mg
Price: $111
Updated: 2024/03/01

TCI Chemical

Product number: O0199
Product name: 1-Octacosanol
Purity: >93.0%(GC)
Packaging: 1g
Price: $526
Updated: 2024/03/01

Cayman Chemical

Product number: 28010
Product name: 1-Octacosanol
Packaging: 100mg
Price: $54
Updated: 2024/03/01

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1-Octacosanol Chemical Properties,Usage,Production

Chemical Properties

white crystals or powder

Occurrence

Octacosanol is developed from wheat germ, sugar cane, or vegetable waxes.

Uses

A 28-carbon primary fatty alcohol commonly found in the epicuticular waxes of plants. It has shown protective effects against parkonsonism and due to its excellent tolerability and non-toxicity, octacosanol may be a promising agent for PD treatment.

Definition

ChEBI: A long-chain primary fatty alcohol that is octacosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group.

benefits

1-octacosanol is a straight-chain aliphatic 28-carbon primary fatty alcohol used as a nutritional supplement. This high-molecular-weight organic compound is the main component of a natural product wax extracted from plants. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties. It has been studied as a potential therapeutic agent for treating Parkinson's disease.

General Description

White crystalline powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

1-Octacosanol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.

Fire Hazard

Flash point data for 1-Octacosanol are not available; however, 1-Octacosanol is probably combustible.

Synthesis

To a solution of octacos-11-en-1-ol (400 mg, 0.98 mmol) in THF (40 mL), 10% of Pd on charcoal (50 mg) was added and poured into a Parr reactor. The reduction was carried out at 80 ℃ and 35 bar H2 under stirring for 4 h. Similar results were achieved when the reaction was performed in a special US reactor (21.2 kHz) that works under pressure (Danacamerini – Torino); the reaction was carried out at 40 ℃ and 6 bar H2 for 3 h. In both cases, after filtration on a celite pad and evaporation under vacuum, a crude product was purified by flash chromatography using hexane: ethyl acetate 19: 1 as eluent. 1-Octacosanol was obtained as a white powder (358 mg, 89% yield)[1].

Purification Methods

Recrystallise it from large volumes of Me2CO. Sublime it at 200-250o/1mm instead of distilling it. [Beilstein 2 IV 1318.]

References

[1] Giancarlo Cravotto. “Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin.” Natural Product Research 24 5 (2010): 428–39.

1-Octacosanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-Triacontanol

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View Lastest Price from 1-Octacosanol manufacturers

Hebei Longbang Technology Co., Ltd

Product: 1-Octacosanol 557-61-9
Price: US $6.00/kg
Min. Order: 1kg
Purity: More than 99%
Supply Ability: 2000KG/Month
Release date: 2024-05-17

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Octacosanol 557-61-9
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-12-10

Baoji Guokang Bio-Technology Co., Ltd.

Product: 1-Octacosanol 557-61-9
Price: US $420.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1-20mt
Release date: 2021-06-04

557-61-9, 1-Octacosanol Related Search:

1-Hexadecanol 1-Eicosanol Ethyl acetate Levulinic acid Lisinopril Dihydrate Ramipril Enalapril 1-HEXACOSANOL Neosperidin dihydrochalcone D-Pinitol Chrysin 1-Triacontanol flavanol METHYL OCTACOSANOATE NIGERICIN SODIUM SALT HENTRIACONTANOIC ACID POLY(MALEIC ANHYDRIDE-ALT-1-OCTADECENE) TRIACONTYL ACETATE

1-Octacosanol,n-Octacosanol

Octacosano

1-Octacosanol SynonyMs: Policosanol

1-Octacosanol Cluytyl alcohol

1-OCTACOSANOL

OCTACOSYL ALCOHOL

OCTACOSANOL

OCTACOSANOL, 1-

N-OCTACOSANOL

MONTANYL ALCOHOL

Twenty-eight alkyl alcohol

Nanoactive Policosanol

NanoLiposomal Policosanol

Octacosanol,95%

octacosan-1-ol

1-OCTACOSANOL 93+%

Policosanol90-98%

Octacosanol10-90%

Octacosanol40-70%

OCTACOSANOL,POWDER

OCTACOSANOL, 1-(P)

POLYCOSANOL 60-80%

Cluytyl alcohol

Policosanol

n-Octacosanol 10%~90%

1-Octacosanol,90+%

NSC 10770

NSC 57768

1-Octacosanol&gt

Octanosol

Octacosanol(Policosanol)

Polyconasol

1-Octacosanol (6CI, 7CI, 8CI, 9CI, ACI)

ctacosanol

Vegan Policosanol

POLICOSANOL(C22-C38)

OCTACOSANOL/Montanyl alcohol

1-Octacosanol in isooctane

557-61-9

142583-61-1

C28H28O

CH3CH227OH

C28H58O

Saturated Higher Alcohols

1-Alkanols

Higher Fatty Acids & Higher Alcohols

Fatty Acids

Fatty Alcohols

Monofunctional & 伪,蠅-Bifunctional Alkanes

Monofunctional Alkanes

Saturated fatty acids and derivatives

Lipids

Biochemicals and Reagents

BioChemical

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).