Sirukumab
- Product Name
- Sirukumab
- CAS No.
- 1194585-53-9
- Chemical Name
- Sirukumab
- Synonyms
- Sirukumab;Sirukumab (anti-IL-6);Research Grade Sirukumab;Research Grade Sirukumab(DHC15803)
- CBNumber
- CB08080842
- Formula Weight
- 0
- MOL File
- Mol file
Sirukumab Property
- form
- Liquid
- color
- Colorless to light yellow
Sirukumab Chemical Properties,Usage,Production
Uses
Sirukumab (CNTO-136) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6, preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis[1][2].
References
[1] Brad H Rovin, et al. A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis. Arthritis Rheumatol. 2016 Sep;68(9):2174-83. DOI:10.1002/art.39722
[2] Bartoli F, et al. Sirukumab for the treatment of rheumatoid arthritis: update on sirukumab, 2018[J]. Expert Review of Clinical Immunology, 2018, 14(7): 539-547. DOI:10.1080/1744666X.2018.1487291
Sirukumab Preparation Products And Raw materials
Raw materials
Preparation Products
Sirukumab Suppliers
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58