ChemicalBook > CAS DataBase List > Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

Product Name
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
CAS No.
112889-02-8
Chemical Name
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Synonyms
Raltitrexed Impurity 24;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
CBNumber
CB0855299
Molecular Formula
C15H22N2O5S
Formula Weight
342.41
MOL File
112889-02-8.mol
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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Property

Boiling point:
519.6±50.0 °C(Predicted)
Density 
1.231
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
12.89±0.46(Predicted)
Appearance
Brown to reddish brown Oil
InChI
InChI=1S/C15H22N2O5S/c1-4-21-13(18)9-6-10(15(20)22-5-2)17-14(19)11-7-8-12(16-3)23-11/h7-8,10,16H,4-6,9H2,1-3H3,(H,17,19)/t10-/m0/s1
InChIKey
OIUDYHGOODXYDK-JTQLQIEISA-N
SMILES
C(OCC)(=O)[C@H](CCC(OCC)=O)NC(C1SC(NC)=CC=1)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M285695
Product name
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicAcidDiethylEster
Packaging
500mg
Price
$1595
Updated
2021/12/16
AK Scientific
Product number
V0741
Product name
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicaciddiethylester
Packaging
100mg
Price
$158
Updated
2021/12/16
AK Scientific
Product number
V0741
Product name
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicaciddiethylester
Packaging
1g
Price
$482
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0007149
Product name
DIETHYL-N-[5-METHYLAMINO-2-THENOYL]-L-GLUTAMATE
Purity
98.00%
Packaging
250MG
Price
$882.42
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0007149
Product name
DIETHYL-N-[5-METHYLAMINO-2-THENOYL]-L-GLUTAMATE
Purity
98.00%
Packaging
1G
Price
$1235.85
Updated
2021/12/16
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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemical Properties,Usage,Production

Uses

N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate manufacturers

Nanjing Fred Technology Co., Ltd
Product
(S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate 112889-02-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-26
Longyan Tianhua Biological Technology Co., Ltd
Product
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 112889-02-8
Price
US $120.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99
Supply Ability
999
Release date
2020-11-10
Longyan Tianhua Biological Technology Co., Ltd
Product
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 112889-02-8
Price
US $120.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
99
Supply Ability
999
Release date
2020-11-10

112889-02-8, Diethyl N-[5-methylamino-2-thenoyl]-L-glutamateRelated Search:


  • n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester
  • diethyl n-[5-methylamino-2-thenoyl]-l-glutamate
  • (S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate
  • L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
  • iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate
  • Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP
  • Raltitrexed Impurity 24
  • 112889-02-8
  • Raltitrexed