ChemicalBook > CAS DataBase List > Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
- Product Name
- Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
- CAS No.
- 112889-02-8
- Chemical Name
- Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
- Synonyms
- Raltitrexed Impurity 24;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
- CBNumber
- CB0855299
- Molecular Formula
- C15H22N2O5S
- Formula Weight
- 342.41
- MOL File
- 112889-02-8.mol
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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Property
- Boiling point:
- 519.6±50.0 °C(Predicted)
- Density
- 1.231
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 12.89±0.46(Predicted)
- Appearance
- Brown to reddish brown Oil
- InChI
- InChI=1S/C15H22N2O5S/c1-4-21-13(18)9-6-10(15(20)22-5-2)17-14(19)11-7-8-12(16-3)23-11/h7-8,10,16H,4-6,9H2,1-3H3,(H,17,19)/t10-/m0/s1
- InChIKey
- OIUDYHGOODXYDK-JTQLQIEISA-N
- SMILES
- C(OCC)(=O)[C@H](CCC(OCC)=O)NC(C1SC(NC)=CC=1)=O
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N-Bromosuccinimide Price
TRC
- Product number
- M285695
- Product name
- N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicAcidDiethylEster
- Packaging
- 500mg
- Price
- $1595
- Updated
- 2021/12/16
AK Scientific
- Product number
- V0741
- Product name
- N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicaciddiethylester
- Packaging
- 100mg
- Price
- $158
- Updated
- 2021/12/16
AK Scientific
- Product number
- V0741
- Product name
- N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamicaciddiethylester
- Packaging
- 1g
- Price
- $482
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- AAA0007149
- Product name
- DIETHYL-N-[5-METHYLAMINO-2-THENOYL]-L-GLUTAMATE
- Purity
- 98.00%
- Packaging
- 250MG
- Price
- $882.42
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- AAA0007149
- Product name
- DIETHYL-N-[5-METHYLAMINO-2-THENOYL]-L-GLUTAMATE
- Purity
- 98.00%
- Packaging
- 1G
- Price
- $1235.85
- Updated
- 2021/12/16
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Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Chemical Properties,Usage,Production
Uses
N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate manufacturers
Nanjing Fred Technology Co., Ltd
- Product
- (S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate 112889-02-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
Longyan Tianhua Biological Technology Co., Ltd
- Product
- Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 112889-02-8
- Price
- US $120.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99
- Supply Ability
- 999
- Release date
- 2020-11-10
Longyan Tianhua Biological Technology Co., Ltd
- Product
- Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 112889-02-8
- Price
- US $120.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99
- Supply Ability
- 999
- Release date
- 2020-11-10
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