ChemicalBook > CAS DataBase List > Copper Peptide

Copper Peptide

Product Name
Copper Peptide
CAS No.
49557-75-7
Chemical Name
Copper Peptide
Synonyms
GHK;Ahk-cu;Glycyl-L-Histidyl-L-Lysine;GHK Cu Copper Peptide;Tripeptide-1 Copper;Copper Peptide AHK-Cu;Cu-GHK;Copper peptides;Copper Peptide powder (GHK-cu);GHK2-CU
CBNumber
CB0875341
Molecular Formula
C14H24N6O4
Formula Weight
340.38
MOL File
49557-75-7.mol
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Copper Peptide Property

Melting point:
>144°C (dec.)
Boiling point:
831.0±65.0 °C(Predicted)
Density 
1.324
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Aqueous Acid (Slightly), DMSO (Slightly)
form 
Solid
pka
3.11±0.10(Predicted)
color 
Off-White
Sequence
Copper gly-his-lys
Stability:
Hygroscopic
InChI
InChI=1S/C14H24N6O4/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24)/t10-,11-/m0/s1
InChIKey
MVORZMQFXBLMHM-QWRGUYRKSA-N
SMILES
C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CN
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27168
Product name
GHK
Packaging
5mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
27168
Product name
GHK
Packaging
10mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
27168
Product name
GHK
Packaging
1mg
Price
$32
Updated
2024/03/01
TRC
Product number
G625230
Product name
Glycyl-L-histidyl-L-lysine
Packaging
250mg
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000052
Product name
COPPER TRIPEPTIDE
Purity
95.00%
Packaging
1G
Price
$216.3
Updated
2021/12/16
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Copper Peptide Chemical Properties,Usage,Production

Description

Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.

Uses

Copper Peptide(GHK-Cu) can be used as skin antiaging agents.

Uses

anti-wrikle

Uses

Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.

Definition

ChEBI: A tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence.

Biological Functions

When applied topically, copper peptide works as an antioxidant, promote collagen and elastin production, and soften the appearance of fine lines and wrinkles.

Pharmaceutical Applications

Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu2+ and its complex role in wound healing. The GHK–Cu(II) complex was isolated from human plasma in the 1970s and it was shown to be an activator for wound healing. GHK–Cu(II) has two main functions: as an anti-inflammatory agent to protect the tissue from oxidative damage after the injury, and as an activator for wound healing itself as it activates the tissue remodelling.
The structure of GHK is very similar to that of common drugs used to treat ulcers.
After the initial stages of wound healing are activated, such as blood coagulation and neutrophil invasion, a second stage of wound healing begins, which includes the population of GHK at the wound, which has a high affinity to Cu2+. Mast cells, which are located in the skin, secrete GHK, which accumulates Cu2+ and forms the copper complex GHK–Cu(II) and therefore increases the metal–tripeptide concentration at the wound. First, GHK–Cu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e. cytokine interleukin-1 (IL-1)). Second, GHK–Cu(II) is released into the blood stream and encourages the production of wound macrophages that support the wound repair by removing the damaged tissue and secreting a family of several growth factor proteins. GHK–Cu(II) also hinders fibroblast production of TGF-β-1 and therefore suppresses the scar development. The GHK–Cu(II) complex also stimulates the growth of blood vessels, neurons and elastin, and, in general, supports most processes of wound healing.

Side effects

While Copper Peptide Serum is generally safe to use, you should be aware of potential side effects that may occur. Although rare, some individuals may experience skin irritation or redness after applying the serum. This can be due to sensitivity to the ingredients or an allergic reaction. Another potential side effect of Copper Peptide Serum is increased sensitivity to sunlight. The serum can make your skin more prone to sunburn.

Copper Peptide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Copper Peptide manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Copper Peptide 49557-75-7
Price
US $85.00-850.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-25
Wuhan Cell Pharmaceutical Co., Ltd
Product
GHK-CU(2:1) 49557-75-7
Price
US $120.00-60.00/box
Min. Order
1box
Purity
99%
Supply Ability
1000kit
Release date
2023-09-06
Wuhan Cell Pharmaceutical Co., Ltd
Product
GHK Cu Copper Peptide;GHK-CU;Copper Peptide 49557-75-7
Price
US $9.90/g
Min. Order
1g
Purity
99%
Supply Ability
1000g
Release date
2023-09-11

49557-75-7, Copper PeptideRelated Search:


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  • 49557-75-7