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beta-D-Fructopyranose

Product Name
beta-D-Fructopyranose
CAS No.
7660-25-5
Chemical Name
beta-D-Fructopyranose
Synonyms
Fructopyranose;S(-)-FRUCTOSE;β-D-Fructopyranose;Frutabs;Levungen;Laevoral;Fructosteril;FRUCTOSE HPLC;Fructose powder;Fructose,HPLC≥96%
CBNumber
CB0875684
Molecular Formula
C6H12O6
Formula Weight
180.16
MOL File
7660-25-5.mol
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beta-D-Fructopyranose Property

Melting point:
103°C
Boiling point:
232.96°C (rough estimate)
Density 
1.6000
refractive index 
1.6170 (estimate)
pka
11.52±0.70(Predicted)
form 
Solid
color 
White to off-white
CAS DataBase Reference
7660-25-5
NIST Chemistry Reference
Fructose(7660-25-5)
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Safety

Hazardous Substances Data
7660-25-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ApexBio Technology
Product number
N1503
Product name
Fructose
Packaging
20mg
Price
$25
Updated
2021/12/16
ChemScene
Product number
CS-8113
Product name
Fructose
Purity
≥98.0%
Packaging
500mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-8113
Product name
Fructose
Purity
≥98.0%
Packaging
1g
Price
$60
Updated
2021/12/16
ChemScene
Product number
CS-8113
Product name
Fructose
Purity
≥98.0%
Packaging
5g
Price
$84
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0000796
Product name
BETA-D-(-)-FRUCTOSE
Purity
95.00%
Packaging
100G
Price
$2457.88
Updated
2021/12/16
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beta-D-Fructopyranose Chemical Properties,Usage,Production

Chemical Properties

Fructose is also called levulose or fruit sugar, C6H12O6. It is the sweetest of the common sugars, being from 1.1 to 2.0 times as sweet as sucrose. Fructose is generally found in fruits and honey. An apple is 4% sucrose, 6% fructose, and 1% glucose (by weight). A grape (Vitis labrusca) is about 2% sucrose, 8% fructose, 7% glucose, and 2% maltose (by weight) (Shallenberger).

Uses

Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.

Production Methods

Commercially processed fructose is available as white crystals, soluble in water, alcohol, and ether, with a melting point between 103 and 105 °C (217.4 and 221 °F) (decomposition). Fructose can be derived by the hydrolysis of inulin; by the hydrolysis of beet sugar followed by lime separation; and from cornstarch by enzymic or microbial action.

Definition

ChEBI: Beta-D-fructopyranose is a D-fructopyranose in which the anomeric centre has beta-configuration. It is an enantiomer of a beta-L-fructopyranose.

in vivo

Fructose can be used in animal modeling to create rat models of hyperuricemia and diabetes. In mice fed a 0% Fructose diet, portal vein (0.060±0.006 mM, overall average across all time points) and systemic (0.030±0.003 mM) Fructose concentrations do not change over time after feeding. In contrast, in wild-type mice, the portal vein concentration more than doubles from time (t)=0 to t=1 hour post-feeding (~0.13 mM). Similarly, systemic serum Fructose increases from 0.037 at t=0 to 0.13 mM one hour post-feeding. In the 20% group, fasting (t=0) serum Fructose levels in the portal vein and systemically are similar to the postprandial concentrations in 0% mice, suggesting that baseline Fructose concentrations during fasting are not affected by diet. At the same dietary conditions, time, and sampling site, serum Fructose concentrations in KHK-/- mice are 5 to 100 times higher than in wild-type mice. The mean (across all time points) portal vein and systemic glucose concentrations in mice fed 20% Fructose are approximately 3 (P=0.004) and 2 (P=0.04) mM higher, respectively, compared to mice fed 0% Fructose. Systemic Fructose concentrations in KHK-/- mice fed 20% Fructose are about three times higher than in mice fed glucose, whereas systemic Fructose concentrations in wild-type mice fed Fructose are similar to those fed glucose[2].

Induces high uric acid[3]
Background
Fructose accelerates the synthesis of purines, increases the production of uric acid, reduces the excretion of uric acid by affecting kidney function, and also produces a large amount of reactive oxygen species, leading to oxidative stress, activating inflammatory signaling pathways and promoting uric acid production.
Specific Modeling Methods
Mice: ICR male mice ? 18-22 g
Administration: 30% Fructose in drinking water ? intragastrically ? for six weeks
Note
(1) Mice were placed in a temperature and humidity controlled environment with a 12 h light-dark cycle[3].
(2) Fresh drinking water was replaced every 2 days[3].
(3) 24 h urine volume was collected and recorded[3].
Modeling Indicators
Molecular changes: mouse renal urate transporter 1 (URAT1), glucose transporter 9 (GLUT9) increased protein levels, ATP-binding cassette subfamily G member 2 (ABCG2) and organic anion transporter 1 (OAT1) decreased protein levels, and organic cation transporter 1 (OCT1) and OCT2 were downregulated. Increases protein levels of TLR4 and MyD88 in the kidneys. NLRP3 inflammasome is activated and IL-1β secretion is increased[3].
Tissue changes: Infiltration of inflammatory cells in mouse glomeruli[3].
Metabolic changes: Increase serum uric acid, creatinine, blood urea nitrogen levels, reduce urine uric acid and creatinine levels (FEUA is significantly reduced)[3].
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Induces type 2 diabetes[4]
Background
Fructose's metabolites induce insulin resistance, and the reactive oxygen species produced lead to oxidative stress, activate inflammatory responses and affect the action of insulin. Fructose is rapidly metabolized in the liver, resulting in excess production, leading to obesity and hyperlipidemia.
Specific Modeling Methods
Rat: Male Sprague Dawley rats ? 200-250 g
Administration: 65% fructose ? oral administration ? 8 weeks of feeding
Note
(1) At 3 and 8 weeks, blood was collected from the retroorbital plexus using small capillary tubes and serum was collected for biochemical analysis[4].
Modeling Indicators
Molecular changes: Serum glucose, insulin, triglyceride, uric acid levels and insulin resistance were significantly increased. TBARS in liver tissue increased and GSH levels decreased[4].
Correlated Product(s): /
Opposite Product(s): /

References

[1] Cirillo P, et al. Fructose induces prothrombotic phenotype in human endothelial cells : A new role for "added sugar" in cardio-metabolic risk. J Thromb Thrombolysis. 2015 Nov;40(4):444-51. DOI:10.1007/s11239-015-1243-1
[2] Patel C, et al. Effect of dietary fructose on portal and systemic serum fructose levels in rats and in KHK-/- and GLUT5-/- mice. Am J Physiol Gastrointest Liver Physiol. 2015 Nov 1;309(9):G779-90. DOI:10.1152/ajpgi.00188.2015
[3] Ying Yang, et al. Wuling San protects kidney dysfunction by inhibiting renal TLR4/MyD88 signaling and NLRP3 inflammasome activation in high fructose-induced hyperuricemic mice. J Ethnopharmacol. 2015 Jul 1:169:49-59. DOI:10.1016/j.jep.2015.04.011
[4] Raju Padiya, et al. Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats. Nutr Metab (Lond). 2011 Jul 27:8:53. DOI:10.1186/1743-7075-8-53

beta-D-Fructopyranose Preparation Products And Raw materials

Raw materials

Preparation Products

PALATINOSE SPINOSAD Lactulose D(-)-Fructose Spinosad D
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beta-D-Fructopyranose Suppliers

China 235 Europe 2 India 4 Ukraine 1 United States 13 Global 255
Tu Shan Bengbu Fengyuan Pharmaceutical Co., Ltd.
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0552-2881011,2881001
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sale@bbcats.com
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Guizhou Dida Technology Co., Ltd
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0851-8475-2296 18096062265
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0851-84752205
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646585516@qq.com
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Beijing HwrkChemical Technology Co., Ltd
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010-89508211 18501085097
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010-89508210
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sales.bj@hwrkchemical.com
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Beijing Ouhe Technology Co., Ltd
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010-82967028 13552068683
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+86-10-82967029
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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Sichuan Kulinan Technology Co., Ltd
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400-1166-196 18981987031
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028-84555506 800101999
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cdhxsj@163.com
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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Shenzhen Sungening Bio-Tech Co., Ltd
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+86-0755-89668383
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+86-0755-89594066/4038
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sales@sungening.com
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China
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Hangzhou Yuhao Chemical Technology Co., Ltd
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0571-82693216
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+86-571-82880190
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info@yuhaochemical.com
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Chengdu Ai Keda Chemical Technology Co., Ltd.
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4008-755-333 18080918076
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028-86757656
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800078821@qq.com
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View Lastest Price from beta-D-Fructopyranose manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
beta-D-Fructopyranose 7660-25-5
Price
US $0.00/G
Min. Order
10G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-14
Hebei Chuanghai Biotechnology Co., Ltd
Product
beta-D-Fructopyranose 7660-25-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29
Hebei Mujin Biotechnology Co.,Ltd
Product
beta-D-Fructopyranose 7660-25-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-11-10

7660-25-5, beta-D-FructopyranoseRelated Search:

Tris(hydroxymethyl)nitromethane Lactulose 2,3:4,5-bis-o-(1-methylethylidene)-beta-d-fructopyranose sulfamate Diacetonefructose SEDOHEPTULOSE ANHYDRIDE Levulinic acid D-Fructose-1,6-diphoshate calcium salt CALCIUM LEVULINATE D(-)-Fructose D-Fructose-1,6-diphosphate trisodium salt octahydrate D-FRUCTOSE 6-PHOSPHATE DISODIUM SALT 5-Aminolevulinic acid hydrochloride TETRAHYDRO-2-(2-PROPYNYLOXY)-2H-PYRAN 2,3-Desisopropylidene Topiramate 2,3:4,5-DI-O-ISOPROPYLIDENE-B-D-FRUCTOPYRANOSE-D12 TOPIRAMATE-D12 2-CHLOROETHYL B-D-FRUCTOPYRANOSIDE Hydroxymethyl

  • beta-D-fructopyranose
  • Fructopyranose
  • FRUCTOSE HPLC
  • Fructosteril
  • Frutabs
  • Laevoral
  • Levungen
  • (2R,3S,4R,5R)-2-methyloltetrahydropyran-2,3,4,5-tetrol
  • FRUCTOPYRANOSE,BETA-D-
  • (2R,3S,4R,5R)-2-(Hydroxymethyl)oxane-2,3,4,5-tetrol
  • S(-)-FRUCTOSE
  • Engelite net impurities 25
  • Empagliflozin impurity 69
  • Fructose,HPLC≥96%
  • beta-D-Fructopyranose USP/EP/BP
  • β-D-Fructopyranose
  • 2-(hydroxymethyl) tetrahydro-2H-pyran-2,3,4,5-tetraol
  • BRL 15573 dihydrochloride
  • D-FRUCTOSE(5-D, 95-98%)
  • Fructose powder
  • (2R,3S,4R,5R)-2-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol
  • Fructose, 10 mM in DMSO
  • 7660-25-5
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • Inhibitors
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract