Pygenic acid A

Product Name: Pygenic acid A
CAS No.: 52213-27-1
Chemical Name: Pygenic acid A
Synonyms: Pygenic acid A;PUNICALAGINS A&B(P);3-Epicorosolic acid;2,3-Dihydroxy-12-ursen-28-oic acid;(2α,3α)-2,3-Dihydroxyurs- 12-en-28-oic acid;(2alpha,3alpha)-2,3-Dihydroxy-urs-12-en-28-oic acid;2α,3α-Dihydroxy-19β-methyl-30-noroleana-12-ene-28-oic acid
CBNumber: CB0947158
Molecular Formula: C30H48O4
Formula Weight: 472.7
MOL File: 52213-27-1.mol

More

Less

Pygenic acid A Property

solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: PXT0002837
Product name: PYGENIC ACID A
Purity: 95.00%
Packaging: 5MG
Price: $505.36
Updated: 2021/12/16

Arctom

Product number: CFN98851
Product name: 3-Epicorosolicacid
Purity: ≥98%
Packaging: 5mg
Price: $463
Updated: 2021/12/16

Crysdot

Product number: CD32001117
Product name: 3-Epicorosolicacid
Purity: 95+%
Packaging: 5mg
Price: $730
Updated: 2021/12/16

More

Less

Pygenic acid A Chemical Properties,Usage,Production

Description

3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction. 3-Epicorosolic acid shows both potent α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activities with IC50 values of 30.18 and 4.08 μg/ml respectively. 3. 3-Epicorosolic acid shows mixed type inhibition against PTP1B, while it shows uncompetitive inhibition against α-glucosidase; suggests that it has potential antidiabetic activity. 4. 3-Epicorosolic acid possesses the ability to inhibit the expression of one or more inflammatory genes induced by 12-O-tetradecanoylphorbol-13 acetate in mouse skin, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.

Uses

Pygenic acid A is a natural compound that can be found in Prunella vulgaris. Pygenic acid A induces apoptosis in metastatic breast cancer cells. Pygenic acid A can be used for the research of diabetes, inflammatory diseases, and cancers[1].

target

Immunology & Inflammation related

References

[1] Ga-Eun Lim, et al. Pygenic Acid A (PA) Sensitizes Metastatic Breast Cancer Cells to Anoikis and Inhibits Metastasis In Vivo. Int J Mol Sci. 2020 Nov; 21(22): 8444. DOI:10.3390/ijms21228444

Pygenic acid A Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Pygenic acid A Suppliers

China 47 United Kingdom 2 United States 7 Global 56

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5645
Advantage: 65

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

Shanghai Hekang Biotechnology Co., Ltd.

Tel: 18939837085
Fax: 2880152141(QQ)
Email: youchemicals@gmail.com
Country: China
ProdList: 1839
Advantage: 55

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71615
Advantage: 60

52213-27-1, Pygenic acid ARelated Search:

hydroxygenkwanin beta-Eudesmol alpha-Terpineol beta-Sitosterol Hydroxyecdysone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Cyperone Artemether MOSLOFLAVONE euscaphic acid Pygenic acid A 1B,2A,3A,24-TETRAHYDROXY-12-URSEN-28-OIC ACID 2,3-DIHYDROXY-(2ALPHA,3ALPHA)-URS-12-EN-28-OIC ACID METHYL ESTER 2,3-BIS(ACETYLOXY)-(2ALPHA,3ALPHA)-URS-12-EN-28-OIC ACID 2A,3A,24-TRIHYDROXY-12-URSEN-28-OIC ACID 2,3-BIS(ACETYLOXY)-(2ALPHA,3ALPHA)-URS-12-EN-28-OIC ACID METHYL ESTER

(2alpha,3alpha)-2,3-Dihydroxy-urs-12-en-28-oic acid

Pygenic acid A

2α,3α-Dihydroxy-19β-methyl-30-noroleana-12-ene-28-oic acid

PUNICALAGINS A&B(P)

2,3-Dihydroxy-12-ursen-28-oic acid

3-Epicorosolic acid

(2α,3α)-2,3-Dihydroxyurs- 12-en-28-oic acid

52213-27-1

Pentacyclic Triterpenes