2-Chloro-5-hydroxypyrimidine
- Product Name
- 2-Chloro-5-hydroxypyrimidine
- CAS No.
- 4983-28-2
- Chemical Name
- 2-Chloro-5-hydroxypyrimidine
- Synonyms
- 2-Chloropyrimidin-5-ol;Piribedil Impurity 17;2-Chloro-5-pyrimidinol;5-PyriMidinol,2-chloro-;2-Chloro-5-hydroxypyrimid...;2-Chloro-5-hydroxypyrimidine;2-Chloro-5-hydroxypyrimidine 98%;5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI);2-Chloro-5-hydroxypyrimidine ISO 9001:2015 REACH;TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
- CBNumber
- CB0947875
- Molecular Formula
- C4H3ClN2O
- Formula Weight
- 130.53
- MOL File
- 4983-28-2.mol
2-Chloro-5-hydroxypyrimidine Property
- Melting point:
- 195-196 °C
- Boiling point:
- 328.1±15.0 °C(Predicted)
- Density
- 1.513±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 6.17±0.23(Predicted)
- CAS DataBase Reference
- 4983-28-2(CAS DataBase Reference)
Safety
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- C373980
- Product name
- 2-Chloro-5-hydroxypyrimidine
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- C373980
- Product name
- 2-Chloro-5-hydroxypyrimidine
- Packaging
- 10g
- Price
- $275
- Updated
- 2021/12/16
- Product number
- C373980
- Product name
- 2-Chloro-5-hydroxypyrimidine
- Packaging
- 25g
- Price
- $495
- Updated
- 2021/12/16
- Product number
- CS-W004687
- Product name
- 2-Chloro-5-hydroxypyrimidine
- Purity
- 99.67%
- Packaging
- 100g
- Price
- $491
- Updated
- 2021/12/16
- Product number
- 4H01-5-13
- Product name
- 2-Chloro-5-hydroxypyrimidine
- Packaging
- 25g
- Price
- $300
- Updated
- 2021/12/16
2-Chloro-5-hydroxypyrimidine Chemical Properties,Usage,Production
Uses
2-Chloro-5-hydroxypyrimidine is an intermediate used to synthesize tandospirone derivatives with anxiolytic activities.
Synthesis
2-Chloro-5-methoxypyrimidine (0.46 g, 3.18 mmol) in methylene chloride (10 mL) was treated with 1.0 N boron tribromide (16 mL, 16 mmol) at room temperature. The solution was stirred overnight. After that, the reaction was partitioned between saturated NaHCO3 and DCM. The aqueous layer was extracted with additional DCM. Combined the organic layers and dried (MgSO4), filtered, and concentrated to obtain the crude product. The residue was purified by flash column chromatography on silica gel to give 2-Chloro-5-hydroxypyrimidine.
2-Chloro-5-hydroxypyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-5-hydroxypyrimidine manufacturers
- Product
- 2-Chloro-5-hydroxypyrimidine 4983-28-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-09
- Product
- 2-Chloro-5-hydroxypyrimidine 4983-28-2
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-Chloro-5-hydroxypyrimidine 4983-28-2
- Price
- US $280.00/G
- Min. Order
- 1G
- Purity
- 99%
- Supply Ability
- customise
- Release date
- 2018-08-01