ChemicalBook > CAS DataBase List > 2-Chloro-5-hydroxypyrimidine

2-Chloro-5-hydroxypyrimidine

Product Name
2-Chloro-5-hydroxypyrimidine
CAS No.
4983-28-2
Chemical Name
2-Chloro-5-hydroxypyrimidine
Synonyms
2-Chloropyrimidin-5-ol;Piribedil Impurity 17;2-Chloro-5-pyrimidinol;5-PyriMidinol,2-chloro-;2-Chloro-5-hydroxypyrimid...;2-Chloro-5-hydroxypyrimidine;2-Chloro-5-hydroxypyrimidine 98%;5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI);2-Chloro-5-hydroxypyrimidine ISO 9001:2015 REACH;TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
CBNumber
CB0947875
Molecular Formula
C4H3ClN2O
Formula Weight
130.53
MOL File
4983-28-2.mol
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2-Chloro-5-hydroxypyrimidine Property

Melting point:
195-196 °C
Boiling point:
328.1±15.0 °C(Predicted)
Density 
1.513±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
6.17±0.23(Predicted)
CAS DataBase Reference
4983-28-2(CAS DataBase Reference)
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Safety

HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
1g
Price
$70
Updated
2021/12/16
TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
10g
Price
$275
Updated
2021/12/16
TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
25g
Price
$495
Updated
2021/12/16
Matrix Scientific
Product number
068747
Product name
2-Chloro-5-hydroxypyrimidine
Purity
>95%
Packaging
1g
Price
$15
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
C14002
Product name
2-Chloropyrimidin-5-ol
Packaging
1g
Price
$38
Updated
2021/12/16
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2-Chloro-5-hydroxypyrimidine Chemical Properties,Usage,Production

Uses

2-Chloro-5-hydroxypyrimidine is an intermediate used to synthesize tandospirone derivatives with anxiolytic activities.

Synthesis

2-Chloro-5-methoxypyrimidine (0.46 g, 3.18 mmol) in methylene chloride (10 mL) was treated with 1.0 N boron tribromide (16 mL, 16 mmol) at room temperature. The solution was stirred overnight. After that, the reaction was partitioned between saturated NaHCO3 and DCM. The aqueous layer was extracted with additional DCM. Combined the organic layers and dried (MgSO4), filtered, and concentrated to obtain the crude product. The residue was purified by flash column chromatography on silica gel to give 2-Chloro-5-hydroxypyrimidine.

2-Chloro-5-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-5-hydroxypyrimidine Suppliers

Shanghai ZaiQi Bio-Tech Co., Ltd.
Tel
021-54824098 13817598959
Fax
021-54824069
Email
sales@chemzq.com
Country
China
ProdList
158
Advantage
55
Nanjing webright Pharmaceutical Technology Co., Ltd
Tel
18014498793
Email
1504914633@qq.com
Country
China
ProdList
335
Advantage
58
PharmaBlock Sciences (Nanjing), Inc.
Tel
4000255188
Email
xu_meiqin@pharmablock.com
Country
China
ProdList
9126
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
668
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55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12426
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
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View Lastest Price from 2-Chloro-5-hydroxypyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-19
Dideu Industries Group Limited
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

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