ChemicalBook > CAS DataBase List > 2-Chloro-5-hydroxypyrimidine

2-Chloro-5-hydroxypyrimidine

Product Name
2-Chloro-5-hydroxypyrimidine
CAS No.
4983-28-2
Chemical Name
2-Chloro-5-hydroxypyrimidine
Synonyms
2-Chloropyrimidin-5-ol;Piribedil Impurity 17;2-Chloro-5-pyrimidinol;5-PyriMidinol,2-chloro-;2-Chloro-5-hydroxypyrimid...;2-Chloro-5-hydroxypyrimidine;2-Chloro-5-hydroxypyrimidine 98%;5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI);2-Chloro-5-hydroxypyrimidine ISO 9001：2015 REACH;TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
CBNumber
CB0947875
Molecular Formula
C4H3ClN2O
Formula Weight
130.53
MOL File
4983-28-2.mol
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2-Chloro-5-hydroxypyrimidine Property

Melting point:
195-196 °C
Boiling point:
328.1±15.0 °C(Predicted)
Density 
1.513±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
6.17±0.23(Predicted)
CAS DataBase Reference
4983-28-2(CAS DataBase Reference)
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Safety

HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
1g
Price
$70
Updated
2021/12/16
TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
10g
Price
$275
Updated
2021/12/16
TRC
Product number
C373980
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
25g
Price
$495
Updated
2021/12/16
ChemScene
Product number
CS-W004687
Product name
2-Chloro-5-hydroxypyrimidine
Purity
99.67%
Packaging
100g
Price
$491
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-5-13
Product name
2-Chloro-5-hydroxypyrimidine
Packaging
25g
Price
$300
Updated
2021/12/16
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2-Chloro-5-hydroxypyrimidine Chemical Properties,Usage,Production

Uses

2-Chloro-5-hydroxypyrimidine is an intermediate used to synthesize tandospirone derivatives with anxiolytic activities.

Synthesis

2-Chloro-5-methoxypyrimidine (0.46 g, 3.18 mmol) in methylene chloride (10 mL) was treated with 1.0 N boron tribromide (16 mL, 16 mmol) at room temperature. The solution was stirred overnight. After that, the reaction was partitioned between saturated NaHCO3 and DCM. The aqueous layer was extracted with additional DCM. Combined the organic layers and dried (MgSO4), filtered, and concentrated to obtain the crude product. The residue was purified by flash column chromatography on silica gel to give 2-Chloro-5-hydroxypyrimidine.

2-Chloro-5-hydroxypyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-5-hydroxypyrimidine Suppliers

Austria 1 China 238 Europe 2 Germany 1 India 2 Japan 1 United Kingdom 3 United States 16 Global 264
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from 2-Chloro-5-hydroxypyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50ton
Release date
2020-05-19
Dideu Industries Group Limited
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Chloro-5-hydroxypyrimidine 4983-28-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11

4983-28-2, 2-Chloro-5-hydroxypyrimidineRelated Search:

HYDROXYAPATITE TYPE I Glycolic acid 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL Sulfadiazine 2-Chloropyrimidine Uracil Hydroxy silicone oil Chrysin Silver sulfadiazine 4-Hydroxybenzaldehyde 5-Hydroxypyrimidine 2-Chloro-5-fluoropyrimidine Tandospirone 1-N-Boc-4-pyriMidin-2-yl-piperazine (3aR,4R,7S,7aS)-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]hexahydro-1H-4,7-methanoisoindole-1,3-dione Difluorochloromethane Camptothecin Series--10-hydroxycamptothecin 2,4-Dichloro-5-methoxypyrimidine

  • 2-Chloro-5-hydroxypyrimidine 98%
  • 2-Chloro-5-hydroxypyrimidine
  • 5-Pyrimidinol, 2-chloro- (7CI,8CI,9CI)
  • 2-Chloropyrimidin-5-ol
  • 2-Chloro-5-hydroxypyrimid...
  • 5-PyriMidinol,2-chloro-
  • 2-Chloropyrimidin-5-ol, 2-Chloro-5-hydroxy-1,3-diazine
  • 2-Chloro-5-pyrimidinol
  • 2-Chloro-5-hydroxypyrimidine ISO 9001：2015 REACH
  • Piribedil Impurity 17
  • TIANFU-CHEM 2-Chloro-5-hydroxypyrimidine 4983-28-2
  • 4983-28-2
  • 1983-28-2
  • Heterocycle-Pyrimidine series
  • PYRIMIDINE
  • pharmacetical
  • Pyrimidines