ChemicalBook > CAS DataBase List > Sitagliptin phosphate monohydrate

Sitagliptin phosphate monohydrate

Product Name
Sitagliptin phosphate monohydrate
CAS No.
654671-77-9
Chemical Name
Sitagliptin phosphate monohydrate
Synonyms
Sitagliptin phosphate hydrate;Sitagliptin monohydrate;(R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate;Sitagliptin Phosphate.H2O;(R)-3-Amino-1-(3-(trifluor;itagliptin phosphate monohydrate;(R)-3-AMino-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate hydrate;7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate;7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1) monohydrate;D06645
CBNumber
CB11011754
Molecular Formula
C16H18F6N5O5P
Formula Weight
505.31
MOL File
654671-77-9.mol
More
Less

Sitagliptin phosphate monohydrate Property

Flash point:
274.3℃
storage temp. 
2-8°C
solubility 
≥23.8 mg/mL in DMSO; insoluble in EtOH; ≥30.6 mg/mL in H2O with ultrasonic
form 
solid
color 
White to off-white
InChI
InChI=1/C16H15F6N5O.H3O4P/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22;1-5(2,3)4/h4,6,9H,1-3,5,7,23H2;(H3,1,2,3,4)/t9-;/s3
InChIKey
IQFYVLUXQXSJJN-OVMXBOEKNA-N
SMILES
P(O)(O)(O)=O.C(C1=NN=C2CN(C(=O)C[C@H](N)CC3C=C(F)C(F)=CC=3F)CCN12)(F)(F)F |&1:15,r|
CAS DataBase Reference
654671-77-9(CAS DataBase Reference)
More
Less

Safety

Risk Statements 
28-38-41-48-62-63
Safety Statements 
24/25-26-28-36/37/39
HS Code 
29335990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR1857
Product name
Sitagliptin Phosphate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$173
Updated
2024/03/01
Sigma-Aldrich
Product number
1612903
Product name
Sitagliptin phosphate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$436
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0001812
Product name
Sitagliptin phosphate monohydrate
Purity
EuropePharmacopoeia (EP) Reference Standard
Packaging
y0001812
Price
$220
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0000800
Product name
SITAGLIPTIN PHOSPHATE MONOHYDRATE
Purity
95.00%
Packaging
1G
Price
$918.23
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000800
Product name
SITAGLIPTIN PHOSPHATE MONOHYDRATE
Purity
95.00%
Packaging
5G
Price
$2246.48
Updated
2021/12/16
More
Less

Sitagliptin phosphate monohydrate Chemical Properties,Usage,Production

Chemical Properties

white crystalline

Uses

antimuscarinic

Uses

Sitagliptin Phosphate Monohydrate is a dipeptidyl peptidase-IV (DPPIV) inhibitor.

Biological Activity

sitagliptin phosphate monohydrate is the phosphate salt of its active component, sitagliptin, with one molecule of water. sitagliptin is a potent inhibitor of dipeptidyl peptidase 4 (dpp-4), an enzyme catalyzing the cleavage of peptides with an n-terminal alanine or proline amino acid residue, that selectively inhibits dpp-4 with 50% inhibition concentration ic50 value of 18 nm and shows no affinity towards other ddp enzymes (such as ddp-8 and ddp-9). the inhibition of dpp4 by sitagliptin has been found to be mediated by increasing levels of two dpp-4 substrates, including glucagon-like peptide-1 (glp-1) and gastric inhibitory polypeptide (gip). sitagliptin is currently being investigated in the treatment of type ii diabetes.gallwitz b. review of sitagliptin phosphate: a novel treatment for type 2 diabetes. vasc health risk manag. 2007;3(2):203-10.

target

DPP-4

Sitagliptin phosphate monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Sitagliptin phosphate monohydrate Suppliers

Australia 1 Canada 1 China 459 Germany 1 India 50 South Africa 1 Spain 3 United Kingdom 5 United States 28 Global 549
Hefei HomeSunshine Pharmaceutical Technology Co., Ltd.
Tel
0551-65523315 17705606359
Fax
0551-65523375
Email
errol@homesunshinepharma.com
Country
China
ProdList
71
Advantage
58
Changzhou Kangte Pharmtech Co.,Ltd
Tel
0519-82813797 18994752886
Fax
0519-82813703
Email
czkangte@hotmail.com
Country
China
ProdList
45
Advantage
62
Ningbo Zhenlei Chemical Co.,ltd.
Tel
0576-88808091 13958565781
Fax
+0576-88203603
Email
shuang.lin@zhenleichem.com
Country
China
ProdList
89
Advantage
58
AnHui HaiKang Pharmaceutical Co., Ltd.
Tel
0556-5800026 17709662922
Email
melrose@worldpharma.cn
Country
China
ProdList
247
Advantage
55
Beijing Huikang Boyuan Chemical Tech Co., Ltd
Tel
010-68862197 13810598707
Fax
010-68882204
Email
sales@huikangchem.com
Country
China
ProdList
103
Advantage
61
Zhejiang Jiuzhou Pharmaceutical Co., Ltd
Tel
13566413511
Email
le.sun@jiuzhoupharma.com
Country
China
ProdList
31
Advantage
58
Tiantai Yisheng Biochemical Technology Co., Ltd
Tel
18958639818微信同号尽量微信不要电话
Email
156697457@qq.com
Country
China
ProdList
117
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Scientia Pharmaceutical Technology Co., Ltd.
Tel
21-21-54301573 13917723525
Fax
(86)21-51861981
Email
sales@scientiapharm.com
Country
China
ProdList
263
Advantage
62
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Anhui Lianchuang Biological Medicine Co.,Ltd
Tel
0551-68779238 18056025720
Email
sales3@lcywhx.com
Country
China
ProdList
159
Advantage
57
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
Jinan Trio PharmaTech Co., Ltd.
Tel
+86 (531) 88811783
Fax
+86 (531) 55696010 QQ 1762738062
Email
sales@trio-pharmatech.com (International market)
Country
China
ProdList
1856
Advantage
62
Shanghai Aobo pharmaceutical Technology Co., Ltd
Tel
86-21-51320499
Fax
86-21-51320368
Email
aobo@aobopharm.com
Country
China
ProdList
297
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4552
Advantage
62
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2871
Advantage
58
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4940
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1637
Advantage
59
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9459
Advantage
58
NCE Biomedical Co.,Ltd.
Tel
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
Fax
+86-27-87599188
Country
China
ProdList
1493
Advantage
55
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
China Kouting Group Limited
Tel
+86 (21) 5811-6473 5811-6475
Fax
+86 (21) 6129-4103
Email
sales@koutingchina.com
Country
China
ProdList
496
Advantage
60
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Bsisun HK Imoprt And Export Company Limited
Tel
+86-18068513926
Fax
0086-519-85153711
Country
China
ProdList
1277
Advantage
55
Cantotech Chemicals, Ltd.
Tel
86-0755-86635001
Fax
86-0755-22642228
Email
cantotech@126.com
Country
China
ProdList
4566
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai Chemchallenger Biotech Co., Ltd
Tel
86-021-58568415
Fax
86-021-61606968
Country
China
ProdList
17
Advantage
58
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
860
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185 18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3466
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3120
Advantage
55
Suzhou lipin Chemical Co., Ltd
Tel
0512-0512-67509664 19888480046
Country
China
ProdList
121
Advantage
58
Shanghai Meishui Chemical Technology Co., Ltd
Tel
021-60549325 18616193163
Fax
021-33250306
Country
China
ProdList
4526
Advantage
56
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Eastbang Pharmaceuticals Technology Co., Ltd.
Tel
+86 (20) 28996708,29078958,28139708,29076128,28133708,28139728,28139738,28133718,021-31663278,021-31663578,021-60538387
Fax
+86 (20) 39218032
Country
China
ProdList
454
Advantage
58
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
More
Less

View Lastest Price from Sitagliptin phosphate monohydrate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Sitagliptin phosphate monohydrate 654671-77-9
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%-102;USP
Supply Ability
1000KGS
Release date
2021-07-02
S&Y Biochem Co.,Ltd
Product
Sitagliptin phosphate monohydrate 654671-77-9
Price
US $1.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-08-01
Nanjing Fred Technology Co., Ltd
Product
Sitagliptin phosphate monohydrate 654671-77-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%, Single impurity＜0.1
Supply Ability
1 ton
Release date
2024-01-02

654671-77-9, Sitagliptin phosphate monohydrateRelated Search:

tert-Butylchlorodiphenylsilane Dibutyl phthalate N,N-Dimethyl-1,4-phenylenediamine Sodium Phosphate Monobasic Monohydrate Glycine Buprofezin 2-Methyl-1-propanol Betamethasone 21-phosphate disodium 2-Butoxyethanol Calcium phosphate AMPHISOL A butyl rubber tert-Butyldimethylsilyl chloride BUTYL OLEATE MELIBIOSE Oseltamivir phosphate Tributyl phosphate tert-Butyl methyl ether

  • Sitagliptin monohydrate
  • Sitagliptin Phosphate.H2O
  • Sitagliptin Monophosphate Monohydrate
  • (R)-3-AMino-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate hydrate
  • Sitaglipin Phosphate Monohydrate
  • (R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate
  • (R)-3-Amino-1-(3-(trifluor
  • Sitagliptin posphate monohydrate
  • Sitagliptin phosphate monohydrate, 97%, DPP-IV inhibitor
  • Sitagliptin phosphate monohydrate 99%
  • sitagpliptin monohydrate
  • (2R)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine Dihydrogen Phosphate Monohydrate
  • Sitagliptin phosephate monohydrate
  • MK-0431 PHOSPHATE MONOHYDRATE
  • 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate
  • Sitagliptin phosphate monohydrate 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate monohydrate
  • Sitagliptin phosphate mon
  • Sitagliptin phosphate monohydrate, >=99%
  • 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine phosphate (1:1) monohydrate
  • (R)-3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4
  • Sitagliptin phosphate monohydrate
  • Sitagliptin phosphate for research
  • D06645
  • Januvia (tn)
  • Sitagliptin phosphate (usan)
  • Sitagliptin phosphate hydrate
  • Sitagliptin phosphate hydrate (jan)
  • Sitagliptin phosphate monohydrate CRS
  • Creatinine, Uric acid, Urea, Glucose
  • Siglitatin phosphate
  • 1,2,4-Triazolo[4,3-a]pyrazine,7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-, phosphate (1:1), monohydrate
  • Sitagliptin phosphate monohydrate USP/EP/BP
  • Sitagliptin Phosphate Monohydrate Please see S491000
  • Sitagliptin phosphate monohydrate (API)
  • Manufacturer Supplying High Quality Sitagliptin Phosphate Monohydrate API with CAS 654671-77-9
  • Sitagliptin phosphate (Monohydrate)Q: What is Sitagliptin phosphate (Monohydrate) Q: What is the CAS Number of Sitagliptin phosphate (Monohydrate) Q: What is the storage condition of Sitagliptin phosphate (Monohydrate)
  • Sitagliptin Phosphate (1612903)
  • itagliptin phosphate monohydrate
  • SIT-12
  • (R)-Sitaglipin Phosphate Monohydrate
  • 1-Octen-3-ol 3391-86-4
  • SITAGLIPTIN PHOSAPHATE MONOHYDRATE-IP
  • Sitagliptin Impurity 15 Phosphate Monohydrate
  • Sitagliptin Phosphate Monohydrate-IP /USP/BP
  • Sitagliptin Impurity 20 Phosphate Monohydrate
  • 654671-77-9
  • C16H20F6N5O6P
  • C16H15F6N5OH3PO4H2O
  • C16H15F6N5OH3O4PH2O
  • C16H15F6N5OH2OH3O4P
  • Inhibitors
  • Inhibitor
  • API
  • APIs
  • 654671-77-9