ChemicalBook > CAS DataBase List > 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid

4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid

Product Name
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid
CAS No.
137281-39-1
Chemical Name
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid
Synonyms
4-(2-(2-AMino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl)benzoic acid;Pemetrexed Intermediate Benzoic Acid;4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid;]-benzoic acid;US-DMF No.: 031215;4-[2-(2-Amino-4,7-di;Pemetrexed Impurity 7;PeMetrexed IMpurity A;Pemetrexed Impurity 11;o[2,3-d]pyrimidin-5-yL
CBNumber
CB11012504
Molecular Formula
C15H14N4O3
Formula Weight
298.3
MOL File
137281-39-1.mol
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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Property

Melting point:
>270°C (dec.)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
4.30±0.10(Predicted)
color 
White to Pale Pink
InChI
InChI=1S/C15H14N4O3/c16-15-18-12-11(13(20)19-15)10(7-17-12)6-3-8-1-4-9(5-2-8)14(21)22/h1-2,4-5,7H,3,6H2,(H,21,22)(H4,16,17,18,19,20)
InChIKey
AIZPFZIKHIJCQX-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC=C(CCC2C3C(=O)NC(N)=NC=3NC=2)C=C1
CAS DataBase Reference
137281-39-1(CAS DataBase Reference)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2618
Product name
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$35
Updated
2024/03/01
TCI Chemical
Product number
A2618
Product name
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Hydrate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$137
Updated
2024/03/01
TRC
Product number
A604905
Product name
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoicAcid
Packaging
50mg
Price
$120
Updated
2021/12/16
TRC
Product number
A604905
Product name
4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoicAcid
Packaging
1g
Price
$340
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
APN0002195
Product name
4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)ETHYL]-BENZOIC ACID
Purity
95.00%
Packaging
25MG
Price
$704.55
Updated
2021/12/16
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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Chemical Properties,Usage,Production

Chemical Properties

Pale Pink Solid

Uses

Pemetrexed intermediate

4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid Suppliers

Americas 1 Canada 3 China 297 Europe 1 France 1 Germany 3 India 47 Japan 1 Ukraine 1 United Kingdom 6 United States 30 Global 391
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 137281-39-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-11-09
Hebei Dangtong Import and export Co LTD
Product
4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acid 137281-39-1
Price
US $60.00/kilograms
Min. Order
100kilograms
Purity
99%
Supply Ability
100tons
Release date
2023-03-01
Hangzhou ICH Biofarm Co., Ltd
Product
Pemetrexed disodium INT-4 137281-39-1
Price
US $0.00/kg
Min. Order
1kg
Purity
99.0%min
Supply Ability
5MT
Release date
2023-06-14

137281-39-1, 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-yl)ethyl]benzoic acidRelated Search:

Pemetrexed Disodium Heptahydrate 4-(4-Hydroxybutyl)benzoic acid Methyl ester 3-Buten-1-ol Lithium bis(trimethylsilyl)amide Methyl 4-(4-hydroxybut-1-ynyl)benzoate Pemetrexed Impurity 17 Pemetrexed Impurity 11 2,4-Diamino-6-hydroxypyrimidine Gemcitabine hydrochloride Pemetrexed Disodium Pemetrexed disodium hemipentahydrate 3-Butyn-1-ol N-[4-[2-(2-AMino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoyl]-L-glutaMic Acid Methyl 4-(4-oxobutyl)benzoate N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester 4-[2’-(7’’-Deazaguanine)ethyl]benzoic Acid N-Hydroxysuccinimide Ester N-[4-[3-(2,6-DiaMino-1,4-dihydro-4-oxo-5-pyriMidinyl)-3-oxopropyl]benzoyl]-L-glutaMic Acid PeMetrexed IMpurity D

  • 4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo(2,3-d)pyrimidin-5-yl)ethyl)benzoic acid (intermediate of pemetrexed)
  • 4-[2-(2-AMINO-4,7-DIHYDRO-4-OXO-1H-PYMOL[2,3-D]PYRIMODIN-5-YL)ETHYL]BENZOIC ACID
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-Benzoic Acid
  • 4-[2-（2-Amino-4-oxo-4,7- Dihydro-3H-pyrrolo[2,3-d]pyrimidine -5-yl）ethyl]benzoic acid
  • Pemetrexed reference substance
  • Benzoic acid, 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]- (9CI)
  • Pemetrexed Intermediate Benzoic Acid
  • Pemetrexed acid intermediate
  • 4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)
  • Pemetrexed disodium intermediate
  • Pemetrexed Intermediate
  • 4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid
  • Pemetrexed Impurity 11
  • 4-(2-(2-amino-4,7-dihydro-4-oxo-1h-pyrrol(2,3-d)pyrimidin-5-yl)ethyl)benzoic acid
  • pymol-[2,3-d]pyrimidin-5-yl) ethyl]
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-3<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-5-yl)ethyl]benzoic Acid Hydrate
  • Pemetrexed Impurity 7
  • 4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]benzoic acid ,98%
  • 4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]-benzoic acid ,99%
  • 4-[2-(2-Amino-4,7-di
  • 4-[2-(-AMino-4,7-dihydro-4-oxo-1H-pyMol[2,3-d]pyriModin-5-yl)ethyl]benzoic acid
  • 4-(2-{2-aMino-4-oxo-3H,4H,7H-pyrrolo[2,3-d]pyriMidin-5-yl}ethyl)benzoic acid
  • 4-(2-(2-AMino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl)benzoic acid
  • 4-[2-(2-AMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]benzoic Acid Hydrate
  • d pyriModin -5-yl)ethyl benzoic acid
  • PeMetrexed IMpurity A
  • 4- 2-(2-AMino-4,7-dihydro-4-oxo-1H-pyrrolo 2...
  • PeMetrexed disodiuM INT-4
  • Benzoic acid,4-[2-(2-aMino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyriMidin-5-yl)ethyl]-
  • Pemetrexed Intermediate(PMC)
  • 4[2-(2-amino-4,7-dihydro-4-oxo-1H-pymol [2,3-pyrimodin-5-yl]ethyl) benzoic acid
  • 4-(2-(2-amino-4-oxo-4,7-dihydro-
  • Pemetrexed disodium Impurity 13
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Hydrate&gt
  • 4-[2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrroL
  • o[2,3-d]pyrimidin-5-yL
  • ]-benzoic acid
  • 2-Amino-4,7-dihydro-5-[2-[4-(carboxy)phenyl]ethyl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pymol[2,3-d]pyrimodin-5-y...
  • US-DMF No.: 031215
  • 4 - [2 - (2-amino-4,7-dihydro-4-ox-1H-pyrrole [2,3-D] pyrimidin-5-yl) ethyl] benzoic acid
  • 4-[2-(2-Amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid
  • 4- [2- (2-amino-4,7-dihydro-4-oxo-3H-pyrrolo [2,3] pyrimidin-5-yl) ethyl] benzoic acid
  • 4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Hydrate, ≥ 98.0%
  • 137281-39-1
  • 4-137281-39-1
  • C15H14N4O3xH2O
  • Intermediates
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Organic acids
  • PEMETREXED DISODIUM
  • (intermediate of pemetrexed)
  • Various Intermediates