ChemicalBook > CAS DataBase List > Pralmorelin

Pralmorelin

Product Name
Pralmorelin
CAS No.
158861-67-7
Chemical Name
Pralmorelin
Synonyms
GHRP-2;GHRP;CHRP-2;GHRP-2 ACETATE;GHCA;EIF3A;d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide;-2;-2;p-ERK1
CBNumber
CB1104514
Molecular Formula
C45H55N9O6
Formula Weight
817.97
MOL File
158861-67-7.mol
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Pralmorelin Property

Melting point:
149 - 151°C
Boiling point:
1265.3±65.0 °C(Predicted)
Density 
1.270±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO (Slightly, Sonicated), Water (Slightly)
form 
lyophilized powder
pka
13.40±0.46(Predicted)
color 
white to beige
Stability:
Hygroscopic
InChI
InChI=1S/C45H55N9O6/c1-27(47)41(56)52-38(24-30-19-20-31-14-6-7-15-32(31)22-30)43(58)50-28(2)42(57)53-39(25-33-26-49-35-17-9-8-16-34(33)35)45(60)54-37(23-29-12-4-3-5-13-29)44(59)51-36(40(48)55)18-10-11-21-46/h3-9,12-17,19-20,22,26-28,36-39,49H,10-11,18,21,23-25,46-47H2,1-2H3,(H2,48,55)(H,50,58)(H,51,59)(H,52,56)(H,53,57)(H,54,60)/t27-,28+,36+,37-,38-,39+/m1/s1
InChIKey
HRNLPPBUBKMZMT-RDRUQFPZSA-N
SMILES
C(N)(=O)[C@H](CCCCN)NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C)NC(=O)[C@@H](CC1=CC=C2C(=C1)C=CC=C2)NC(=O)[C@@H](C)N
CAS DataBase Reference
158861-67-7(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2056
Product name
Pralmorelin trifluoroacetate salt
Purity
≥97% (HPLC)
Packaging
1MG
Price
$162
Updated
2023/01/07
Sigma-Aldrich
Product number
SML2056
Product name
Pralmorelin trifluoroacetate salt
Purity
≥97% (HPLC)
Packaging
5MG
Price
$650
Updated
2023/01/07
Alfa Aesar
Product number
J66029
Product name
Growth Hormone Releasing Peptide-2
Packaging
25mg
Price
$270
Updated
2021/12/16
Alfa Aesar
Product number
J66029
Product name
Growth Hormone Releasing Peptide-2
Packaging
5mg
Price
$113
Updated
2021/12/16
Usbiological
Product number
382744
Product name
EIF3A
Packaging
96Tests
Price
$729
Updated
2021/12/16
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Pralmorelin Chemical Properties,Usage,Production

Description

Pralmorelin (also known as KP-102, GPA-748, GHRP-2, and Growth Hormone Releasing Peptide-2)  is a potent GH secretagogue in development as a diagnostic agent for growth hormone deficiency and for the treatment of pituitary disorders and GH deficiency. It acts as signal molecules that are involved in the control of cell growth and differentiation.

Uses

Growth hormone releasing factor. Pralmorelin is a growth hormone secretagogue that acts on the pituitary gland and the hypothalamus to stimulate and amplify pulsatile growth hormone release.

Definition

ChEBI: Pralmorelin is an oligopeptide.

benefits

Regulation of blood pressure, increased strength and healing, reduced injury, increased cell rejuvenation, increase in lean muscle mass and stronger bones.

Biochem/physiol Actions

Pralmorelin, also known as Growth hormone-releasing peptide 2 or GHRP-2, is an orally-active, synthetic peptide analogue of met-enkephalin that acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist to selectively stimulate the ghrelin receptor and cause growth hormone release. Pralmorelin (GHRP-2) has been used clinically for the assessment of growth hormone deficiency (GHD), It has also been shown to have anti-inflammatory activity.

Mechanism of action

GHRP-2 is an agonist of ghrelin, a gut peptide and also known as “the hunger hormone”, which binds to the growth hormone secretagogue receptor. Pralmorelin works to enhance natural growth hormone production in two ways. First, the GHRP-2 intensifies the natural growth hormone releasing signal, resulting in a substantial secretion of growth hormone. Second, it suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone (GHIH). Somatostatin generates the body to decrease its natural growth hormone production. By restricting the activity of somatostatin, GHRP-2 can improve growth hormone creation, resulting in increased natural growth hormone levels. GHRP-2 also activates ghrelin, a peptide hormone produced in the gastrointestinal system, which has strong effects on growth hormone production and appetite.

Pralmorelin Preparation Products And Raw materials

Raw materials

Preparation Products

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Pralmorelin Suppliers

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View Lastest Price from Pralmorelin manufacturers

Hebei Kangcang new material Technology Co., LTD
Product
GHRP-2 Acetate 158861-67-7
Price
US $80.00-50.00/box
Min. Order
2box
Purity
99%
Supply Ability
100000kg
Release date
2024-03-21
Hebei Yime New Material Technology Co., Ltd.
Product
GHRP-2 Acetate 158861-67-7
Price
US $15.00/mg
Min. Order
100mg
Purity
99%
Supply Ability
500boxes/day
Release date
2024-02-01
CONTIDE BIOTECH CO.,LTD
Product
GHRP-2 Acetate 158861-67-7
Price
US $0.00/G
Min. Order
1G
Purity
99%
Supply Ability
20kg
Release date
2024-03-22

158861-67-7, PralmorelinRelated Search:

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  • d-ala-β-(2-naphthyl)-d-ala-trp-d-phe-lys amide
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  • D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2
  • (DES-ALA3,D-ALA1,D-2-NAL2)-GHRP-6
  • (DES-ALA3)-GHRP-2
  • (DES-ALA3)-GROWTH HORMONE-RELEASING PEPTIDE-2
  • (DES-ALA3)-KP-102
  • (DES-ALA3)-PRALMORELIN
  • (DES-ALA8,D-ALA6,D-2-NAL7,D-PHE10)-ALPHA-MSH (6-11) AMIDE
  • H-D-ALA-D-2-NAL-ALA-TRP-D-PHE-LYS-NH2
  • H-D-ALA-D-2-NAL-TRP-D-PHE-LYS-NH2
  • H-D-ALA-D-ALA(2-NAPHTHYL)-TRP-D-PHE-LYS-NH2
  • GHRP-2
  • GHRP-2 ACETATE
  • GROWTH HORMONE RELEASING PROTEIN-2
  • (D-ALA1,D-2-NAL2)-GHRP-6 TRIFLUOROACETATE SALT
  • D-ala-B-(2-naphthyl)-D-ala-trp-D-phe-*lys amide
  • -2
  • (Tetrahydro-2H-pyran-4-yl)methoxy=pyrimidine-4-carboxylic acid
  • npvp npvp npvp apvp replacement China supplier npvp manufacturer npvp Crystal Skype:sale8_120
  • Pralmorelin GHRP-2
  • Monoclonal Anti-MAP Kinase, Activated/monophosphorylated (Phosphothreonine ERK-1&amp
  • Growth Hormone Releasing Factor (GHRF)-2
  • GHRP-2 (Growth Hormone Releasing Peptide)
  • GHCA
  • D-ALANYL-3-(2-NAPHTHALENYL)-D-ALANYL-L-ALANYL-L-TRYPTOPHYL-D-PHENYLALANYL-L-LYSINAMIDE ACETATE ADDUCT
  • GHRP-2 (FREE PEPTIDE)
  • (2S)-6-amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-naphthalen-2-yl-propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]-N-[(2R)-2-aminopropanoyl]hexanamide
  • D-Ala-bata-(2-naphthyl)-D-Ala-Trp-D-Phe-Lys amide
  • D-Alanyl-3-(2-naphthalenyl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide
  • D-Ala-D-β-Nal-Ala-Trp-D-Phe-Lys-NH2
  • 4-dichloro-1
  • 8-naphthyridine
  • 3-d]pyriMidine TFA
  • 2-trifluoroethyl)thiazole
  • 5-(Tributylstannyl)-2-(2
  • 3-a]pyrazine-3
  • 4]triazolo[4
  • 6-dihydro-[1
  • 7-tert-butyl 3-ethyl 5
  • 7-naphthyridine-3
  • 7-tert-butyl 3-Methyl 5
  • 4]triazine-6-carboxylate
  • ethyl 4-chloropyrrolo[1
  • tert-butyl 3-Methoxy-5
  • 2-trifluoroethyl)cyclopropyl)stannane
  • Tributyl(2-(2
  • CHRP-2
  • GHRP
  • Growth HorMone Releasing Hexapeptide-2
  • Monoclonal Anti-MAP Kinase, Activated (Diphosphorylated ERK-1&amp
  • EIF3A
  • GH secretagogue receptor
  • GH-releasing peptide receptor
  • GHS receptor