2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE

Product Name: 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
CAS No.: 117719-17-2
Chemical Name: 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
Synonyms: 5-BroMo-3-Morpholinopyrazin-2-aMine;5-bromo-3-morpholin-4-ylpyrazin-2-amine;5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE;2-Pyrazinamine, 5-bromo-3-(4-morpholinyl)-
CBNumber: CB11091233
Molecular Formula: C8H11BrN4O
Formula Weight: 259.1
MOL File: 117719-17-2.mol

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2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Property

storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T144347
Product name: 5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE
Purity: AldrichCPR
Packaging: 10MG
Price: $28.6
Updated: 2023/06/20

TRC

Product number: B699773
Product name: 5-Bromo-3-morpholinopyrazin-2-amine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

ChemScene

Product number: CS-0018855
Product name: 5-Bromo-3-morpholin-4-ylpyrazin-2-amine
Packaging: 250mg
Price: $67
Updated: 2021/12/16

Matrix Scientific

Product number: 072228
Product name: 2-Amino-5-bromo-3-morpholin-4-ylpyrazine
Purity: 95+%
Packaging: 1g
Price: $108
Updated: 2021/12/16

ChemScene

Product number: CS-0018855
Product name: 5-Bromo-3-morpholin-4-ylpyrazin-2-amine
Packaging: 1g
Price: $134
Updated: 2021/12/16

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2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Chemical Properties,Usage,Production

Synthesis

110-91-8

24241-18-7

117719-17-2

General procedure for the synthesis of 2-amino-5-bromo-3-morpholin-4-ylpyrazine from morpholine and 2-amino-3,5-dibromopyrazine: intermediate 1-01 (15 g, 59.3 mmol) was dissolved in morpholine (15 ml, 178 mmol), and the resulting solution was subjected to a Parr reactor and heated for 48 hours at 120 °C. Upon completion of the reaction, a brown solid was observed to be produced. The solid was suspended in dichloromethane (DCM) and washed twice sequentially with aqueous sodium bicarbonate (NaHCO3). The organic phase was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to dryness under reduced pressure to afford the target product I-02 as a brown solid in a yield of 14.8 g in 96% yield.

References

[1] Patent: WO2011/36461, 2011, A1. Location in patent: Page/Page column 77
[2] Tetrahedron Letters, 2012, vol. 53, # 9, p. 1082 - 1084
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1874 - 1878
[4] Patent: US2012/83492, 2012, A1. Location in patent: Page/Page column 91
[5] Molecules, 2017, vol. 22, # 2,

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Suppliers

China 26 Czech Republic 1 Germany 1 Hungary 1 India 1 United Kingdom 1 United States 7 Global 38

InFarmatik Bt.

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Email: ruf.szilvi@infarmatik.hu
Country: Hungary
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117719-17-2, 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINERelated Search:

(2-AMINO-5-BROMOPHENYL)METHANOL 2-Amino-5-bromo-4-chloro-3-nitropyridine 2-AMINO-5-BROMO-3-PIPERIDIN-1-YLPYRAZINE 2-Amino-5-bromobenzaldehyde 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE 2-BROMO-6-MORPHOLINOPYRAZINE 2-AMINO-5-BROMO-3-(DIMETHYLAMINO)PYRAZINE 5-BROMO-N3-METHYL-PYRAZINE-2,3-DIAMINE 2-AMINO-3-(ETHYLAMINO)PYRAZINE 2-AMINO-5-BROMO-3-(ETHYLAMINO)PYRAZINE 2-AMINO-5-BROMO-3-(DIETHYLAMINO)PYRAZINE 5-BROMO-PYRAZINE-2,3-DIAMINE 2-AMINO-3-MORPHOLIN-4-YLPYRAZINE 2-AMINO-3-(DIMETHYLAMINO)PYRAZINE 2-AMINO-3-(DIETHYLAMINO)PYRAZINE 6-BROMOPYRAZIN-2-AMINE 2-Bromopyrazine 2-Amino-5-bromopyrazine

5-bromo-3-morpholin-4-ylpyrazin-2-amine

5-BroMo-3-Morpholinopyrazin-2-aMine

2-Pyrazinamine, 5-bromo-3-(4-morpholinyl)-

5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE

117719-17-2

C8H11BrN4O