4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER
- Product Name
- 4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER
- CAS No.
- 872091-83-3
- Chemical Name
- 4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER
- Synonyms
- 3-Cyanomethyl-4-chlorobenzoic acid methyl ester;4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER;Methyl 4-chloro-3-(cyanomethyl)benzoate - [M71997];3-Cyanomethyl-4-Chorobenzoic Acid Methyl Ester (en);Benzoic acid, 4-chloro-3-(cyanomethyl)-, methyl ester
- CBNumber
- CB11092669
- Molecular Formula
- C10H8ClNO2
- Formula Weight
- 209.63
- MOL File
- 872091-83-3.mol
4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER Property
- Density
- 1.266
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- M342988
- Product name
- Methyl4-chloro-3-(cyanomethyl)benzoate
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CS-0045070
- Product name
- Methyl4-chloro-3-(cyanomethyl)benzoate
- Packaging
- 1g
- Price
- $37
- Updated
- 2021/12/16
- Product number
- CS-0045070
- Product name
- Methyl4-chloro-3-(cyanomethyl)benzoate
- Packaging
- 5g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- X2842
- Product name
- Methyl4-chloro-3-(cyanomethyl)benzoate
- Packaging
- 1g
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 4637-5-Z7
- Product name
- Methyl 4-chloro-3-(cyanomethyl)benzoate
- Purity
- 98%
- Packaging
- 5G
- Price
- $109
- Updated
- 2021/12/16
4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
220464-68-6
7677-24-9
872091-83-3
Step 2: Synthesis of intermediate 2 A mixture of Intermediate 1 (methyl 3-(bromomethyl)-4-chlorobenzoate, 1.00 g, 3.80 mmol), trimethylcyanosilane (TMSCN, 0.56 g, 5.69 mmol), and potassium carbonate (K2CO3, 786 mg, 5.69 mmol) in acetonitrile (CH3CN, 50 mL) was heated to reflux for 16 hours. After completion of the reaction, the mixture was cooled to room temperature, filtered to remove insoluble material and the filtrate was concentrated. The resulting crude product was purified by silica gel column chromatography using a hexane solution of 5-10% ethyl acetate (EtOAc) as eluent to afford the target product methyl 3-cyanomethyl-4-chlorobenzoate (590 mg, 75% yield) as a white solid. 1H NMR (400 MHz, CDCl3) δ: 8.18 (d, 1H), 7.99 (dd, 1H), 7.52 (d, 1H), 3.94 (s, 3H), 3.88 (s, 2H).
References
[1] Patent: WO2014/144737, 2014, A1. Location in patent: Paragraph 00777
4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
4-CHLORO-3-CYANOMETHYL-BENZOIC ACID METHYL ESTER Suppliers
- Tel
- --
- Fax
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- enquiries@fluorochem.co.uk
- Country
- United Kingdom
- ProdList
- 6401
- Advantage
- 74