ChemicalBook > CAS DataBase List > Nemorubicin

Nemorubicin

Product Name
Nemorubicin
CAS No.
108852-90-0
Chemical Name
Nemorubicin
Synonyms
MMRDX;DMM Dox;FCE 23762;PNU 152243;Nemorubicin;PNU-152243A;Nemorubicina;NeMorubincine;-Dichlorobenzophenone;Nemorubicin (PNU 152243)
CBNumber
CB11179292
Molecular Formula
C32H37NO13
Formula Weight
643.64
MOL File
108852-90-0.mol
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Nemorubicin Property

Boiling point:
852.2±65.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:60.0(Max Conc. mg/mL);101.0(Max Conc. mM)
pka
7.35±0.60(Predicted)
form 
Powder
color 
Orange to reddish brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
N389838
Product name
Nemorubicin
Packaging
1mg
Price
$615
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0024400
Product name
NEMORUBICIN
Purity
95.00%
Packaging
1MG
Price
$930.3
Updated
2021/12/16
Crysdot
Product number
CD31004619
Product name
Nemorubicin
Purity
98+%
Packaging
10mg
Price
$977
Updated
2021/12/16
Crysdot
Product number
CD31004619
Product name
Nemorubicin
Purity
98+%
Packaging
5mg
Price
$638
Updated
2021/12/16
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Nemorubicin Chemical Properties,Usage,Production

Uses

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway, where current therapies fail. Nemorubicin is biotransformed in the liver into cytotoxic metabolites that may further contribute to render this drug highly active against primary liver tumors or liver metastases.

Definition

ChEBI: Nemorubicin is a member of morpholines, an anthracycline antibiotic, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a doxorubicin.

target

cancer

Nemorubicin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nemorubicin Suppliers

China 70 United States 11 Global 81
Zhenjiang Renzhi Biotechnology Co., Ltd.
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View Lastest Price from Nemorubicin manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Nemorubicin 108852-90-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Nemorubicin 108852-90-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
Nemorubicin 108852-90-0
Price
US $6.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 5kg, 50kg
Release date
2020-01-09

108852-90-0, NemorubicinRelated Search:

1,8-Dihydroxyanthraquinone Adriamycin Doxorubicinone Nemorubicin Idarubicin Chrysophanic acid 2-Ethyl anthraquinone DIETHANOL PROPANOLAMINE N,N-BIS(2-HYDROXYETHYL)ISOPROPANOLAMINE 1,5-DIHYDROXYANTHRAQUINONE 2,4-DIMETHYL-2'-METHOXYBENZOPHENONE 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2,5-DIMETHYL-3'-METHOXYBENZOPHENONE N-ETHYL-TETRAHYDRO-2H-PYRAN-4-AMINE 14-Hydroxy Carminomycin 2-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN Feudomycin A

  • Nemorubicin
  • 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-2,3,6-trideoxy-3-(2S)-2-methoxy-4-morpholinyl-.alpha.-L-lyxo-hexopyranosyloxy-, (8S,10S)-
  • methoxy-morpholynil-doxorubicin
  • NeMorubincine
  • PNU152243A; PNU-152243A; PNU 152243A; NEMORUBICIN; METHOXYMORPHOLINYL-DOXORUBICIN
  • (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 2,3,6-trideoxy-3-[(S)-2-methoxymorpholino]-alpha-L-lyxo-hexopyranoside
  • DMM Dox
  • FCE 23762
  • Methoxymorpholinyldoxorubicin
  • MMRDX
  • (1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranoside
  • PNU 152243
  • PNU-152243A
  • Nemorubicin (PNU 152243)
  • 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
  • 5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-a-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-
  • FCE 23762,FCE-23762,PNU-152243,PNU152243,inhibit,Methoxymorpholinyl doxorubicin,Inhibitor,Nemorubicin,FCE23762
  • Nemorubicina
  • -Dichlorobenzophenone
  • (8S,10S)-6,8,11-Trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-((S)-2-methoxymorpholino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
  • 108852-90-0
  • 108852-90-1
  • ≧99%