Nemorubicin

Product Name: Nemorubicin
CAS No.: 108852-90-0
Chemical Name: Nemorubicin
Synonyms: MMRDX;DMM Dox;FCE 23762;PNU 152243;Nemorubicin;PNU-152243A;Nemorubicina;NeMorubincine;-Dichlorobenzophenone;Nemorubicin (PNU 152243)
CBNumber: CB11179292
Molecular Formula: C32H37NO13
Formula Weight: 643.64
MOL File: 108852-90-0.mol

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Nemorubicin Property

Boiling point:: 852.2±65.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:60.0(Max Conc. mg/mL);101.0(Max Conc. mM)
pka: 7.35±0.60(Predicted)
form: Powder
color: Orange to reddish brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: N389838
Product name: Nemorubicin
Packaging: 1mg
Price: $615
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0024400
Product name: NEMORUBICIN
Purity: 95.00%
Packaging: 1MG
Price: $930.3
Updated: 2021/12/16

Crysdot

Product number: CD31004619
Product name: Nemorubicin
Purity: 98+%
Packaging: 10mg
Price: $977
Updated: 2021/12/16

Crysdot

Product number: CD31004619
Product name: Nemorubicin
Purity: 98+%
Packaging: 5mg
Price: $638
Updated: 2021/12/16

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Nemorubicin Chemical Properties,Usage,Production

Uses

Nemorubicin is a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway, where current therapies fail. Nemorubicin is biotransformed in the liver into cytotoxic metabolites that may further contribute to render this drug highly active against primary liver tumors or liver metastases.

Definition

ChEBI: Nemorubicin is a member of morpholines, an anthracycline antibiotic, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a doxorubicin.

target

cancer

Nemorubicin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nemorubicin Suppliers

China 70 United States 11 Global 81

Zhenjiang Renzhi Biotechnology Co., Ltd.

Tel: 18762678737
Email: 751546636@qq.com
Country: China
ProdList: 38
Advantage: 58

WuYan Pharmaceutical Technology (Shanghai) Co., Ltd.

Tel: 021-61001086 13671938079
Fax: 021-61114075
Email: sales@wuyanpharm.com
Country: China
ProdList: 104
Advantage: 55

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1874
Advantage: 55

Levena Biopharma Co., Ltd.

Tel: 025-58073912 1482480248
Fax: 025-58073911
Email: service@levena.cn
Country: China
ProdList: 6
Advantage: 58

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

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View Lastest Price from Nemorubicin manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nemorubicin 108852-90-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: Nemorubicin 108852-90-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: Nemorubicin 108852-90-0
Price: US $6.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg, 5kg, 50kg
Release date: 2020-01-09

108852-90-0, NemorubicinRelated Search:

1,8-Dihydroxyanthraquinone Adriamycin Doxorubicinone Nemorubicin Idarubicin Chrysophanic acid 2-Ethyl anthraquinone DIETHANOL PROPANOLAMINE N,N-BIS(2-HYDROXYETHYL)ISOPROPANOLAMINE 1,5-DIHYDROXYANTHRAQUINONE 2,4-DIMETHYL-2'-METHOXYBENZOPHENONE 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2,5-DIMETHYL-3'-METHOXYBENZOPHENONE N-ETHYL-TETRAHYDRO-2H-PYRAN-4-AMINE 14-Hydroxy Carminomycin 2-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN Feudomycin A

Nemorubicin

5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-2,3,6-trideoxy-3-(2S)-2-methoxy-4-morpholinyl-.alpha.-L-lyxo-hexopyranosyloxy-, (8S,10S)-

methoxy-morpholynil-doxorubicin

NeMorubincine

PNU152243A; PNU-152243A; PNU 152243A; NEMORUBICIN; METHOXYMORPHOLINYL-DOXORUBICIN

(1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 2,3,6-trideoxy-3-[(S)-2-methoxymorpholino]-alpha-L-lyxo-hexopyranoside

DMM Dox

FCE 23762

Methoxymorpholinyldoxorubicin

MMRDX

(1S,3S)-3-Glycoloyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranoside

PNU 152243

PNU-152243A

Nemorubicin (PNU 152243)

5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-

5,12-Naphthacenedione,7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2S)-2-methoxy-4-morpholinyl]-a-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-

FCE 23762,FCE-23762,PNU-152243,PNU152243,inhibit,Methoxymorpholinyl doxorubicin,Inhibitor,Nemorubicin,FCE23762

Nemorubicina

-Dichlorobenzophenone

(8S,10S)-6,8,11-Trihydroxy-10-(((2R,4S,5S,6S)-5-hydroxy-4-((S)-2-methoxymorpholino)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

108852-90-0

108852-90-1

≧99%