2-CHLOROETHYL P-TOLUENESULFONATE
- Product Name
- 2-CHLOROETHYL P-TOLUENESULFONATE
- CAS No.
- 80-41-1
- Chemical Name
- 2-CHLOROETHYL P-TOLUENESULFONATE
- Synonyms
- 2-chloroethyltosylate;2-Chloroethyl tosylate;2-tosyloxyethylchloride;2-Chloroethyl p-tosylate;2-Chloroethanol tosylate;-Chloroethyl-p-toluenesulfnate;2-CHLOROETHYL P-TOLUENESULFONATE;2-CHLOROETHYL 4-TOLUENESULFONATE;β-Chloroethyl p-toluenesulfonate;2-CHLOROETHYL P-TOLUENESULPHONATE
- CBNumber
- CB1133536
- Molecular Formula
- C9H11ClO3S
- Formula Weight
- 234.7
- MOL File
- 80-41-1.mol
2-CHLOROETHYL P-TOLUENESULFONATE Property
- Melting point:
- 157-161℃
- Boiling point:
- 153 °C0.3 mm Hg(lit.)
- Density
- 1.294 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.529(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Liquid
- color
- Clear colorless to yellow
- BRN
- 1968816
- CAS DataBase Reference
- 80-41-1(CAS DataBase Reference)
- EPA Substance Registry System
- Ethanol, 2-chloro-, 4-methylbenzenesulfonate (80-41-1)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22
- Safety Statements
- 23-36/37/39-24/25
- RIDADR
- 2810
- WGK Germany
- 3
- RTECS
- XT6475000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29055900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H320Causes eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 107999
- Product name
- 2-Chloroethyl p-toluenesulfonate
- Purity
- 97%
- Packaging
- 25g
- Price
- $62.51
- Updated
- 2025/07/31
- Product number
- 107999
- Product name
- 2-Chloroethyl p-toluenesulfonate
- Purity
- 97%
- Packaging
- 100g
- Price
- $240
- Updated
- 2025/07/31
- Product number
- C2380
- Product name
- 2-Chloroethyl p-Toluenesulfonate
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- C2380
- Product name
- 2-Chloroethyl p-Toluenesulfonate
- Purity
- >98.0%(GC)
- Packaging
- 100g
- Price
- $147
- Updated
- 2025/07/31
- Product number
- C363215
- Product name
- 2-Chloroethyl4-methylbenzenesulfonate
- Packaging
- 50g
- Price
- $90
- Updated
- 2021/12/16
2-CHLOROETHYL P-TOLUENESULFONATE Chemical Properties,Usage,Production
Chemical Properties
CLEAR COLOURLESS TO YELLOW LIQUID
Uses
2-Chloroethyl 4-methylbenzenesulfonate is a useful reactant for the synthesis of triphenylethanamine derivatives, and fluorinated carbazole derivatives.
Uses
2-Chloroethyl p-toluenesulfonate was used to develop method for the determination of a variety of hydrophobic aromatic sulfonates by micellar electrokinetic chromatography.
Synthesis Reference(s)
The Journal of Organic Chemistry, 53, p. 5783, 1988 DOI: 10.1021/jo00259a035
Synthesis
98-59-9
107-07-3
80-41-1
General procedure for the synthesis of p-toluenesulfonic acid-β-chloroethyl ester from p-toluenesulfonyl chloride and 2-chloroethanol: 1. 180mL of dichloromethane (DCM) was added to a 1L round bottom flask (RBF) to which p-toluenesulfonyl chloride (172g, 0.884mol) and pyridine (59g, 0.75mol) were added, and the flask was cooled in an ice bath for about 5 minutes. 2. 2-chloroethanol (40.3 g, 0.496 mol) was added slowly, then the flask was removed from the ice bath and stirred at room temperature (r.t.) for 15 hours. 3. The reaction mixture was poured into a 1 L dispensing funnel and washed sequentially twice with a mixture of 300 mL of water plus 50 mL of pyridine, and then washed with 300 mL of water plus 75 mL of aqueous hydrochloric acid 36% wt (the aqueous phase was discarded after each wash). 4. The solvent was removed under reduced pressure to afford analytically pure p-toluenesulfonic acid-β-chloroethyl ester (1) as a pale yellow, thick, syrupy product (116 g, 0.494 mol, 100% yield). 1H NMR data: δ= 7.81 (d, 2H, aromatic, interstitial with CH3, J = 8.3 Hz), 7.37 (d, 2H, aromatic, adjacent to CH3, J = 8.3 Hz), 4.23 (t, OCH2, J = 5.9 Hz), 3.66 (t, CH2Cl, J = 5.9 Hz), 2.46 (s, CH3).
References
[1] Patent: WO2009/52148, 2009, A1. Location in patent: Page/Page column 29
[2] Recueil des Travaux Chimiques des Pays-Bas, 1990, vol. 109, # 3, p. 147 - 153
[3] Patent: WO2010/3048, 2010, A1. Location in patent: Page/Page column 87-88
[4] Synthesis, 1993, # 11, p. 1141 - 1144
[5] Journal of Organic Chemistry, 2000, vol. 65, # 17, p. 5136 - 5142
2-CHLOROETHYL P-TOLUENESULFONATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLOROETHYL P-TOLUENESULFONATE manufacturers
- Product
- 2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.2%
- Supply Ability
- 100 tons
- Release date
- 2022-02-18
- Product
- 2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-10