ChemicalBook > CAS DataBase List > 2-CHLOROETHYL P-TOLUENESULFONATE

2-CHLOROETHYL P-TOLUENESULFONATE

Product Name
2-CHLOROETHYL P-TOLUENESULFONATE
CAS No.
80-41-1
Chemical Name
2-CHLOROETHYL P-TOLUENESULFONATE
Synonyms
2-chloroethyltosylate;2-Chloroethyl tosylate;2-tosyloxyethylchloride;2-Chloroethyl p-tosylate;2-Chloroethanol tosylate;-Chloroethyl-p-toluenesulfnate;2-CHLOROETHYL P-TOLUENESULFONATE;2-CHLOROETHYL 4-TOLUENESULFONATE;β-Chloroethyl p-toluenesulfonate;2-CHLOROETHYL P-TOLUENESULPHONATE
CBNumber
CB1133536
Molecular Formula
C9H11ClO3S
Formula Weight
234.7
MOL File
80-41-1.mol
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2-CHLOROETHYL P-TOLUENESULFONATE Property

Melting point:
157-161℃
Boiling point:
153 °C0.3 mm Hg(lit.)
Density 
1.294 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.529(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid
color 
Clear colorless to yellow
BRN 
1968816
CAS DataBase Reference
80-41-1(CAS DataBase Reference)
EPA Substance Registry System
Ethanol, 2-chloro-, 4-methylbenzenesulfonate (80-41-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
23-36/37/39-24/25
RIDADR 
2810
WGK Germany 
3
RTECS 
XT6475000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29055900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
107999
Product name
2-Chloroethyl p-toluenesulfonate
Purity
97%
Packaging
25g
Price
$62.51
Updated
2025/07/31
Sigma-Aldrich
Product number
107999
Product name
2-Chloroethyl p-toluenesulfonate
Purity
97%
Packaging
100g
Price
$240
Updated
2025/07/31
TCI Chemical
Product number
C2380
Product name
2-Chloroethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
25g
Price
$49
Updated
2025/07/31
TCI Chemical
Product number
C2380
Product name
2-Chloroethyl p-Toluenesulfonate
Purity
>98.0%(GC)
Packaging
100g
Price
$147
Updated
2025/07/31
TRC
Product number
C363215
Product name
2-Chloroethyl4-methylbenzenesulfonate
Packaging
50g
Price
$90
Updated
2021/12/16
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2-CHLOROETHYL P-TOLUENESULFONATE Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO YELLOW LIQUID

Uses

2-Chloroethyl 4-methylbenzenesulfonate is a useful reactant for the synthesis of triphenylethanamine derivatives, and fluorinated carbazole derivatives.

Uses

2-Chloroethyl p-toluenesulfonate was used to develop method for the determination of a variety of hydrophobic aromatic sulfonates by micellar electrokinetic chromatography.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 5783, 1988 DOI: 10.1021/jo00259a035

Synthesis

98-59-9

107-07-3

80-41-1

General procedure for the synthesis of p-toluenesulfonic acid-β-chloroethyl ester from p-toluenesulfonyl chloride and 2-chloroethanol: 1. 180mL of dichloromethane (DCM) was added to a 1L round bottom flask (RBF) to which p-toluenesulfonyl chloride (172g, 0.884mol) and pyridine (59g, 0.75mol) were added, and the flask was cooled in an ice bath for about 5 minutes. 2. 2-chloroethanol (40.3 g, 0.496 mol) was added slowly, then the flask was removed from the ice bath and stirred at room temperature (r.t.) for 15 hours. 3. The reaction mixture was poured into a 1 L dispensing funnel and washed sequentially twice with a mixture of 300 mL of water plus 50 mL of pyridine, and then washed with 300 mL of water plus 75 mL of aqueous hydrochloric acid 36% wt (the aqueous phase was discarded after each wash). 4. The solvent was removed under reduced pressure to afford analytically pure p-toluenesulfonic acid-β-chloroethyl ester (1) as a pale yellow, thick, syrupy product (116 g, 0.494 mol, 100% yield). 1H NMR data: δ= 7.81 (d, 2H, aromatic, interstitial with CH3, J = 8.3 Hz), 7.37 (d, 2H, aromatic, adjacent to CH3, J = 8.3 Hz), 4.23 (t, OCH2, J = 5.9 Hz), 3.66 (t, CH2Cl, J = 5.9 Hz), 2.46 (s, CH3).

References

[1] Patent: WO2009/52148, 2009, A1. Location in patent: Page/Page column 29
[2] Recueil des Travaux Chimiques des Pays-Bas, 1990, vol. 109, # 3, p. 147 - 153
[3] Patent: WO2010/3048, 2010, A1. Location in patent: Page/Page column 87-88
[4] Synthesis, 1993, # 11, p. 1141 - 1144
[5] Journal of Organic Chemistry, 2000, vol. 65, # 17, p. 5136 - 5142

2-CHLOROETHYL P-TOLUENESULFONATE Preparation Products And Raw materials

Raw materials

2-Chloroethanol Tosyl chloride

Preparation Products

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2-CHLOROETHYL P-TOLUENESULFONATE Suppliers

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View Lastest Price from 2-CHLOROETHYL P-TOLUENESULFONATE manufacturers

Honest Joy Holdings Limited
Product
2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98.2%
Supply Ability
100 tons
Release date
2022-02-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
2-CHLOROETHYL P-TOLUENESULFONATE 80-41-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-10

80-41-1, 2-CHLOROETHYL P-TOLUENESULFONATERelated Search:

Methyl benzenesulfonate 2-Chloroethanol Sodium methanesulfinate p-Toluenethiol Methyl toluenesulfonate 2-CHLOROETHYL P-TOLUENESULFONATE p-Toluenesulfonic acid BENZENESULFINIC ACID Ethyl methanesulfonate AMMONIUM METHANESULFONATE Methyl methanesulfonate Sulfur dioxide Ethyl p-toluenesulfonate Ethyl benzenesulphonate P-TOLUENESULFINIC ACID Thiophenol METHYL BENZENESULFINATE Benzenesulfonic acid

  • P-TOLUENESULFONIC ACID 2-CHLOROETHYL ESTER
  • BETA-CHLOROETHYL-P-TOLUENE SULFONATE
  • 2-CHLOROETHYL P-TOLUENESULFONATE
  • 2-CHLOROETHYL P-TOLUENESULPHONATE
  • 2-(p-Toluenesulfonyloxy)ethyl chloride
  • 3-(2-chloroethyl)-4-methylbenzenesulfonate
  • 2-Chlorethylester kyseliny p-toluensulfonove
  • 2-chlorethylesterkyselinyp-toluensulfonove
  • 2-chloro-ethano4-methylbenzenesulfonate
  • 2-Chloroethanol p-toluenesulfonate
  • 2-chloroethanol4-methylbenzenesulfonate
  • 2-chloroethanolp-toluenesulfonate
  • 2-chloro-ethanop-toluenesulfonate
  • 2-Chloroethyl 4-methylbenzenesulfonate
  • 2-Chloroethyl para-toluenesulfonate
  • 2-Chloroethyl p-tosylate
  • 2-Chloroethyl tosylate
  • 2-chloroethyltosylate
  • 2-tosyloxyethylchloride
  • 4-Toluenesulfonicacid2-chloroethylester
  • beta-Chloroethylester kyseliny p-toluensulfonove
  • beta-chloroethylesterkyselinyp-toluensulfonove
  • -Chloroethyl-p-toluenesulfnate
  • Ethanol, 2-chloro-, p-toluenesulfonate
  • p-Toluenesulfonic acid, beta-chloroethyl ester
  • p-toluenesulfonicacid,beta-chloroethylester
  • 4-Methylbenzenesulfonic acid 2-chloroethyl ester
  • 2-Chloroethyl-p-toluenesulfonate,97%
  • p-Toluenesulphonic acid 2-chloroethyl ester
  • 2-chloroethyl toluene-4-sulphonate
  • 2-CHLOROETHYL 4-TOLUENESULFONATE
  • 2-Chloro-1-(p-toluenesulfonyl)ethane
  • 2-Chloroethanol tosylate
  • 2-Chloroethyl p-toluenesulfonate 97%
  • 2-Chloroethyl <i>p</i>-Toluenesulfonate
  • 2-Chloroethyl p-Toluenesulfonate &gt
  • Ethanol, 2-chloro-, 1-(4-methylbenzenesulfonate)
  • β-Chloroethyl p-toluenesulfonate
  • 2-chloroethyl 4-methylbenzene-1-sulfonate
  • 80-41-1
  • CH3C6H4SO3CH2CH2Cl
  • C9H11ClO3S
  • Building Blocks
  • Organic Building Blocks
  • Tosylates
  • Sulfur Compounds
  • Organic Building Blocks
  • Sulfur Compounds
  • Tosylates