ChemicalBook > CAS DataBase List > 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID

1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID

Product Name
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
CAS No.
10315-07-8
Chemical Name
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
Synonyms
BUTTPARK 33\04-90;Bzl-isonipecotic acid;1-BENZYL-ISONIPECOTIC ACID;N-BENZYL-ISONIPECOTIC ACID;1-benzylpiperidin-4-carboxylic acid;1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID;N-Benzylpiperidine-4-carboxylic acid;N-Benzyl-4-Piperidinecarboxylic acid;1-BENZYL-4-PIPERIDINE CARBOXYLIC ACID;1-N-Benzyl-pipeidine-4-carboxylic acid
CBNumber
CB1150793
Molecular Formula
C13H17NO2
Formula Weight
219.28
MOL File
10315-07-8.mol
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1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Property

Melting point:
169.0-170.5 °C
Boiling point:
358.6±35.0 °C(Predicted)
Density 
1.165
storage temp. 
2-8°C
form 
powder to crystal
pka
4.02±0.20(Predicted)
color 
White to Almost white
CAS DataBase Reference
10315-07-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
Hazard Note 
Irritant
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5826
Product name
1-Benzylpiperidine-4-carboxylic Acid
Packaging
1G
Price
$131
Updated
2025/07/31
TCI Chemical
Product number
B5826
Product name
1-Benzylpiperidine-4-carboxylic Acid
Packaging
5G
Price
$436
Updated
2025/07/31
TRC
Product number
B288993
Product name
1-Benzylpiperidine-4-carboxylic Acid
Packaging
50mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
17174
Product name
Bzl-isonipecoticacid,97%(HPLC)
Purity
97%(HPLC)
Packaging
1G
Price
$28
Updated
2021/12/16
Apolloscientific
Product number
OR5690
Product name
1-Benzylpiperidine-4-carboxylic acid
Packaging
1g
Price
$41
Updated
2021/12/16
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1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

24228-40-8

10315-07-8

(b) Synthesis of 1-benzyl-4-piperidinecarboxylic acid: 4N aqueous sodium hydroxide solution (35 mL) was added to a solution of ethyl 1-benzyl-4-piperidinecarboxylate (16.1 g, 65.1 mmol) in tetrahydrofuran (70 mL). The reaction mixture was stirred at room temperature and 1,4-dioxane (70 mL) was added and stirring was continued overnight. Upon completion of the reaction, the pH of the reaction solution was adjusted to 7 with 2 N hydrochloric acid. subsequently, the solvent was removed by distillation under reduced pressure. The obtained residue was suspended in ethanol and the solid was collected by filtration. Finally, the filtrate was concentrated under reduced pressure to afford 1-benzyl-4-piperidine carboxylic acid (13.6 g, 95% yield).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 17, p. 4980 - 4983
[2] Patent: EP1500643, 2005, A1. Location in patent: Page 18
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 20, p. 6491 - 6503
[4] Helvetica Chimica Acta, 1997, vol. 80, # 5, p. 1528 - 1551
[5] Patent: US6020368, 2000, A

1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID Suppliers

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View Lastest Price from 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID 10315-07-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Career Henan Chemical Co
Product
1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID 10315-07-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-08

10315-07-8, 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACIDRelated Search:


  • BUTTPARK 33\04-90
  • 1-BENZYL-ISONIPECOTIC ACID
  • 1-BENZYLPIPERIDINE-4-CARBOXYLIC ACID
  • 1-BENZYL-4-PIPERIDINE CARBOXYLIC ACID
  • N-BENZYL-ISONIPECOTIC ACID
  • 1-(phenylmethyl)-4-Piperidinecarboxylic acid
  • N-Benzylpiperidine-4-carboxylic acid
  • 1-benzylpiperidin-4-carboxylic acid
  • 4-Piperidinecarboxylic acid, 1-(phenylMethyl)-
  • 1-Benzylisonipecotic acid, 1-Benzyl-4-carboxypiperidine
  • Bzl-isonipecotic acid
  • 1-N-Benzyl-pipeidine-4-carboxylic acid
  • N-Benzyl-4-Piperidinecarboxylic acid
  • 10315-07-8
  • pharmacetical
  • Carboxylic Acids
  • Pyrans, Piperidines &Piperazines
  • Carboxylic Acids
  • Pyrans, Piperidines & Piperazines