ChemicalBook > CAS DataBase List > 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one

Product Name: 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one
CAS No.: 184177-83-1
Chemical Name: 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one
Synonyms: ChemicalBook;2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one;1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one;1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one;2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one;PSZ-2;BSKZ-2;Posaconazole B;4-Triazol-3-one;Posaconazole POB
CBNumber: CB11553210
Molecular Formula: C30H35N5O3
Formula Weight: 513.63
MOL File: 184177-83-1.mol

Less

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one Property

Melting point:: 195-197oC
Boiling point:: 685.4±65.0 °C(Predicted)
Density: 1.22
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 12.18±0.30(Predicted)
form: Solid
color: White
InChIKey: QLRPRKJUMRQTOV-IADCTJSHSA-N
SMILES: N1=CN(C2=CC=C(N3CCN(C4=CC=C(O)C=C4)CC3)C=C2)C(=O)N1[C@@H](CC)[C@@H](OCC1=CC=CC=C1)C
CAS DataBase Reference: 184177-83-1(CAS DataBase Reference)

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

TRC

Product number: E925535
Product name: 2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one
Packaging: 1g
Price: $1040
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0068924
Product name: 2-[(1S,2S)-1-ETHYL-2-BENZYLOXYPROPYL]-2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
Purity: 95.00%
Packaging: 10MG
Price: $1963.5
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0068924
Product name: 2-[(1S,2S)-1-ETHYL-2-BENZYLOXYPROPYL]-2,4-DIHYDRO-4-[4-[4-(4-HYDROXYPHENYL)-1-PIPERAZINYL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
Purity: 95.00%
Packaging: 1MG
Price: $750.75
Updated: 2021/12/16

Matrix Scientific

Product number: 089902
Product name: 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
Purity: 95+%
Packaging: 5g
Price: $788
Updated: 2021/12/16

Ark Pharm

Product number: AK-89728
Product name: 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
Purity: 98+%
Packaging: 1g
Price: $43
Updated: 2021/12/16

Less

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one Chemical Properties,Usage,Production

Chemical Properties

Grey Solid

Uses

Intermediate in the preparation of Posaconazole (P689600).

Synthesis

184177-81-9

170985-85-0

184177-83-1

Synthesis of 4-(4-(4-(4-(4-hydroxyphenyl)-1 -piperidinyl)phenyl)-2-[(1S,2S)-1 -ethyl-2-(benzyloxy)propyl]-2,4-dihydro-3H-1 ,2,. 4-triazol-3-one was carried out in the following general steps: the N'-((2S,3S)-2-(benzyloxy)pentan-3-yl)formylhydrazine compound of formula-17 obtained in Example 13 (45.5 g) was mixed with dioxane (500 ml), and 4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenylcarbamate compound (50 g) was added and heated to 90-100 °C. Triethylamine (26 g) was added to the reaction mixture at 90-100 °C and kept at this temperature with stirring for 24 hours. After completion of the reaction, the reaction mixture was cooled to 25-30 °C and dichloromethane was added. The reaction mixture was filtered through a hyflow bed and washed with dichloromethane. Water was added to the filtrate to separate the organic and aqueous layers, and the aqueous layer was extracted with dichloromethane. The organic layers were combined and washed sequentially with 2% sodium hydroxide solution, water, 5% hydrochloric acid solution, water, and 5% NaHCO3 solution. The solvent in the organic layer was distilled under reduced pressure to obtain the target product. Isopropanol (75 ml) was added to the resulting compound, cooled to 25-30°C and stirred for 6 hours. The solid was filtered, washed with isopropanol and dried to give 4-(4-(4-(4-hydroxyphenyl)-1-piperidinyl)phenyl)-2-[(1S,2S)-1-ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-3H-1,2,4-triazol-3-one. Yield: 28 g; HPLC purity: 97.67%; impurity-A: 0.37%. b) Purification of compound of formula-20: The obtained compound of formula-20 (30 g) was dissolved in methanol (960 ml) and heated to 60-65°C to dissolve. The reaction mixture was cooled to 25-30°C and stirred at the same temperature for 30 min. The precipitated solid was filtered and dried to give pure compound of formula-20. Yield: 70%; HPLC purity: 99.15%; impurity-A: 0.09%.

References

[1] Patent: US2014/343285, 2014, A1. Location in patent: Paragraph 0340; 0341; 0342

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one Suppliers

Canada 1 China 316 India 9 United Kingdom 1 United States 9 Global 336

Xi'an Manareco New Materials Co., Ltd.

Tel: 029-68669089-8816
Fax: +86-29-68669073
Email: market@xarlm.com
Country: China
ProdList: 499
Advantage: 55

Tianjin Chempharmatech Co.,Ltd.

Tel: 022-66211079 13212288319
Fax: qq1405432731
Email: sales@chempharmatech.com
Country: China
ProdList: 918
Advantage: 55

INTERCHEMIE NANJING PHARMATECH CO., LTD

Tel: 13656237714 13656237714;
Fax: 0512-65852853
Email: xiaokunfu@kyyykj.com
Country: China
ProdList: 295
Advantage: 55

Chengdu Better Pharmaceutical Technology Co.,Ltd.

Tel: 18280102635; 18280102635
Fax: 028-82252524
Email: sales@betterwanhe.com
Country: China
ProdList: 61
Advantage: 55

Gansu HaoTian Chemical Technology Co., Ltd.

Tel: 0943-6900332 17789447501
Fax: 0931-8238232
Email: zhuanxiajiang@haotianpharm.com
Country: China
ProdList: 192
Advantage: 55

Shaanxi Lvyuan Biomedical Co., Ltd

Tel: 15829672621
Email: 1916761005@qq.com
Country: China
ProdList: 56
Advantage: 58

Tianjin Liontec Biopharma Co.,Ltd.

Tel: 022-87601716 13920326762
Email: yzhang@liontec.com.cn
Country: China
ProdList: 61
Advantage: 58

Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd

Tel: 13801208576
Fax: 010-64215766
Email: maggie@chinazhongshuo.com
Country: China
ProdList: 77
Advantage: 65

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Shanghai Scientia Pharmaceutical Technology Co., Ltd.

Tel: 21-21-54301573 13917723525
Fax: (86)21-51861981
Email: sales@scientiapharm.com
Country: China
ProdList: 263
Advantage: 62

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Shanghai Boc Chemical Co.,Ltd

Tel: 021-34975603-808 18721111801
Fax: +86-21-34975602-805
Email: sales@bocpharma.com
Country: China
ProdList: 1009
Advantage: 64

Beijing Lunarsun Pharmaceutical Co.,LTD.

Tel: 86-10-64911848-8020.8010
Fax: 86-10-64946614
Email: sales@lunarsun.com.cn
Country: China
ProdList: 95
Advantage: 60

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7471
Advantage: 65

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Shanghai SynFarm Pharmaceutical Technology Co., Ltd.

Tel: 021-50793966 18917198199
Fax: +86-21-50793967
Email: info@synfarm.com
Country: China
ProdList: 280
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 5158
Advantage: 50

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Shenzhen HwaGen Pharmaceutical Co.,Ltd

Tel: 17722620669
Fax: 0752-5319394
Email: liangcong.yi@rafflespt.com
Country: China
ProdList: 279
Advantage: 58

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

GIHI CHEMICALS CO.,LTD

Tel: 0086-571-86217390
Fax: 0086-571-86217391
Email: Sales@gihichem.com
Country: China
ProdList: 860
Advantage: 58

DONGSHENG CHIRAL PHARMA

Tel: 15800326364 18051538752
Email: 582512789@qq.com
Country: China
ProdList: 449
Advantage: 55

Suzhou lipin Chemical Co., Ltd

Tel: 0512-0512-67509664 19888480046
Country: China
ProdList: 121
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Jiaxing Novartis Chemical Co., Ltd.

Tel: 18957373295
Fax: -
Country: China
ProdList: 1580
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

BrightGene Bio-medical Technology Co., Ltd.

Tel: 0512-0512-62551764 18013103761
Fax: 0512-62551799
Email: sales01@bright-gene.com
Country: China
ProdList: 61
Advantage: 70

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Dongyang Honsen Co., Limited

Tel: +86-0579-86846643 18072368515
Fax: +86-0579-86846643
Email: sales@honsentech.com.cn
Country: China
ProdList: 124
Advantage: 55

Credit Asia Chemical Co., Ltd.

Tel: +86 (21) 61124340
Fax: +86 (21) 6129-4103
Country: China
ProdList: 9756
Advantage: 58

BEIJING EAGLE SKY PHARMATECH CO., LTD

Tel: 010-88755821 13911359480
Email: sophia_818@126.com
Country: China
ProdList: 294
Advantage: 55

Taizhou KEDE Chemical Co., Ltd

Tel: 0576-84613060 13093829633
Fax: 0576-84613060
Email: sales@kedechemical.com
Country: China
ProdList: 299
Advantage: 60

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Guangzhou Ciming Biological Technology Co., Ltd.

Tel: 020-38082199,29065168,38082986,29878298,29866629,4000192398
Fax: +86 (20)38082986
Country: China
ProdList: 830
Advantage: 60

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 0086-15250997978
Fax: 025-58362220
Email: sale@njxizebio.com
Country: China
ProdList: 4855
Advantage: 55

Taizhou shengyu chemical co.,ltd

Tel: 0576-81816116 18969655221
Fax: 576-81816116
Email: Shengyu@shengyuchemical.com
Country: China
ProdList: 130
Advantage: 65

Intelligence Pharm Science(Shanghai) Co., Ltd.

Tel: 021-57898186
Fax: 021-37699262
Country: China
ProdList: 449
Advantage: 55

Sinfachem Limited.

Tel: 025-84683399 13952017251
Email: sinfachem@foxmail.com
Country: China
ProdList: 268
Advantage: 58

Chengdu Greenwood Technology Co., Ltd

Tel: 028-82608355
Fax: 028-82608355
Email: lvlinkeji@hotmail.com
Country: China
ProdList: 31
Advantage: 50

Chengdu DingDang Pharmaceutical Co., Ltd.

Tel: 028-86040038 13980902949;
Fax: 028-85149890
Email: market@dingdangchem.com
Country: China
ProdList: 1853
Advantage: 55

Less

View Lastest Price from 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)- 184177-83-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-11-25

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Posaconazole intermediate 184177-83-1
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 98%-101%
Supply Ability: 100 KG
Release date: 2021-05-31

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Posaconazole Impurity 71 184177-83-1
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 98%
Supply Ability: 500mg
Release date: 2024-06-28

184177-83-1, 2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-oneRelated Search:

Lercanidipine Butenafine hydrochloride Posaconazole (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Trimethoxyphenylsilane 3-Chloropropyltrimethoxysilane 3-Aminopropyltriethoxysilane Ethyl pyruvate N,N-Diisopropylethylamine N-Aminoethylpiperazine Ethylparaben Ethanol Ethyl formate Ethyl acetate Ethyl acrylate ISOXADIFEN-ETHYL Posaconazole Impurity 44 1-(4-Methoxyphenyl)piperazine

Posaconazole Diastereoisomer Related Compound 6

2S)-1-ethyl-2-bezyloxypropyl]-2

4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1

4-Triazol-3-one

ChemicalBook

1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-4-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-oneChemicalBook

Posaconazole Diastereoisomer Related Compound 7

Posaconazole Impurity 87

Posacozole Diastereoisomer Related Compound 6

Posaconazole Process Related Impurity

2-[(1S,2S)-2-benzyloxy-1-ethyl-propyl]-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol-3-one

2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one

Posaconazole int2

Posaconazole Intermediate2

1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4

Posa-O 1-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

2-(2(S)-Benzyloxy-1(S)-ethyl-propyl)-4-{4-[4-(4-hydroxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazol-3-one

4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-2-[(2S,3S)-2-phenylmethoxypentan-3-yl]-1,2,4-triazol-3-one

Posazonazole intermediate POB

2-[(1S,2S)-1-Ethyl-2-(phenylmethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one

Posaconazole side chain

[S-(R*,R*)]-2-[1-Ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one

2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]- 3H-1,2,4-Triazol-3-one,

2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]- 3H-1,2,4-triazol-3-one

2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2H-1,2,4-triazol-3(4H)-one

1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one

1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)-piperazin-1-yl)phenyl)-1H-1,2,4-tr

2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-

2-((1S,2S)-1-ethyl-2-benzyloxyl-propyl-1-yl)-2,4-diH-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-3H-1,2,4-triazol-3-one

3H-1,2,4-Triazol-3-one, 2-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-

2-(2(S)-Bezyloxy-1(S)-ethyl-propyl)-4-{4-[4-(4-hydroxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazol-3-one

Posaconazole inter-2 3H-1,2,4-Triazol-3-one,2-[(1S,2S)-1-ethyl-2-(phenylMethoxy)propyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-

2-[(1S,2S)-2-benzyloxy-1-ethyl-propyl]-4-[4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl]-1,2,4-triazol

Posaconazole Hydroxy O-Benzyl Impurity

2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]

2-((2S,3S)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2H-1,2,4-triazol-3(4H)-one (Posaconazole intermediate)

BSKZ-2

POSACONAZOLE CAS 171228-49-2 INTERMEDIATES

2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperozinyl]phenyl]-3H-1,2,4-triazol-3-one

Posaconazole Impurity 92

Posaconazole POB

2-[(1S,2S)-1-Ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-(4-...

US-DMF No.: 033194

Posaconazole synthetic intermediate

Posaconazole Intermediate 3

:2-[(1S,2S)-1-ethyl-2-bezyloxypropyl]-2,4-dihydro-4-[4-[4-Chemicalbook(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-Triazol-3-one

Side chain of Posaconazole side chain of Posaconazole

Posaconazole B

Best price and High purity supply of Posaconazole Intermediate (cas 184177-83-1)

(S),(S)2-(2-benzyloxy-1-ethyl propyl)-4-{4-[4–(4 hydroxy-phenyl)-piperzine-1-yl]-phenyl}-2,4-dihydro-[1,2,4]triazole 3 one

Posaconazole Intermediate-B

2-benzyl-1-(((2R,4R)-2-(2,4-difluorophenyl)-4-((4-(4-(4-(1-((2S,3S)-2-hydroxypentan-3-yl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phenyl)piperazin-1-yl)phenoxy)methyl)tetrahydrofuran-2-yl)methyl)-1H-1,2,4-triazol-2-ium chloride

2-[(1S,2S)-1-Ethyl-2-benzyloxypropyl]-2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazol-3-one - (posaconazole intermediate)

Anticancer agent 265

PSZ-2

1-((2S,3S)-2-(Benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one (Posaconazole Impurity)