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7BETA-HYDROXYCHOLESTEROL

Product Name
7BETA-HYDROXYCHOLESTEROL
CAS No.
566-27-8
Chemical Name
7BETA-HYDROXYCHOLESTEROL
Synonyms
7B-hydroxycholesterol;7β-hydroxycholesterol;cholest-5-en-3,7-diol;Cholest-5-ene-3,7-diol;7β-Hydrloxy Cholestero;7β-hydroxy Cholesterol;5-cholestene-3β,7β-diol;Cholesterol Impurity 29;5-CHOLESTEN-3β, 7β-DIOL;7BETA-HYDROXYCHOLESTEROL
CBNumber
CB1155521
Molecular Formula
C27H46O2
Formula Weight
402.65
MOL File
566-27-8.mol
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7BETA-HYDROXYCHOLESTEROL Property

Melting point:
165-167?C
Boiling point:
515.3±38.0 °C(Predicted)
Density 
1.03±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly)
form 
Solid
pka
14.11±0.70(Predicted)
color 
White to Off-White
InChIKey
OYXZMSRRJOYLLO-RIMZZQGGNA-N
SMILES
[C@@]12([H])CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC[C@]1([H])[C@@]3(C)CC[C@H](O)CC3=C[C@H](O)[C@@]21[H] |&1:0,4,5,13,17,19,23,28,30,r|
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Safety

Safety Statements 
22-26
WGK Germany 
-
HS Code 
29062990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H6891
Product name
7β-Hydroxycholesterol
Purity
≥95%
Packaging
1mg
Price
$191.03
Updated
2025/07/31
Sigma-Aldrich
Product number
H6891
Product name
7β-Hydroxycholesterol
Purity
≥95%
Packaging
5mg
Price
$677
Updated
2025/07/31
Cayman Chemical
Product number
20099
Product name
7β-hydroxy Cholesterol
Purity
≥98%
Packaging
1mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
20099
Product name
7β-hydroxy Cholesterol
Purity
≥98%
Packaging
5mg
Price
$571
Updated
2024/03/01
TRC
Product number
H917995
Product name
7β-HydroxyCholesterol
Packaging
1mg
Price
$160
Updated
2021/12/16
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7BETA-HYDROXYCHOLESTEROL Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

7β-hydroxycholesterol was used to study oxysterol-induced apoptosis in human endothelial cells.

Definition

ChEBI: 7beta-hydroxycholesterol is an oxysterol and a 7beta-hydroxy steroid. It is functionally related to a cholesterol.

Biological Activity

7β-Hydroxycholesterol is an oxysterol, the enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis.

IC 50

IL-1β

7BETA-HYDROXYCHOLESTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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7BETA-HYDROXYCHOLESTEROL Suppliers

Canada 1 China 115 Germany 1 India 3 Switzerland 2 United Kingdom 1 United States 17 Global 140
Chemodex Ltd.
Tel
--
Fax
--
Email
info@chemodex.com
Country
Switzerland
ProdList
1549
Advantage
50
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91

566-27-8, 7BETA-HYDROXYCHOLESTEROLRelated Search:

7-KETOCHOLESTEROL 25-HYDROXYCHOLESTEROL 5-CHOLESTEN-3-BETA, 7-ALPHA-DIOL 7BETA-HYDROXYCHOLESTEROL JC 40 22BETA-HYDROXYCHOLESTEROL 22BETA-HYDROXYCHOLESTEROL 4-BETA-HYDROXYCHOLESTEROL 7BETA-HYDROXYCHOLESTEROL-25,26,26,26,27,27,27-D7 5-CHOLESTENE Cholest-4-ene-3,6-diol, bis(hydrogen butanedioate) Cholest-4-ene-3,6-diol, bis(hydrogen butanedioate) Cholest-4-ene-3,6-diol,bis(hydrogen butanedioate) Cholest-5-ene-3,7-diol,3-butanoate,(3,7)-(9CI) Cholest-5-ene-3,7-diol,dibutanoate,(3,7)-(9CI) Cholest-4-ene-3,6-diol,(3,6)-(9CI) 5-CHOLESTEN-3-BETA, 7-BETA-DIOL DIBENZOATE JB 69

  • 7BETA-HYDROXYCHOLESTEROL
  • 3BETA,7BETA-DIHYDROXY-5-CHOLESTENE
  • 5-CHOLESTEN-3-BETA, 7-BETA-DIOL
  • 5-CHOLESTENE-3BETA,7BETA-DIOL
  • 7B-hydroxycholesterol
  • cholest-5-ene-3-beta,7-beta-diol
  • 7|beta|-Hydroxycholesterol (not deuterated)
  • 5-cholestene-3β,7β-diol
  • 7β-hydroxycholesterol
  • (3S,7R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • 7β-Hydroxycholesterol (not deuterated)
  • (3,7)-Cholest-5-ene-3,7-diol
  • 7-Hydroxycholest-5-en-3-ol
  • Cholest-5-ene-3,7-diol
  • (7R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • (7R,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • Cholest-5-ene-3,7-diol, (3b,7b)-
  • 7β-Hydrloxy Cholestero
  • cholest-5-en-3,7-diol
  • 7β-hydroxy Cholesterol
  • (3S,7R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
  • Cholesterol Impurity 29
  • 5-CHOLESTEN-3β, 7β-DIOL
  • 566-27-8
  • Anti-Proliferative Agents
  • Antitumor Agents
  • BioChemical
  • Cancer Research
  • Hydroxycholesterol
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids