PO-PRO 1

PO-PRO 1 Property

Melting point:

>250℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

Soluble in dimethyl sulfoxide

form 

powder

color 

Yellow-brown

Appearance

Blue solution

ex/em

435/455 nm

ε(extinction coefficient)

50100 cm−1M−1

Φ(quantum yield)

0.39

λmax

435 nm

Biological Applications

Nucleic acid hybridization; detecting nucleic acids; cells; nucleic acid sequencing

Hazard and Precautionary Statements (GHS)

PO-PRO 1 Chemical Properties,Usage,Production

Description

PO-TAP-1 (Oxazole Blue Monomer, also known as PO-PRO^®-1) is a blue fluorescent carbocyanine monomeric dye. PO-TAP-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.

The bright fluorescence signal and low background make PO-TAP-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments.

The dye is used to detect and count cells and microorganisms, perform nucleic acid sequencing, amplification, and hybridization, and as a temperature sensor.

Chemical Properties

Appearance: Blue solution
ex/em: 435/455 nm
Extinction coefficient (ε): 50100 cm??1M??1
Quantum yield (Φ): 0.39

Uses

Oxazole blue is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

References

[1] Sultana M, et al. A review on experimental chemically modified activated carbon to enhance dye and heavy metals adsorption[J]. Cleaner engineering and technology, 2022, 6: 100382.

Abs/Em Maxima

423 (complex)/460 (complex) nm