ChemicalBook > CAS DataBase List > Homatropine Hydrobromide

Homatropine Hydrobromide

Product Name
Homatropine Hydrobromide
CAS No.
51-56-9
Chemical Name
Homatropine Hydrobromide
Synonyms
DL-Hydrobromide;r,hbr,endo-(+-);Homatropine HBr;HoMatropineHBrUSP;Isopto Homatropine;Homatropinhydrobromid;endo-(+/-)-hydrobromid;(+-)-homatropinebromide;HOMATROPINE HYDROBROMIDE;HomatropineHydrobromideGr
CBNumber
CB1185212
Molecular Formula
C16H22BrNO3
Formula Weight
356.25
MOL File
51-56-9.mol
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Homatropine Hydrobromide Property

Melting point:
214-217 °C
storage temp. 
2-8°C
solubility 
Freely soluble in water, sparingly soluble in alcohol.
form 
Solid
color 
White to Off-White
Water Solubility 
soluble
Merck 
14,4730
CAS DataBase Reference
51-56-9(CAS DataBase Reference)
EPA Substance Registry System
Homatropine hydrobromide (51-56-9)
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Safety

Hazard Codes 
T
Risk Statements 
23/24/25
Safety Statements 
45-24/25-22
RIDADR 
1544
WGK Germany 
3
RTECS 
YM5602000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29399900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR3182
Product name
Homatropine Hydrobromide
Purity
pharmaceutical secondary standard, certified reference material
Packaging
500MG
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL84120
Product name
Homatropin hydrobromide
Purity
phyproof? Reference Substance
Packaging
50MG
Price
$262
Updated
2024/03/01
Sigma-Aldrich
Product number
BP185
Product name
Homatropine hydrobromide
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$221
Updated
2024/03/01
Cayman Chemical
Product number
30359
Product name
Homatropine (hydrobromide)
Packaging
1g
Price
$73
Updated
2024/03/01
Sigma-Aldrich
Product number
H0800000
Product name
Homatropine hydrobromide
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
h0800000
Price
$153
Updated
2024/03/01
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Homatropine Hydrobromide Chemical Properties,Usage,Production

Description

Homatropine is an anticholinergic agent. It reduces acetylcholine-induced contractions of isolated goat detrusor muscle strips when used at a concentration of 5 μM. Homatropine (1 μM) inhibits acetylcholine- or methacholine-induced contraction of isolated rat anococcygeus muscle. It inhibits serotonin- or thrombin-induced platelet aggregation in isolated sheep platelet-rich plasma (IC50s = 4.3 and 100 μM, respectively). Topical ophthalmic administration of homatropine induces partial mydriasis in Angora goats.

Chemical Properties

white crystals or crystalline powder

Uses

Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.

Uses

anticholinergic (opthalmic)

brand name

Isopto Homatropine (Alcon) .

General Description

Homatropine hydrobromide,1 H,5 H-tropan-3 -ol mandelate (ester) hydrobromide(Homatrocel), occurs as white crystals or as awhite, crystalline powder that is affected by light. It is solublein water (1:6) and alcohol (1:40), less soluble in chloroform(1:420), and insoluble in ether.
Solutions are incompatible with alkaline substances,which precipitate the free base, and with the commonreagents that precipitate alkaloids. As with atropine, solutionsare sterilized best by filtration through a bacteriologicalfilter.

Clinical Use

Homatropine hydrobromide is used topically to paralyzethe ciliary structure of the eye (cycloplegia) and to effectmydriasis. It behaves very much like atropine but is weakerand less toxic. In the eye, it acts more rapidly but less persistentlythan atropine. Dilation of the pupil takes place inabout 15 to 20 minutes, and the action subsides in about24 hours. By using a miotic, such as physostigmine, it ispossible to restore the pupil to normality in a few hours.

Homatropine Hydrobromide Preparation Products And Raw materials

Raw materials

Preparation Products

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Homatropine Hydrobromide Suppliers

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View Lastest Price from Homatropine Hydrobromide manufacturers

Shanghai Biolang Biotechnology Co., Ltd.
Product
Homatropine Hydrobromide 51-56-9
Price
US $9.90-8.80/g
Min. Order
10g
Purity
99.99%HPLC.USP42——Powder、Oil、Pills、Capsules、Tablets，Customiz
Supply Ability
1000kgs
Release date
2022-02-10
Dideu Industries Group Limited
Product
Homatropine Hydrobromide 51-56-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-27
Career Henan Chemical Co
Product
alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide 51-56-9
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

51-56-9, Homatropine HydrobromideRelated Search:

N-Acetyl-L-cysteine 4-Aminobenzoic acid Dacarbazine Serotonin hydrochloride Bromoacetyl bromide Dichloroacetic acid Cisatracurium besylate Pilocarpine nitrate Tetracaine hydrochloride Scopolamine HOMATROPINE METHYL BROMIDE Homatropine Hydrobromide Flutropium bromide Tropine HOMATROPINE Atropine tropenziline bromide (+)-HOMATROPINE METHYLBROMIDE

  • alpha-hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • MANDELYTROPINE HYDROBROMIDE
  • (+/-)-HOMATROPINE HYDROBROMIDE
  • HOMATROPINE HYDROBROMIDE
  • DL-HOMATROPINE HYDROBROMIDE
  • (+-)-homatropinebromide
  • 1-alpha-h,5-alpha-h-tropan-3-alpha-ol,mandelate(ester),hydrobromide
  • Tropine mandelate hydrobromide, DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • 1aH,5aH-Tropan-3a-ol, mandelate (ester), hydrobromide
  • Benzeneacetic acid, a-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
  • (RS)-3alpha(1alphaH,5alphaH)-Tropanylmandelat hydrobromide
  • HOMATROPINE HYDROBROMIDE(RG)
  • HoMatropineHBrUSP
  • endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide
  • 1αH,5αH-Tropan-3α-ol Mandelate (Ester) HydrobroMide
  • rac HoMatropine HydrobroMide
  • α-Hydroxybenzeneacetic Acid (3-Endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl Ester, HydrobroMide
  • DL-endo-α-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide
  • Tropine mandelate hydrobromide
  • (1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2-phenylacetate hydrobroMide
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
  • DL-Hydrobromide
  • 8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate hydrobromide
  • alpha-hydroxy-benzeneaceticaci8-methyl-8-azabicyclo(3.2.1)oct-3-yleste
  • benzeneaceticacid,alpha-hydroxy-,8-methyl-8-azabicyclo[3.2.1]oct-3-ylester,
  • endo-(+/-)-hydrobromid
  • r,hbr,endo-(+-)
  • HOMATROPINEHYDROBROMIDE,CRYSTAL,USP
  • 1αH,5αH-Tropan-3α-ol, mandelate (ester), hydrobromide (8CI)
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
  • Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-
  • Isopto Homatropine
  • Mandelic acid tropine ester hydrobromide
  • Homatropinhydrobromid
  • Homatropine HBr
  • HomatropineHydrobromideGr
  • DL-Homatropine hydrobromide, 98.5-100.5%
  • Homatropine hydrobromide CRS
  • Hyoscine hydrobromide CRS
  • Homatropine Methylbromide EP Impurity B
  • Homatropine Hydrobromide USP/EP/BP
  • dextro,laevo-homatropine hydrobromide
  • Homatropine Bromide (Homatropine hydrobromide)
  • Homatropine hydrobromide, GR 99%
  • Homatropine HydrobromideQ: What is Homatropine Hydrobromide Q: What is the CAS Number of Homatropine Hydrobromide Q: What is the storage condition of Homatropine Hydrobromide Q: What are the applications of Homatropine Hydrobromide
  • Homatropine Hydrobromide (1310008)
  • Atropine Impurity 6 HBr (Homatropine HBr)
  • DL-Homatropine hydrobromide -100gms
  • Atropine Impurity 14 HBr (Homatropine HBr)
  • 51-56-9
  • C16H21NO3HBr
  • C16H20NO3
  • C16H22NO3Br
  • Alkaloids
  • Tropane Alkaloids
  • Aromatics
  • Heterocycles
  • Inhibitors