2'-OMe-ibu-G Phosphoramidite
- Product Name
- 2'-OMe-ibu-G Phosphoramidite
- CAS No.
- 150780-67-9
- Chemical Name
- 2'-OMe-ibu-G Phosphoramidite
- Synonyms
- Cytidine Impurity 13;2’-OMe -dG(iBu) Amidite;N2-iBu-5'-O-DMT-2'-OMe-G-CE;DMT-2'-OMe-G(iBu)-CE-Admite;ibu-2'-OMe-G Phosphoramidite;2'-OMe-ibu-G Phosphoramidite;2'-OMe-G(ibu) Phosphoramidite;2’-OMe-G(ibu) Phosphoramidite;2'-OMe-rG(ibu)Phosphoramidite;2'-OMe-N-iBu Guanosine Amidite
- CBNumber
- CB11871628
- Molecular Formula
- C45H56N7O9P
- Formula Weight
- 869.94
- MOL File
- 150780-67-9.mol
2'-OMe-ibu-G Phosphoramidite Property
- Melting point:
- 138 - 140°C
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)
- form
- powder
- pka
- 9.16±0.20(Predicted)
- color
- white to off-white
- biological source
- non-animal source (no BSE/TSE risk)
- InChI
- InChI=1/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/s3
- InChIKey
- IRRDHRZUOZNWDJ-MLLDKZSOSA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- G211180
- Product name
- DMT-2′O-Methyl-rG(ib) Phosphoramidite
- Purity
- configured for PerkinElmer, configured for Polygen
- Packaging
- 1G
- Price
- $125
- Updated
- 2024/03/01
- Product number
- G211100
- Product name
- DMT-2′O-Methyl-rG(ib) Phosphoramidite
- Purity
- ≥99% (31P-NMR)
- Packaging
- 100g
- Price
- $6540
- Updated
- 2024/03/01
- Product number
- G211100
- Product name
- DMT-2′O-Methyl-rG(ib) Phosphoramidite
- Purity
- ≥99% (31P-NMR)
- Packaging
- 500g
- Price
- $31680
- Updated
- 2024/03/01
- Product number
- G211150
- Product name
- DMT-2′O-Methyl-rG(ib) Phosphoramidite
- Purity
- configured for (?KTA? and OligoPilot?)
- Packaging
- 2g
- Price
- $172
- Updated
- 2023/06/20
- Product number
- G211180
- Product name
- DMT-2′O-Methyl-rG(ib) Phosphoramidite
- Purity
- configured for PerkinElmer, configured for Polygen
- Packaging
- 0.5g
- Price
- $90.2
- Updated
- 2024/03/01
2'-OMe-ibu-G Phosphoramidite Chemical Properties,Usage,Production
Chemical Properties
The IUPAC Name is N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
Uses
2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.
Definition
2'-OMe-ibu-G Phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis. 2'-OMe-RNA CE (β-cyanoethyl) Phosphoramidites are designed to produce synthetic oligonucleotides containing nuclease resistant 2'-O-methyl ribonucleotide linkages. Deprotection, isolation and handling of 2'-O-methyl oligonucleotides are identical to the procedures for oligodeoxynucleotides.
2'-OMe-ibu-G Phosphoramidite Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2'-OMe-ibu-G Phosphoramidite manufacturers
- Product
- N2-iBu-5'-O-DMT-2'-OMe-G-CE 150780-67-9
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- ≥98%
- Supply Ability
- 20tons
- Release date
- 2023-03-09
- Product
- 5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite 150780-67-9
- Price
- US $60.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-02-10
- Product
- 2'-OMe-iBu-G CE Phosphoramidite 150780-67-9
- Price
- US $100.00/kg
- Min. Order
- 0.009999999776482582kg
- Purity
- 99%
- Supply Ability
- 5tons
- Release date
- 2023-03-20