DMT-2'-O-MOE-rU Phosphoramidite
- Product Name
- DMT-2'-O-MOE-rU Phosphoramidite
- CAS No.
- 163759-97-5
- Chemical Name
- DMT-2'-O-MOE-rU Phosphoramidite
- Synonyms
- 2'-O-MOE-U;2’-MOE-dU Amidite;5'-O-DMT-2'-O-MOE-U-CE;2'-O-MOE-UPhosphoramidite;2'-O-MOE-U Phosphoramidite;2’-MOE-rU phosphoramidite;2'-O-MOE-rU Phosphoramidite;2’-MOE-rU CE Phosphoramidite;2'-O-MOE-U-3'-phosphoramidite;2'-O-MOE-U-CE Phosphoramidite
- CBNumber
- CB22458177
- Molecular Formula
- C42H53N4O10P
- Formula Weight
- 804.86
- MOL File
- 163759-97-5.mol
DMT-2'-O-MOE-rU Phosphoramidite Property
- storage temp.
- 4°C, protect from light
- pka
- 9.39±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChIKey
- ZLOKLUONKGURQI-LWTSSKLSNA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330Rinse mouth.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M3373
- Product name
- DMT-2'-O-MOE-rU Phosphoramidite
- Packaging
- 250MG
- Price
- $68
- Updated
- 2026/03/19
- Product number
- PD64042
- Product name
- 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
- Packaging
- 50mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- PD64042
- Product name
- 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
- Packaging
- 100mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- 8732DU
- Product name
- 3-[[2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
- Packaging
- 100mg
- Price
- $212
- Updated
- 2021/12/16
- Product number
- PD64042
- Product name
- 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
DMT-2'-O-MOE-rU Phosphoramidite Chemical Properties,Usage,Production
Description
2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation.
Chemical Properties
White to Light yellow powder to crystal
Uses
2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis[1].
References
[1] Lyu F, et al. A 2'-modified uridine analog, 2'-O-(methylthiomethoxy)methyl uridine, for siRNA applications. Bioorg Med Chem Lett. 2022 Oct 15;74:128939. DOI:10.1016/j.bmcl.2022.128939
DMT-2'-O-MOE-rU Phosphoramidite Preparation Products And Raw materials
Raw materials
Preparation Products
DMT-2'-O-MOE-rU Phosphoramidite Suppliers
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View Lastest Price from DMT-2'-O-MOE-rU Phosphoramidite manufacturers
- Product
- 5'-O-DMT-2'-O-MOE-U-CE 163759-97-5
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- ≥98%
- Supply Ability
- 20tons
- Release date
- 2023-03-09
- Product
- 2'-O-MOE-U-CE Phosphoramidite 163759-97-5
- Price
- US $1100.00/g
- Min. Order
- 1g
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-02-11