2’-O-Methyl-rA(N-Bz)phosphoramidite

Product Name: 2’-O-Methyl-rA(N-Bz)phosphoramidite
CAS No.: 110782-31-5
Chemical Name: 2’-O-Methyl-rA(N-Bz)phosphoramidite
Synonyms: (2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite;Ac-dA Phosphoramidite;2’-OMe -dA(Bz) Amidite;-2-((bis(4-methoxyphenyl);2'OMe-A CE PhosphoraMidite;N6-Bz-5'-O-DMT-2'-OMe-A-CE;2'-OMe-Bz-A Phosphoramidite;Bz-2'-OMe-rA Phosphoramidite;2'-OMe-A(Bz) Phosphoramidite;2'-OMe-Bz-A Phosphoramidite
CBNumber: CB91871624
Molecular Formula: C48H54N7O8P
Formula Weight: 887.96
MOL File: 110782-31-5.mol

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2’-O-Methyl-rA(N-Bz)phosphoramidite Property

Melting point:: 93-95°C
storage temp.: Sealed in dry,2-8°C
solubility: Acetonitrile (Sparingly), DMSO (Slightly), Methanol (Slightly)
form: powder
pka: 7.87±0.43(Predicted)
color: white to off-white
InChI: InChI=1/C48H54N7O8P/c1-32(2)55(33(3)4)64(61-28-14-27-49)63-42-40(62-47(43(42)59-7)54-31-52-41-44(50-30-51-45(41)54)53-46(56)34-15-10-8-11-16-34)29-60-48(35-17-12-9-13-18-35,36-19-23-38(57-5)24-20-36)37-21-25-39(58-6)26-22-37/h8-13,15-26,30-33,40,42-43,47H,14,28-29H2,1-7H3,(H,50,51,53,56)/t40-,42-,43-,47-,64?/s3
InChIKey: AZCGOTUYEPXHMJ-DCATYJMPNA-N
SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)NC(=O)C3=CC=CC=C3)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,46,49,r|

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Safety

WGK Germany: 3
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A211180
Product name: DMT-2′O-Methyl-rA(bz) Phosphoramidite
Purity: configured for PerkinElmer, configured for Polygen
Packaging: 1G
Price: $98.7
Updated: 2024/03/01

Sigma-Aldrich

Product number: A211150
Product name: DMT-2′O-Methyl-rA(bz) Phosphoramidite
Purity: configured for (?KTA? and OligoPilot?), configured for ABI
Packaging: 2g
Price: $181
Updated: 2024/03/01

Sigma-Aldrich

Product number: A211100
Product name: DMT-2′O-Methyl-rA(bz) Phosphoramidite
Purity: ≥99% (31P-NMR)
Packaging: 100g
Price: $6540
Updated: 2024/03/01

Sigma-Aldrich

Product number: A211100
Product name: DMT-2′O-Methyl-rA(bz) Phosphoramidite
Purity: ≥99% (31P-NMR)
Packaging: 500g
Price: $32550
Updated: 2024/03/01

Sigma-Aldrich

Product number: A211180
Product name: DMT-2′O-Methyl-rA(bz) Phosphoramidite
Purity: configured for PerkinElmer, configured for Polygen
Packaging: 0.5g
Price: $92.7
Updated: 2024/03/01

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2’-O-Methyl-rA(N-Bz)phosphoramidite Chemical Properties,Usage,Production

Chemical Properties

White or off-white power

Uses

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA.

General Description

Proligo′s 2′O-Methyl RNA monomers are compatible with fast deprotectionschemes that are based on the application of aliphatic amines, such asmethylamine. The adenosine and guanosine monomers are protected bythe standard benzoyl (bz) and isobutyryl (ib) groups.2′O-Methyl RNA is a nucleic acid analog that is characterized by theexceptional hybridization properties that it imparts with complimentary DNA or RNA, as well as increased stability against enzymatic degradationcompared to natural nucleic acids.The unique combination of properties of 2′O-Methyl RNA had foundwidespread use in the fields of:
Diagnostic probes
Aptamer and ribozyme development
Mixed 2′O-Methyl-RNA/DNA antisense molecules

2’-O-Methyl-rA(N-Bz)phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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2’-O-Methyl-rA(N-Bz)phosphoramidite Suppliers

China 147 India 4 United Kingdom 2 United States 11 Global 164

Nugene Biopharm Science (Hangzhou) Co., Ltd.

Tel: 13326014885
Email: service@nugene.com.cn
Country: China
ProdList: 51
Advantage: 58

Shanghai Peinuo Biotechnology Co., Ltd

Tel: 021-58648778 18217200601
Fax: QQ:99286241
Email: bush@perno.cn
Country: China
ProdList: 292
Advantage: 58

Wuhu Nuowei Chemical Technology Co., Ltd

Tel: 0553-8233716 18055326116
Email: kendoll@cqpharm.com
Country: China
ProdList: 647
Advantage: 58

Nanjing F&S Pharmatech Co., Ltd.

Tel: 025-86950358 13390612682
Email: wangjinyu@fshpharm.com
Country: China
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Nanjing GoodGene Biotechnology Co., Ltd

Tel: 13335632219
Email: 3152731197@qq.com
Country: China
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Shanghai Bolu Biotechnology Co., Ltd

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Email: 3662942976@QQ.com
Country: China
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Wuhu Huaren Science and Technology Co., Ltd.

Tel: 0553-0553-5842013-801 18155347026
Fax: 086-553-5843138
Email: sale@huarensh.com
Country: China
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Hefei Huana Biomedical Technology Co.,Ltd

Tel: 17333066501
Email: shengwen.fang@huanaok.com.cn
Country: China
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Hongene Biotech Corporation

Tel: 021-64757213
Fax: 86-21-64700613
Email: info@hongene.com
Country: China
ProdList: 672
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

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View Lastest Price from 2’-O-Methyl-rA(N-Bz)phosphoramidite manufacturers

SHANGHAI NOVRIBO BIOTECH

Product: 2'-OMe-Bz-A CE Phosphoramidite 110782-31-5
Price: US $100.00/kg
Min. Order: 0.009999999776482582kg
Purity: 99%
Supply Ability: 5tons
Release date: 2023-03-21

Hefei Huana Biomedical Technology Co.,Ltd.

Product: N6-Bz-5'-O-DMT-2'-OMe-A-CE 110782-31-5
Price: US $0.00/mg
Min. Order: 100mg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2023-03-09

Henan Aochuang Chemical Co.,Ltd.

Product: 2’-O-Methyl-rA(N-Bz)phosphoramidite 110782-31-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-23

110782-31-5, 2’-O-Methyl-rA(N-Bz)phosphoramiditeRelated Search:

DMT-dG(dmf) Phosphoramidite DMT-2′O-Methyl-rC(ac) Phosphoramidite 2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-MOE-A(Bz)-3'-phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-(2-Methoxyethyl)cytidine 2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite 2'-O-(2-Methoxyethyl)guanosine 2'-O-Methyladenosine

2’-O-Methyl-rA(N-Bz)phosphoramidite

N-blocked-5'-O-DMT-2'-O-Me CED adenosine phosphoramidite

5'-O-DMT-2'-O-Me-rA(N-Bz)-3'-CEDPA

N-Benzoyl-5'-O-(4,4-dimethoxytrityl)-2'-O-methyladenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

2'-OMe-Bz-A Phosphoramidite

Ac-dA Phosphoramidite

5'-O-DMT-2'-O-Me-A(bz) phosphoramidite

2'OMe-A CE PhosphoraMidite

5'-DiMethoxytrityl-N-benzoyl-Adenosine,2'-O-Methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoraMidite

N6-Benzoyl-5'-O-DMT-2'-O-methyl-D-adenosine 3'-CE phosphoramidite

DMT-2′O-Methyl-rA(bz) Phosphoramidite

2'-O-Methyl-N6-Benzoyl-5'-O-DMT-Adenosine-3'-CE-Phosphoramidite

5'-DMT-2'-OMe-rA(N-Bz) Phosphoramidite

(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

-2-((bis(4-methoxyphenyl)

-4-methoxytetrahydrofuran-3-yl (2-cyanoethyl)

-5-(6-Benzamido-9H-purin-9-yl)

N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl adenosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphoramidite

N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine 3'-CE phosphoramidite

N-[9-(5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-4-{[(2-CYANOETHOXY)(DIISOPROPYLAMINO)PHOSPHANY

2'-OMe-Bz-rA -CE Phosphoramidite

Bz-2'-OMe-rA Phosphoramidite

N6-benzoyl-5'-O-(4, 4'-Dimethoxytrityl)-2'-O-methyl-Adenosine-3'-CE-Phosphoramidite

2'-O-methyladenosine-ce phosphoramidite for abi

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

2'-OMe-A(Bz) Phosphoramidite

5'-O-DMT-2'-OMe-Bz-A-CE-Phosphoramidite

DMT-2'-OME-dA(Bz)-CE-Phosphoramidite

DMT-2-OMe-A (Bz) Phosphoramidite

5'-DMTr-2'-O-Me-N6Bz-3'-O-CEP-ADENOSINE

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-methoxyoxolan-2-yl]purin-6-yl]benzamide

5'-O-DMT-N6-Benzoyl-2'-O-methyladenosine 3'-CE phosphoramidite

5'-O-DMT-2'-OMe-Benzoyl-Adenosine-CE Phosphoramidite

DMT-2-O-ME-A-CE Phosphoramidite

N6-Bz-5'-O-DMT-2'-OMe-A-CE

DMT-2’-OMe-A(Bz)-CE Phosphoramidite

5'-O-DMT-2'-OMe-N6-Benzoyl -Adenosine-3’-Cyanoethyl Phosphoramidite

2'-OMe-N-Bz Adenosine Amidite

DMTr-2'-O-Me-rA(Bz)-3'-CE-Phosphoramidite

2’-OMe -dA(Bz) Amidite

5'-ODMT-2'-OMe-N-Bz Adenosine-3'-OCEPA

2’-O-Methyl-rA(N-Bz)phosphoramidite

2'-OMe-Bz-A Phosphoramidite

DMT-2'-O-Me-A(Bz)-CE Phosphoramidite

DMT-2'-O-methyl-rA(Bz) Phosphoramidite

5'-O-DMT-2'-OMe-Benzoyl-Adenosine-CE Phosphoramidite

110782-31-5

Amidite