2'-O-MOE-A(Bz)-3'-phosphoramidite

Product Name: 2'-O-MOE-A(Bz)-3'-phosphoramidite
CAS No.: 251647-53-7
Chemical Name: 2'-O-MOE-A(Bz)-3'-phosphoramidite
Synonyms: DMT-2'-O-MOE-A(Bz)-CE;2’-MOE-dA(Bz) Amidite;N6-Bz-5'-O-DMT-2'-O-MOE-A-CE;2'-O-MOE-Bz-A Phosphoramidite;2'-MOE-N-Bz Adenosine Amidite;2'-MOE-Bz-A CE Phosphoramidite;2'-O-MOE-rA(Bz) Phosphoramidite);2'-O-MOE-A(Bz)-CE Phosphoramidite;2'-O-MOE-A(Bz)-3'-phosphoramidite;2'-O-MOE-A(Bz)-3'-phosphoramidite
CBNumber: CB83051689
Molecular Formula: C50H58N7O9P
Formula Weight: 932.01
MOL File: 251647-53-7.mol

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2'-O-MOE-A(Bz)-3'-phosphoramidite Property

pka: 7.87±0.43(Predicted)
InChI: InChI=1/C50H58N7O9P/c1-34(2)57(35(3)4)67(64-28-14-27-51)66-44-42(31-63-50(37-17-12-9-13-18-37,38-19-23-40(60-6)24-20-38)39-21-25-41(61-7)26-22-39)65-49(45(44)62-30-29-59-5)56-33-54-43-46(52-32-53-47(43)56)55-48(58)36-15-10-8-11-16-36/h8-13,15-26,32-35,42,44-45,49H,14,28-31H2,1-7H3,(H,52,53,55,58)/t42-,44-,45-,49-,67?/s3
InChIKey: VPBYBQBHLYRLHG-VCCSSPGHNA-N
SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)NC(=O)C3=CC=CC=C3)N=C2)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,46,52,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B207938
Product name: N6-Benzoyl-5''-O-DMT-2''-O-(2-methoxyethyl)adenosine3''-CEPhosphoramidite
Packaging: 50mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB59569
Product name: N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
Packaging: 250mg
Price: $90
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB59569
Product name: N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
Packaging: 500mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB59569
Product name: N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
Packaging: 1g
Price: $275
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PB59569
Product name: N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite
Packaging: 2g
Price: $500
Updated: 2021/12/16

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2'-O-MOE-A(Bz)-3'-phosphoramidite Chemical Properties,Usage,Production

Description

2'-O-MOE-A(Bz)-3'-phosphoramidite, also known as DMT-2'-O-MOE-rA(Bz) phosphoramidite, inserts 2'-O-methoxyethyl-modified adenosine into oligonucleotide phosphoramidites for antisense RNA. Its 2'-MOE backbone bolsters duplex stability, nuclease resistance, and has low toxicity, contributing to effective, safe genetic manipulation. It is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

Chemical Properties

The IUPAC name of 2'-O-MOE-A(Bz)-3'-phosphoramidite is (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(2-methoxyethoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. It is white to off-white powder.

Uses

N6-Benzoyl-5''-O-DMT-2''-O-(2-methoxyethyl)adenosine 3''-CE phosphoramidite (CAS# 251647-53-7) is used diagnostically in the screening of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) oligonucleotidic modulators.

2'-O-MOE-A(Bz)-3'-phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-MOE-A(Bz)-3'-phosphoramidite Suppliers

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Zhengzhou Granlen Sciences, ltd.

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View Lastest Price from 2'-O-MOE-A(Bz)-3'-phosphoramidite manufacturers

SHANGHAI NOVRIBO BIOTECH

Product: 2'-MOE-Bz-A CE Phosphoramidite 251647-53-7
Price: US $100.00/kg
Min. Order: 0.009999999776482582kg
Purity: 99%
Supply Ability: 5tons
Release date: 2023-03-20

Hefei Huana Biomedical Technology Co.,Ltd.

Product: N6-Bz-5'-O-DMT-2'-O-MOE-A-CE 251647-53-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2023-03-09

251647-53-7, 2'-O-MOE-A(Bz)-3'-phosphoramiditeRelated Search:

2'-O-Methylcytidine DMT-2μ-O-Me-rG(ib) amidite 2’-O-Methyl-rA(N-Bz)phosphoramidite DMT-2′Fluoro-dU Phosphoramidite 2'-O-(2-Methoxyethyl)-5-methyluridine N-blocked-5'-O-DMT-2'-O-Me CED cytosine phosphoramidite N4-Benzoyl-5'-O-DMT-2'-O-methyl-5-methylcytidine 3'-CE phosphoramidite Dmt-2'-f-dc(ac) amidite 2'-O-Methyladenosine 2'-O-(2-Methoxyethyl)cytidine 2'-O-Methylguanosine 2'-O-(2-Methoxyethyl)uridine DMT-2'-O-MOE-rU Phosphoramidite 2'-O-MOE-ADENOSINE 2'-OMe-ibu-G Phosphoramidite 2'-O-(2-Methoxyethyl)guanosine

2'-O-MOE-A(Bz)-3'-phosphoramidite

N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite

2'-O-MOE-A(Bz)-CE Phosphoramidite

ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI)

2'-O-MOE-Bz-A Phosphoramidite

5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-ME-A(BZ) PHOSPHORAMIDITE

DMT-2'-O-MOE-A(Bz)-CE-Phosphoramidite

N6-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-O-methoxyethyl-adenosine-3'-cyanoethyl Phosphoramidite

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite

2'-O-MOE-rA(Bz) Phosphoramidite)

5'-O-DMT-N6-Benzoyl-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite

Adenosine,N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite

5'-O-(4,4'-Dimethoxytrityl)-2'-O-methoxyethyl-N6-benzoyl-adenosine -3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite

5'-DMTr-2'-MOE-N6-Bz-3'-CEP-Adenosine

5'-DMTr-2'-MOE-N6Bz-3'-O-CEP-ADENOSINE

DMT-2′O-MOE-rA(bz) Phosphoramidite

2’-O-MOE-A(Bz)-3’-phospho ramidite, N6-Benzoyl-5’-O-(4,4’-dimethoxy-trityl)-2’-O-(2-methoxyethyl)adeno sine-3’-O-[(2-cyanoethyl)(N,N-diisopropyl)]-phosphorramidite

N6-Bz-5’-O-DMTr-2’-O-(2-methoxyethyl)-adenosine-3’-CED-phosphoramidite

N6-Bz-5'-O-DMT-2'-O-MOE-A-CE

5'-O-DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite

2'-MOE-Bz-A CE Phosphoramidite

5'-O-DMT-2'-O-MOE-N6-Benzoyl- Adenosine -3’-Cyanoethyl Phosphoramidite

2'-MOE-N-Bz Adenosine Amidite

DMT-2'-O-MOE-A(Bz)-CE

DMTr-2'-O-MOE-rA(Bz)-3'-CE-Phosphoramidite

2’-MOE-dA(Bz) Amidite

N6-Benzoyl-2-o-methyladenosine 3-ce phosphoramidite

N6-Benzoyl-5’-O-(4, 4’-dimethoxytrityl)-2’-O-(2-methoxyethyl)adenosine-3’-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

5'-ODMT-2'-OMOE-N-Bz Adenosine-3'-OCEPA

2'-O-MOE-A(Bz)-3'-phosphoramidite

DMT-2'-O-MOE-A(Bz)-CE Phosphoramidite

251647-53-7

C50H58N7O9P

Amidite