ChemicalBook > CAS DataBase List > DMT-2'-O-MOE-rU Phosphoramidite

DMT-2'-O-MOE-rU Phosphoramidite

Product Name: DMT-2'-O-MOE-rU Phosphoramidite
CAS No.: 163759-97-5
Chemical Name: DMT-2'-O-MOE-rU Phosphoramidite
Synonyms: 2'-O-MOE-U;2’-MOE-dU Amidite;5'-O-DMT-2'-O-MOE-U-CE;2'-O-MOE-UPhosphoramidite;2'-O-MOE-U Phosphoramidite;2'-O-MOE-rU Phosphoramidite;2'-O-MOE-U-3'-phosphoramidite;2'-O-MOE-U-CE Phosphoramidite;2’-O-MOE-U-3’-phosphoramidite;2'-O-MOE-U-CE-Phosphoramidite
CBNumber: CB22458177
Molecular Formula: C42H53N4O10P
Formula Weight: 804.86
MOL File: 163759-97-5.mol

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DMT-2'-O-MOE-rU Phosphoramidite Property

storage temp.: 4°C, protect from light
form: Solid
pka: 9.39±0.10(Predicted)
color: White to off-white
InChI: InChI=1/C42H53N4O10P/c1-29(2)46(30(3)4)57(54-25-11-23-43)56-38-36(55-40(39(38)52-27-26-49-5)45-24-22-37(47)44-41(45)48)28-53-42(31-12-9-8-10-13-31,32-14-18-34(50-6)19-15-32)33-16-20-35(51-7)21-17-33/h8-10,12-22,24,29-30,36,38-40H,11,25-28H2,1-7H3,(H,44,47,48)/t36-,38-,39-,40-,57?/s3
InChIKey: ZLOKLUONKGURQI-LWTSSKLSNA-N
SMILES: O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: M3373
Product name: DMT-2'-O-MOE-rU Phosphoramidite
Packaging: 250MG
Price: $103
Updated: 2025/07/31

Biosynth Carbosynth

Product number: PD64042
Product name: 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
Packaging: 100mg
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: 8732DU
Product name: 3-[[2-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(2,4-dioxopyrimidin-1-yl)-4-(2-methoxyethoxy)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Packaging: 100mg
Price: $212
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD64042
Product name: 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
Packaging: 250mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD64042
Product name: 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite
Packaging: 500mg
Price: $350
Updated: 2021/12/16

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DMT-2'-O-MOE-rU Phosphoramidite Chemical Properties,Usage,Production

Description

2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation.

Chemical Properties

White to Light yellow powder to crystal

Uses

2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis[1].

References

[1] Lyu F, et al. A 2'-modified uridine analog, 2'-O-(methylthiomethoxy)methyl uridine, for siRNA applications. Bioorg Med Chem Lett. 2022 Oct 15;74:128939. DOI:10.1016/j.bmcl.2022.128939

DMT-2'-O-MOE-rU Phosphoramidite Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from DMT-2'-O-MOE-rU Phosphoramidite manufacturers

Hefei Huana Biomedical Technology Co.,Ltd.

Product: 5'-O-DMT-2'-O-MOE-U-CE 163759-97-5
Price: US $0.00/mg
Min. Order: 100mg
Purity: ≥98%
Supply Ability: 20tons
Release date: 2023-03-09

R&D Scientific Inc.

Product: 2'-O-MOE-U-CE Phosphoramidite 163759-97-5
Price: US $1100.00/g
Min. Order: 1g
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-02-11

163759-97-5, DMT-2'-O-MOE-rU PhosphoramiditeRelated Search:

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(2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-(2-METHOXYETHOXY)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite

5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite

2'-O-MOE-U-CE Phosphoramidite

2'-O-MOE-U-3'-phosphoramidite

2'-O-MOE-U Phosphoramidite

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)

5'-O-DMT-2'-(2-methoxyethyl)uridine 3'-CE phosphoramidite

5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-uridine-3'-cyanoethyl Phosphoramidite

DMT-2'-O-MOE-U-CE-Phosphoramidite

2'-O-MOE-rU Phosphoramidite

2'-O-MOE-U

5'-O-DMT-2'-O-MOE-U-CE

5’-O-DMTr-2’-O-MOE-U-3’-phosphoramidite

2’-MOE-dU Amidite

DMT-2'-O-MOE-rU Phosphoramidite

5'-ODMT-2'-OMOE Uridine-3'-OCEPA

2’-O-MOE-U-3’-phosphoramidite

2'-O-MOE-UPhosphoramidite

2'-O-MOE-U-CE-Phosphoramidite

3-[({[(2R,3R,4R,5R)-2-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-(2-methoxyethoxy)oxolan-3-yl]oxy}(bis(propan-2-yl)amino)phosphanyl)oxy]propanenitrile

5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)uridine

163759-97-5

C42H53N4O10P

Phosphoramidite