1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Product Name
- 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- CAS No.
- 52691-62-0
- Chemical Name
- 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
- Synonyms
- LYSO-PAF16;1-hexadecyl;C16 LYSO PAF;LYSO-PAF (C16);Lyso-PAF (C16),98%;FITC-Lyso-PAF C-16;LYSO-PLATELET ACTIVATING FACTOR;LYSO-PLATELET ACTIVATING FACTOR-16;LYSO-PLATELET ACTIVATING FACTOR (C16);1-O-Alkyl-sn-glycero-3-phosphocholine
- CBNumber
- CB1188420
- Molecular Formula
- C24H52NO6P
- Formula Weight
- 481.65
- MOL File
- 52691-62-0.mol
1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property
- Melting point:
- >240 °C
- storage temp.
- −20°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
- form
- A lyophilized powder
- pka
- 1.209±0.50(predicted)
- color
- White to off-white
- biological source
- synthetic
- CAS DataBase Reference
- 52691-62-0
N-Bromosuccinimide Price
- Product number
- L5016
- Product name
- 1-O-Palmityl-sn-glycero-3-phosphocholine
- Purity
- ≥99%, synthetic
- Packaging
- 1mg
- Price
- $184
- Updated
- 2025/07/31
- Product number
- L5016
- Product name
- 1-O-Palmityl-sn-glycero-3-phosphocholine
- Purity
- ≥99%, synthetic
- Packaging
- 10mg
- Price
- $686
- Updated
- 2025/07/31
- Product number
- 60906
- Product name
- Lyso-PAF C-16
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 60906
- Product name
- Lyso-PAF C-16
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 60906
- Product name
- Lyso-PAF C-16
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $36
- Updated
- 2024/03/01
1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production
Description
Lyso-
Chemical Properties
white solid
Uses
Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16, or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine. Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.
Uses
Lyso-PAF C-16 is an inactive platelet activating factor (PAF).
Definition
ChEBI: Lysophosphatidylcholine O-16:0/0:0 is a lysophosphatidylcholine O-16:0e in which the hexadecyl group at C-1 contains 16 carbons of which none are unsaturated. It has a role as a metabolite. It is a lysophosphatidylcholine O-16:0 and a 1-alkyl-sn-glycero-3-phosphocholine.
References
[1] D M STAFFORINI L W T. Human plasma platelet-activating factor acetylhydrolase.[J]. Methods in molecular biology, 1999, 109: 49-58. DOI: 10.1385/1-59259-581-2:49
[2] Y. UEMURA F S T Lee. A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway.[J]. The Journal of Biological Chemistry, 1991, 50 1: 8268-8272. DOI: 10.1016/s0021-9258(18)92972-8
[3] M E VENABLE. Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophils.[J]. The Journal of Biological Chemistry, 1991, 266 28: 18691-18698.
[4] K DEGUCHI A D S Murashima. [Platelet activating factor].[J]. Nihon rinsho. Japanese journal of clinical medicine, 1987, 45 5: 1115-1126.
[5] M. VENABLE. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation.[J]. The Journal of Biological Chemistry, 1993, 49 1: 7965-7975. DOI: 10.1016/s0021-9258(18)53052-0
1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials
Raw materials
Preparation Products
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