ChemicalBook > CAS DataBase List > 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE

1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Product Name
1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS No.
52691-62-0
Chemical Name
1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Synonyms
LYSO-PAF16;1-hexadecyl;C16 LYSO PAF;LYSO-PAF (C16);Lyso-PAF (C16),98%;FITC-Lyso-PAF C-16;LYSO-PLATELET ACTIVATING FACTOR;LYSO-PLATELET ACTIVATING FACTOR-16;LYSO-PLATELET ACTIVATING FACTOR (C16);1-O-Alkyl-sn-glycero-3-phosphocholine
CBNumber
CB1188420
Molecular Formula
C24H52NO6P
Formula Weight
481.65
MOL File
52691-62-0.mol
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1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

Melting point:
>240 °C
storage temp. 
−20°C
solubility 
DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 10 mg/ml; Water: 20 mg/ml
form 
A lyophilized powder
pka
1.209±0.50(predicted)
color 
White to off-white
biological source
synthetic
CAS DataBase Reference
52691-62-0
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
F 
10-21
HS Code 
33011300
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L5016
Product name
1-O-Palmityl-sn-glycero-3-phosphocholine
Purity
≥99%, synthetic
Packaging
1mg
Price
$184
Updated
2025/07/31
Sigma-Aldrich
Product number
L5016
Product name
1-O-Palmityl-sn-glycero-3-phosphocholine
Purity
≥99%, synthetic
Packaging
10mg
Price
$686
Updated
2025/07/31
Cayman Chemical
Product number
60906
Product name
Lyso-PAF C-16
Purity
≥98%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
60906
Product name
Lyso-PAF C-16
Purity
≥98%
Packaging
10mg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
60906
Product name
Lyso-PAF C-16
Purity
≥98%
Packaging
1mg
Price
$36
Updated
2024/03/01
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1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Description

Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16, or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine. Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.

Chemical Properties

white solid

Uses

Lyso-PAF C-16 can be formed by either the action of PAF-AH on PAF C-16, or by the action of a CoA-independent transacylase on 1-O-hexadecyl-2-acyl-glycerophosphocholine. Lyso-PAF C-16 is a substrate for either PAF C-16 formation by the remodeling pathway or selective acylation with arachidonic acid by a CoA-independent transacylase.

Uses

Lyso-PAF C-16 is an inactive platelet activating factor (PAF).

Definition

ChEBI: Lysophosphatidylcholine O-16:0/0:0 is a lysophosphatidylcholine O-16:0e in which the hexadecyl group at C-1 contains 16 carbons of which none are unsaturated. It has a role as a metabolite. It is a lysophosphatidylcholine O-16:0 and a 1-alkyl-sn-glycero-3-phosphocholine.

References

[1] D M STAFFORINI  L W T. Human plasma platelet-activating factor acetylhydrolase.[J]. Methods in molecular biology, 1999, 109: 49-58. DOI: 10.1385/1-59259-581-2:49
[2] Y. UEMURA F S T Lee. A coenzyme A-independent transacylase is linked to the formation of platelet-activating factor (PAF) by generating the lyso-PAF intermediate in the remodeling pathway.[J]. The Journal of Biological Chemistry, 1991, 50 1: 8268-8272. DOI: 10.1016/s0021-9258(18)92972-8
[3] M E VENABLE. Conversion of 1-O-[3H]alkyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine to lyso platelet-activating factor by the CoA-independent transacylase in membrane fractions of human neutrophils.[J]. The Journal of Biological Chemistry, 1991, 266 28: 18691-18698.
[4] K DEGUCHI  A D  S Murashima. [Platelet activating factor].[J]. Nihon rinsho. Japanese journal of clinical medicine, 1987, 45 5: 1115-1126.
[5] M. VENABLE. Enzymatic studies of lyso platelet-activating factor acylation in human neutrophils and changes upon stimulation.[J]. The Journal of Biological Chemistry, 1993, 49 1: 7965-7975. DOI: 10.1016/s0021-9258(18)53052-0

1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE Suppliers

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52691-62-0, 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINERelated Search:

1,2-DIHEPTADECANOYL-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE 1-O-OCTADECYL-2-O-METHYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIHEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE DIHYDRATE 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIEICOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE L-ALPHA-LYSOPHOSPHATIDYLCHOLINE phosphorylcholine 1-O-HEXADECYL-2-ARACHIDONYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE PAF (C18) 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIDOCOSANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE POPC 1-O-HEXADECYL-2-O-METHYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1-PALMITOYL-2-PYRENEDECANOYLPHOSPHATIDYLCHOLINE

  • 1-O-hexadecyl-2-lyso-glycero-3-phosphorylcholine
  • GAMMA-O-HEXADECYL L-A-LYSOPHOSPHATIDYLCHOLINE
  • 1-Hexadecyl-sn-glycero-3-phosphocholine, 3-sn-Lysophosphatidylcholine, 1-hexadecyl, Lyso-PAF-C16, Lyso-platelet activating factor
  • 1-O-Alkyl-sn-glycero-3-phosphocholine, Lyso-platelet activating factor
  • γ-O-Alkyl-L-α-lysophosphatidylcholine from bovine heart
  • Lyso-PAF (C16),98%
  • 1-hexadecyl
  • 3-sn-Lysophosphatidylcholine, 1-hexadecyl
  • 1-O-Alkyl-sn-glycero-3-phosphocholine
  • 1-O-HEXADECYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE;C16 LYSO PAF
  • LYSO-PLATELET ACTIVATING FACTOR (C16)
  • LYSO-PAF16
  • LYSO-PAF (C16)
  • LYSO-PLATELET ACTIVATING FACTOR
  • LYSO-PLATELET ACTIVATING FACTOR-16
  • L-ALPHA-PHOSPHATIDYLCHOLINE-GAMMA-O-HEXADECYL
  • L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, GAMMA-O-HEXADECYL
  • C16 LYSO PAF
  • 1-O-PALMITYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE
  • 1-O-HEXADECYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE
  • 1-O-HEXADECYL-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
  • LYSO PAF[C16] (L-A-LYSOPHOSPHATIDYLCHOLI NBE, GAMMA-O-HEXADECYL)
  • L-A-LYSOPHOSPHATIDYLCHOLINE, GAMMA-O-*HE XADECYL
  • L -ALPHA-LYSOPHOSPHATIDYL- CHOLINE-GAMMA-O-HEXADECYL 99%
  • 1-hexadecyl-sn-glycero-3-phosphocholine
  • (R)-3-(Hexadecyloxy)-2-hydroxypropyl (2-(trimethylammonio)ethyl) phosphate
  • 1-Heaxadecyl-2-Hydroxy-sn-Glycero-3-Phosphocholine
  • 1-O-Palmityl-sn-glycero-3-phosphocholine >=99%, synthetic
  • 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4,7-dihydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-
  • 1-O-Palmityl-<i>sn</i>-glycero-3-phosphocholine
  • FITC-Lyso-PAF C-16
  • 52691-62-0
  • C24H52NO6P
  • Biochemicals and Reagents
  • BioChemical
  • Glycerophosphonocholines
  • Glycerides
  • Phosphoglycerides
  • Lipids