3-Amino-3-(4-methoxyphenyl)propionic acid
- Product Name
- 3-Amino-3-(4-methoxyphenyl)propionic acid
- CAS No.
- 5678-45-5
- Chemical Name
- 3-Amino-3-(4-methoxyphenyl)propionic acid
- Synonyms
- 3-AMINO-3-(4-METHOXYPHENYL)PROPANOIC ACID;CL030;RARECHEM AK HC T257;DL--(p-Methoxyphenyl)alanine;DL-BETA-(P-METHOXYPHENYL)ALANINE;3-(P-METHOXYPHENYL)-DL-BETA-ALANINE;3-ami-3-(4-methoxyphenyl)propaic acid;Benzenepropanoicacid,β-aMino-4-Methoxy-;3-AMINO-3-(4-METHOXYPHENYL)PROPIONIC AC&;3-AMINO-3-(P-METHOXYPHENYL)PROPIONIC ACID
- CBNumber
- CB1203354
- Molecular Formula
- C10H13NO3
- Formula Weight
- 195.22
- MOL File
- 5678-45-5.mol
3-Amino-3-(4-methoxyphenyl)propionic acid Property
- Melting point:
- 230 °C (dec.)(lit.)
- Boiling point:
- 331.88°C (rough estimate)
- Density
- 1.1926 (rough estimate)
- refractive index
- 1.5150 (estimate)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to crystal
- pka
- 3.74±0.10(Predicted)
- color
- White to Almost white
- CAS DataBase Reference
- 5678-45-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2532
- Product name
- 3-Amino-3-(4-methoxyphenyl)propionic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $135
- Updated
- 2025/07/31
- Product number
- A2532
- Product name
- 3-Amino-3-(4-methoxyphenyl)propionic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $408
- Updated
- 2025/07/31
- Product number
- A612083
- Product name
- 3-Amino-3-(4-methoxyphenyl)propanoicAcid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AK-43943
- Product name
- 3-Amino-3-(4-methoxyphenyl)propanoicacid
- Purity
- 97%
- Packaging
- 1g
- Price
- $31
- Updated
- 2021/12/16
- Product number
- 016487
- Product name
- 3-Amino-3-(4-methoxyphenyl)propanoic acid
- Packaging
- 500mg
- Price
- $33
- Updated
- 2021/12/16
3-Amino-3-(4-methoxyphenyl)propionic acid Chemical Properties,Usage,Production
Chemical Properties
white to beige crystalline powder
Synthesis
141-82-2
123-11-5
5678-45-5
To a 150 mL round bottom flask was added 28.5 g (0.21 mol) of p-methoxybenzaldehyde, 21.8 g (0.21 mol) of malonic acid and 32.3 g (0.42 mol) of ammonium acetate dissolved in 150 mL of ethanol. The reaction mixture was heated to 75-80°C and the reaction was stirred under reflux conditions for 8 hours. Upon completion of the reaction, the reaction mixture was cooled to room temperature and stirring was continued for 20 hours. Subsequently, a white solid was collected by filtration to afford 23.6 g of 3-amino-3-(4-methoxyphenyl)propionic acid (racemic mixture) in 82.3% yield (based on p-methoxybenzaldehyde). The product was a white powder and its physical properties were as follows: 1H-NMR (δ, ppm, D2O): 2.50 (dd, 1H, J = 17.1, 6.8 Hz), 2.65 (dd, 1H, J = 17.1, 7.8 Hz), 3.24 (s, 3H), 6.46 (s, 1H), 6.48 (s, 1H), 6.86 (s, 1H), 6.88 (s, 1H); 13C-NMR (δ, ppm, D2O): 37.1, 50.7, 55.1, 114.3, 126.9, 128.2, 159.1, 172.7; MS (EI) m/z: 195 (M+); MS (CI, i-C4H10) m/z: 196 (MH+).
References
[1] Patent: EP1621529, 2006, A1. Location in patent: Page/Page column 40
[2] Chemical Communications, 2011, vol. 47, # 20, p. 5894 - 5896
[3] Journal of Medicinal Chemistry, 2001, vol. 44, # 12, p. 1938 - 1950
[4] Advanced Synthesis and Catalysis, 2010, vol. 352, # 2-3, p. 395 - 406
[5] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 252 - 268
3-Amino-3-(4-methoxyphenyl)propionic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Amino-3-(4-methoxyphenyl)propionic acid Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Country
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View Lastest Price from 3-Amino-3-(4-methoxyphenyl)propionic acid manufacturers
- Product
- 3-Amino-3-(4-methoxyphenyl)propionic acid 5678-45-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19
- Product
- 3-Amino-3-(4-methoxyphenyl)propionic acid 5678-45-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 3-Amino-3-(4-methoxyphenyl)propionic acid 5678-45-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25