2-(Trifluoromethyl)benzenesulfonamide

Product Name: 2-(Trifluoromethyl)benzenesulfonamide
CAS No.: 1869-24-5
Chemical Name: 2-(Trifluoromethyl)benzenesulfonamide
Synonyms: BUTTPARK 91\08-54;Tritosulfuron Metabolite BH635-2;2-(Trifluoromethyl)benzenesulfomide;2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE;2-(TRIFLUOROMETHYL)BENZENESULPHONAMIDE;BenzenesulfonaMide, 2-(trifluoroMethyl)-;(2-Trifluoromethylphenyl)-methanesulfonamide;2-(Trifluoromethyl)benzenesulfonamide ISO 9001：2015 REACH
CBNumber: CB1211601
Molecular Formula: C7H6F3NO2S
Formula Weight: 225.19
MOL File: 1869-24-5.mol

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2-(Trifluoromethyl)benzenesulfonamide Property

Melting point:: 180-184 °C(lit.)
Boiling point:: 320.5±52.0 °C(Predicted)
Density: 1.482±0.06 g/cm3(Predicted)
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 9.55±0.60(Predicted)
color: White to Almost white
BRN: 2697078
CAS DataBase Reference: 1869-24-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 22
Safety Statements: 22-24/25-36
RIDADR: 2811
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: I
HS Code: 29350090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 563552
Product name: 2-(Trifluoromethyl)benzenesulfonamide
Purity: 97%
Packaging: 1g
Price: $41.8
Updated: 2023/06/20

TCI Chemical

Product number: T3368
Product name: 2-(Trifluoromethyl)benzenesulfonamide
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $52
Updated: 2025/07/31

TCI Chemical

Product number: T3368
Product name: 2-(Trifluoromethyl)benzenesulfonamide
Purity: >98.0%(HPLC)(N)
Packaging: 25g
Price: $160
Updated: 2025/07/31

TRC

Product number: T797153
Product name: 2-(Trifluoromethyl)benzenesulfonamide
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Matrix Scientific

Product number: 024671
Product name: 2-(Trifluoromethyl)benzenesulfonamide
Purity: 97%
Packaging: 25g
Price: $79
Updated: 2021/12/16

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2-(Trifluoromethyl)benzenesulfonamide Chemical Properties,Usage,Production

Chemical Properties

Pale yellow to off-white crystalline powder

Synthesis

776-04-5

1869-24-5

General procedure for the synthesis of o-(trifluoromethyl)benzenesulfonamide from 2-(trifluoromethyl)benzenesulfonyl chloride: Intermediate 1: Preparation of 2-(trifluoromethyl)benzenesulfonamide (see Scheme 3, compound XXI) To a solution of 2-(trifluoromethyl)benzenesulfonyl chloride (5 g, 20.44 mmol, 1.00 eq.) in anhydrous THF (5.00 mL) was slowly added an ethanol solution of 2 M ammonia (71 mL) under nitrogen protection and at room temperature. The reaction mixture was stirred at room temperature for 20 hours. After completion of the reaction, the solvent was removed by evaporation and the residue was redissolved in EtOAc (150 mL) and washed sequentially with saturated aqueous NH4Cl solution (50 mL) and brine (50 mL). The organic layer was dried over anhydrous MgSO4, filtered and the solvent concentrated to give pure 2-(trifluoromethyl)benzenesulfonamide as a pale yellow solid (4.6 g, 89% yield, 98.6% HPLC purity). The compound was used directly in the next reaction without further purification. 1H NMR (300MHz, CDCl3) δ: 5.0 (m, 2H), 7.6 (m, 2H), 7.8 (m, 1H), 8.3 (m, 1H). MS (ESI): m/z 224.1 [M-H]-.

References

[1] Patent: US6610853, 2003, B1
[2] Patent: WO2006/111560, 2006, A2. Location in patent: Page/Page column 48
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 9, p. 2222 - 2225

2-(Trifluoromethyl)benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Trifluoromethyl)benzenesulfonamide Suppliers

China 111 Germany 2 India 4 Italy 1 Japan 1 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 10 United States 18 Global 150

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View Lastest Price from 2-(Trifluoromethyl)benzenesulfonamide manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-24

Hebei Zhanyao Biotechnology Co. Ltd

Product: 2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-19

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2-(Trifluoromethyl)benzenesulfonamide 1869-24-5
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

1869-24-5, 2-(Trifluoromethyl)benzenesulfonamideRelated Search:

Sulfanilamide 2-(Trifluoromethyl)benzoic acid Methanesulfonamide 3-(Trifluoromethyl)benzaldehyde 2-Methylbenzotrifluoride 2-Carbomethoxybenzenesulfonamide 2-(Trifluoromethyl)benzaldehyde Benzenesulfonamide 4-(Trifluoromethyl)benzene-1-sulfonyl chloride 2-Methylbenzaldehyde o-Toluic acid 2-(TRIFLUOROMETHOXY)BENZENESULFONAMIDE alpha,alpha,alpha-Trifluoro-o-cresol 2-TRIFLUOROMETHOXY TOLUENE 2-(Trifluoromethyl)benzenesulfonyl chloride 2'-(TRIFLUOROMETHOXY)ACETOPHENONE 2-(Trifluoromethoxy)benzoic acid HYDROFLUMETHIAZIDE

2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE

2-(TRIFLUOROMETHYL)BENZENESULPHONAMIDE

(2-Trifluoromethylphenyl)-methanesulfonamide

BUTTPARK 91\08-54

BenzenesulfonaMide, 2-(trifluoroMethyl)-

2-(Trifluoromethyl)benzenesulfomide

2-(Trifluoromethyl)benzenesulfonamide ISO 9001：2015 REACH

Tritosulfuron Metabolite BH635-2

1869-24-5

C6H4CF3SO2NH2

Building Blocks

Sulfur Compounds

Sulfonamides/Sulfinamides

Organic Building Blocks

API intermediates

Organic Building Blocks

Sulfonamides/Sulfinamides

Sulfur Compounds