ChemicalBook > CAS DataBase List > ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate

ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate

Product Name
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
CAS No.
161798-01-2
Chemical Name
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
Synonyms
ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE;Febuxostat-23;Febuxostat PI-2;-4-hydroxyphenyL;Febuxostat Impurity 1;Febuxostat Impurities1;Febuxostat Impurity Z17;Febuxostat intermediate3;Ethyl 2-(3-formyl-4-hydroxyphenyl);5-carboxylato-1-ethyl-2-(3-forMyl-4-h
CBNumber
CB12128604
Molecular Formula
C14H13NO4S
Formula Weight
291.32
MOL File
161798-01-2.mol
More
Less

ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Property

Melting point:
116 °C
Boiling point:
446.7±55.0 °C(Predicted)
Density 
1.335
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
6.81±0.20(Predicted)
color 
Pale Yellow to Yellow
CAS DataBase Reference
161798-01-2(CAS DataBase Reference)
More
Less

Safety

HS Code 
2934100090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
E1394
Product name
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Packaging
5G
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
E1394
Product name
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Packaging
25G
Price
$192
Updated
2024/03/01
TRC
Product number
E918105
Product name
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Packaging
250mg
Price
$105
Updated
2021/12/16
TRC
Product number
E918105
Product name
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Packaging
500mg
Price
$185
Updated
2021/12/16
Ark Pharm
Product number
P000219190
Product name
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Purity
98%
Packaging
25g
Price
$90
Updated
2021/12/16
More
Less

ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Chemical Properties,Usage,Production

Description

Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a pharmaceutical intermediate used in the preparation of the xanthine oxidase inhibitor febuxostat, which is used in the treatment of hyperuricaemia and gout. It is also used in the synthesis of novel thiazolyl α-aminophosphonates.

Chemical Properties

Yellow or yellow powder

Uses

Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a product prepared via reaction 4-Hydroxybenzene-1-benzothiomide with ethyl-2-chloro acetoacetate. An antibacterial agent and antifungal activity against C.albicans.

ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Suppliers

Americas 1 China 338 China Hong Kong 1 Europe 1 India 22 Japan 1 United Kingdom 2 United States 13 Global 379
Jinan Lide Pharmaceutical Technology Co., Ltd.
Tel
0531-68654990 18560195202
Fax
053168654990
Email
leadgxm@leadchem.net
Country
China
ProdList
159
Advantage
58
Harway Pharma CO., LTD
Tel
0546-5612566 13793982289
Fax
0546-5180666
Email
lucy@harwaypharma.com
Country
China
ProdList
41
Advantage
58
Changzhou Xianglong Pharmaceutical Technology Co., LTD
Tel
0519-88910898 18661161657
Email
yaoxiangqiu2021@163.com
Country
China
ProdList
10066
Advantage
58
Beijing Lianben Pharm-Chemicals Tech. Co.,Ltd
Tel
010-83386559 18810831598
Fax
010-83386758
Email
sales@lianben.com
Country
China
ProdList
92
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17989
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3296
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1663
Advantage
59
Accendatech Co., LTD.
Tel
13132578992
Fax
022-83718543-802
Email
sales@accendatech.com
Country
China
ProdList
332
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9452
Advantage
58
Beijing Comparison Pharmaceutical Technology Co., Ltd
Tel
010-52878169 15701683040
Email
sales@bjcomparison.com
Country
China
ProdList
4693
Advantage
58
China Kouting Group Limited
Tel
+86 (21) 5811-6473 5811-6475
Fax
+86 (21) 6129-4103
Email
sales@koutingchina.com
Country
China
ProdList
496
Advantage
60
Emei shan Hongsheng Pharmaceutical Co., LTD
Tel
0833-6186272、6186278、6170066 18990613291
Fax
0833-5590359
Email
sales@hongshengpharm.com
Country
China
ProdList
58
Advantage
60
China Nobel Chem Co., Limited
Tel
+86(0)21 60484900
Fax
+86(0)21 60484900
Country
China
ProdList
764
Advantage
50
Shanghai Witofly Chemical Co.,Ltd
Tel
Email
sales@witofly.com
Country
China
ProdList
2867
Advantage
52
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Beijing Lianben Pharm-Chemicals Tech. Co., Ltd
Tel
+86-10-83386766
Fax
+86-10-83386758
Email
sales@lianben.com
Country
China
ProdList
91
Advantage
58
Beijing Universal Century Technology Co., Ltd.
Tel
400-8706899
Fax
400-8706899
Email
hysj_bj.com
Country
China
ProdList
3585
Advantage
55
Hubei XinyuanShun Chemical Co., Ltd.
Tel
13971561712, 13995564702, 027-50664929
Fax
027-50664927
Email
hbeixys2001@163.com
Country
China
ProdList
3123
Advantage
55
Vientiane Tianjin Hengyuan Technology Co., Ltd.
Tel
15722085254
Fax
022-26358246
Email
phytochemical@126.com
Country
China
ProdList
813
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15185
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4619
Advantage
58
Shouguang Jiasheng Chemical Co., Ltd.
Tel
0536-7971999 18232719690
Fax
0536-7971999
Email
sgjiasheng@hotmail.com
Country
China
ProdList
398
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Lihe Wuhan New Chemical Materials Co., Ltd.
Tel
027-88395709
Fax
027-88391805
Country
China
ProdList
430
Advantage
50
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5944
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Gansu HaoTian Chemical Technology Co., Ltd.
Tel
0943-6900332 17789447501
Fax
0931-8238232
Email
zhuanxiajiang@haotianpharm.com
Country
China
ProdList
206
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4901
Advantage
55
Anqing CHICO Pharmaceutical Co., Ltd.
Tel
13585175604 13585175604
Fax
+86-25-52261140
Email
sales@chicopharm.com
Country
China
ProdList
498
Advantage
65
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6508
Advantage
58
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Nanjing Vital Chemical Co., Ltd.
Tel
025-87193546 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
9030
Advantage
60
Jinan Putubio Tech Co., Ltd.
Tel
+86 (531) 8099-2215
Fax
+86 (531) 8099-2215
Email
putubio@outlook.com
Country
China
ProdList
1261
Advantage
55
Nanjing XiLang Chemical Products Co., Ltd.
Tel
025-5276156 18936048580
Email
chemxilang@163.com
Country
China
ProdList
4008
Advantage
58
Artis Biotech Co. Ltd.
Tel
19138486554 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2862
Advantage
58
More
Less

View Lastest Price from ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate manufacturers

PNP Biotech Co. Ltd
Product
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate 161798-01-2
Price
US $0.00/kg
Min. Order
25kg
Purity
98%-99%
Supply Ability
Inquiry
Release date
2022-10-18
Hebei Yanxi Chemical Co., Ltd.
Product
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 161798-01-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-07
Hebei Yanxi Chemical Co., Ltd.
Product
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 161798-01-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-10-07

161798-01-2, ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylateRelated Search:

Febuxostat Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester Febuxostat Impurity 14 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 6 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid Febuxostat Impurity 8 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate 4-HYDROXYTHIOBENZAMIDE ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate

  • ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
  • 2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester
  • Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester
  • 5-carboxylato-1-ethyl-2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-1H-1$l^{4},3-thiazol-1-yl
  • Ethyl 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate
  • 5-carboxylato-1-ethyl-2-(3-forMyl-4-h
  • ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
  • Febuxostat-23
  • Febuxostat intermediate3
  • ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazo
  • 5-Thiazolecarboxylicacid, 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-, ethyl ester
  • 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
  • Febuxostat Impurity 1
  • Febuxostat PI-2
  • Ethyl 2-(3-formyl-4-hydroxyphenyl)
  • 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylicacid ethyl ester
  • Febuxostat Impurity Z17
  • ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-
  • -4-hydroxyphenyL
  • ethyl-2-(3-formyl-4-hydroxyphenyl)-4-methyl thiozole-5-carboxylate
  • Febuxostat intermediates，Ethyl 2-(3-formyl-4-hydroxyphenyl)-4- methylthiazole-5-carboxylate
  • Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate 2-
  • Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carbox...
  • Febuxostat Impurities1
  • Ethyl 2-(3- aldehyde -4- hydroxyphenyl) -4- methylthiazole -5- carboxylate
  • Ethyl 2-(3-formyl-4-hydroxypheip)-4-methylthiazole-5-carboxylate
  • 5-Thiazolecarboxylic acid, 2-(3-formyl-4-hydroxyphenyl)-4-methyl-, ethyl ester (9CI, ACI)
  • 2-(3-formyl-4-hydroxyphenyl)-4-methyl-5-Thiazolecarboxylic acid ethyl ester (9CI ACI)
  • 2-(3-formyl-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
  • Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate（F3）
  • Ethyl 2-(3-formyl-4- hydroxyphenyl)-4-
  • 161798-01-2
  • Febuxostat intermediate
  • 161798-01-2