ChemicalBook > CAS DataBase List > DISUCCINIMIDYL SUBERATE

DISUCCINIMIDYL SUBERATE

Product Name
DISUCCINIMIDYL SUBERATE
CAS No.
68528-80-3
Chemical Name
DISUCCINIMIDYL SUBERATE
Synonyms
DSS;DSS Crosslinker;Disuccinimidyl subera;DISUCCINIMIDYL SUBERATE;DSS Disuccinimidyl subera;Disuccinimidyl subera(DSS);DISUCCINIMIDYL OCTANEDIOATE;Di(N-succinimidyl) Suberate;Bis-(N-succinimidyl)-suberate;Di(N-succinimidyl)Suberate>
CBNumber
CB1219157
Molecular Formula
C16H20N2O8
Formula Weight
368.34
MOL File
68528-80-3.mol
More
Less

DISUCCINIMIDYL SUBERATE Property

Melting point:
169-170°C
Boiling point:
513.5±60.0 °C(Predicted)
Density 
1.295 g/cm3
storage temp. 
2-8°C
solubility 
chloroform: 50 mg/mL
form 
powder
color 
White to Almost white
Water Solubility 
Insoluble in water. Soluble in chloroform: 50 mg/mL.
InChIKey
ZWIBGKZDAWNIFC-UHFFFAOYSA-N
CAS DataBase Reference
68528-80-3
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29171900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S1885
Product name
Suberic acid bis(N-hydroxysuccinimide ester)
Purity
≥95%, powder
Packaging
1g
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
S1885
Product name
Suberic acid bis(N-hydroxysuccinimide ester)
Purity
≥95%, powder
Packaging
5g
Price
$352
Updated
2024/03/01
TCI Chemical
Product number
D3895
Product name
Di(N-succinimidyl) Suberate
Purity
>98.0%(HPLC)(N)
Packaging
1g
Price
$94
Updated
2024/03/01
TCI Chemical
Product number
D3895
Product name
Di(N-succinimidyl) Suberate
Purity
>98.0%(HPLC)(N)
Packaging
5g
Price
$324
Updated
2024/03/01
Alfa Aesar
Product number
H51771
Product name
Disuccinimidyl suberate, 97%
Packaging
500mg
Price
$74.65
Updated
2024/03/01
More
Less

DISUCCINIMIDYL SUBERATE Chemical Properties,Usage,Production

Description

DSS Crosslinker is a membrane permeable, noncleavable crosslinker. The NHS ester groups are reactive toward primary amines.

Uses

Suberic acid bis(N-hydroxysuccinimide ester) has been:

  • supplemented in pierce lysis buffer used for immunoprecipitation
  • used to conjugate the oligonucleotide standards to gelatin
  • used in cross-linking of ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain) oligomers

Uses

Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.

Uses

Disuccinimidyl suberate is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm.

General Description

Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional cross-linking reagent with amine reactivity. Typically coupled to molecules containing primary amine by amide bond buffered at pH 7.5 (6.5-8.5). Suberic acid bis(N-hydroxysuccinimide ester) incorporates an 8-atom linker.

DISUCCINIMIDYL SUBERATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

DISUCCINIMIDYL SUBERATE Suppliers

Americas 1 Belgium 1 China 121 Europe 1 Germany 6 India 3 Japan 2 Switzerland 2 The Netherlands 1 United Kingdom 6 United States 35 Global 179
Suzhou Highfine Biotech Co., Ltd
Tel
0512-68311833 13962195826
Fax
0512-68417696
Email
wuhao@highfine.com
Country
China
ProdList
499
Advantage
75
Suzhouhongxiong
Tel
18051745768 18051745768
Email
Suzhouhongxiong@163.com
Country
China
ProdList
70
Advantage
58
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
979
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8418
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7191
Advantage
65
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Dalian Meilun Biotech Co., Ltd.
Tel
0411-62910999 13889544652
Email
meilunui@163.com
Country
China
ProdList
4727
Advantage
58
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5875
Advantage
58
Shanghai Xingui Biotechnology Co., Ltd.
Tel
17501653715
Email
xingui2022@126.com
Country
China
ProdList
10021
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12346
Advantage
58
Changsha Jing Kang New Material Technology Co., Ltd.
Tel
0731-85118349 18874718518
Fax
0731-85118349
Email
ma_haihong@sina.com
Country
China
ProdList
1595
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q3252066219
Fax
QQ3382968513
Email
danping@shsendpharm.com
Country
China
ProdList
3130
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Anhui kuer Bioengineering Co., Ltd
Tel
0551-65171243 13856024262
Email
kuer@kuerhuaxue.com
Country
China
ProdList
2997
Advantage
55
Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.
Tel
027-65526929 15102793023
Fax
027-65526669
Email
hbhxry@foxmail.com
Country
China
ProdList
2006
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24969
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
21085
Advantage
60
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Beijing OKA biological technology co., LTD
Tel
010-010-010-62971590 18548936886
Fax
010-62340519
Email
jack@oka-vip.com
Country
China
ProdList
6897
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
Hefei Bomei Biotechnology Co., Ltd.
Tel
13856598764
Email
531626407@qq.com
Country
China
ProdList
3007
Advantage
58
Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.
Tel
027-65526669 17771822910
Fax
027-65526669
Email
2056564811@qq.com
Country
China
ProdList
2414
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1990
Advantage
58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
Tel
+86 18953170293
Fax
+86 0531-67809011
Email
sales@sdzschem.com
Country
China
ProdList
2930
Advantage
58
Henan Alpha Chemical Co., Ltd.
Tel
0371-0371-55055611 18137792234
Fax
QQ：3002694073
Email
3002694073@qq.com
Country
China
ProdList
10566
Advantage
58
ANHUI WITOP BIOTECH CO., LTD
Tel
+8615255079626
Email
eric@witopchemical.com
Country
China
ProdList
23541
Advantage
58
More
Less

View Lastest Price from DISUCCINIMIDYL SUBERATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
DISUCCINIMIDYL SUBERATE 68528-80-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
DISUCCINIMIDYL SUBERATE 68528-80-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Career Henan Chemical Co
Product
DISUCCINIMIDYL SUBERATE 68528-80-3
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

68528-80-3, DISUCCINIMIDYL SUBERATERelated Search:

BS3 1,2-DiMyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) SodiuM Salt Suberic acid Suberate Bis(sulfosuccinimidyl) Sodium Salt Disuccinimidyl glutarate EGS Crosslinker ETHYLENE GLYCOL DISUCCINATE BIS(SULFO-N- Glycolic acid Polysuccinimide Azelaic acid dihexyl octanedioate Trimethoxyoctylsilane 4-(MALEINIMIDO)PHENYL ISOCYANATE* 4-(N-Maleimido)benzophenone 2-Maleimido acetic acid DISUCCINIMIDYL SEBACATE 4-Maleimidobenzoic acid N-Succinimidyl maleimidoacetate

  • SUBERIC ACID BIS(N-HYDROXY-SUCCINIMIDE ESTER)
  • DSS Crosslinker
  • Di(<i>N</i>-succinimidyl) Suberate
  • DISUCCINIMIDYL OCTANEDIOATE
  • DISUCCINIMIDYL SUBERATE
  • DSS
  • n-hydroxysuccinimidesubericacidester
  • Bis-(N-succinimidyl)-suberate
  • Disuccinimidyl octanedioate, Disuccinimidyl suberate (DSS)
  • N,N'-[Hexamethylenebis(carbonyloxy)]bissuccinimide
  • Octanedioic acid bis(2,5-dioxopyrrolizino)
  • Suberic acid bis(2,5-dioxopyrrolizino)
  • Suberic acid bissuccinimidyl ester
  • Di(N-succinimidyl) Suberate
  • Disuccinimidyl suberate (DSS)
  • bis(2,5-dioxopyrrolidin-1-yl) octanedioate
  • suberic acid disuccinimido ester
  • Suberic acid bis(N-succinimidyl) ester
  • Di(N-hydroxysucciniMidyl) suberate
  • Suberic Acid Di(N-succinimidyl) Ester Di(N-succinimidyl) Octanedioate Octanedioic Acid Di(N-succinimidyl) Ester DSS
  • 2,5-Pyrrolidinedione, 1,1'-[(1,8-dioxo-1,8-octanediyl)bis(oxy)]bis-
  • DSS Disuccinimidyl subera
  • Suberic acid bis(N-hydroxysuccinimide ester) >=95%, powder
  • Disuccinimidyl subera(DSS)
  • Di(N-succinimidyl)Suberate&gt
  • Disuccinimidyl subera
  • Octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl) ester
  • Di(N-succinimidyl) Octanedioate
  • Octanedioic Acid Di(N-succinimidyl) Ester
  • Suberic Acid Di(N-succinimidyl) Ester
  • Bis(2,5-dioxo-1-pyrrolidinyl) Octanedioate
  • 68528-80-3
  • Proteomics
  • Proteomics and Protein Expression
  • Protein Modification
  • Homobifunctional Cross-Linking Reagents
  • Crosslinking
  • BioChemical
  • Homobifunctional Crosslinker
  • homoXlink
  • ADC LINKER