Oxazole-2-carbaldehyde
- Product Name
- Oxazole-2-carbaldehyde
- CAS No.
- 65373-52-6
- Chemical Name
- Oxazole-2-carbaldehyde
- Synonyms
- RARECHEM AK ML 0184;OXAZOLE-2-CARBALDEHYDE;2-OXAZOLECARBOXALDEHYDE;1,3-oxazole-2-carbaldehyde;1,3-Oxazole-2-carboxaldehyde;2-Oxazolecarboxaldehyde (9CI);1,3-Oxazole-2-carboxaldehyde 97%;2-Oxazolecarboxaldehyde (9CI, ACI);Oxazole-2-carbaldehyde ISO 9001：2015 REACH
- CBNumber
- CB1247819
- Molecular Formula
- C4H3NO2
- Formula Weight
- 97.07
- MOL File
- 65373-52-6.mol
Oxazole-2-carbaldehyde Property
- Boiling point:
- 182.5±23.0 °C(Predicted)
- Density
- 1.258±0.06 g/cm3(Predicted)
- storage temp.
- -20°C, stored under nitrogen
- form
- low melting solid
- pka
- -1.86±0.10(Predicted)
- color
- Colourless
Safety
- Hazard Codes
- Xi,F
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H226Flammable liquid and vapour
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- O990988
- Product name
- Oxazole-2-carbaldehyde
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- 286292
- Product name
- 2-Oxazolecarboxaldehyde
- Packaging
- 50mg
- Price
- $368
- Updated
- 2021/12/16
- Product number
- 081680
- Product name
- 1,3-Oxazole-2-carbaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $465
- Updated
- 2021/12/16
- Product number
- OR14993
- Product name
- 1,3-Oxazole-2-carboxaldehyde
- Purity
- 96%
- Packaging
- 1g
- Price
- $314
- Updated
- 2021/12/16
- Product number
- 4H15-1-98
- Product name
- 1,3-Oxazole-2-carboxaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $346
- Updated
- 2021/12/16
Oxazole-2-carbaldehyde Chemical Properties,Usage,Production
Synthesis
288-42-6
68-12-2
65373-52-6
To a tetrahydrofuran solution of oxazole F-1 (800 mg, 11.58 mmol) was slowly added a hexane solution of 1.6 M n-butyllithium (7.2 mL, 11.58 mmol) at -78 °C. After the reaction mixture was stirred at this temperature for 1 h, a tetrahydrofuran (8 mL) solution of N,N-dimethylformamide (0.89 mmol, 11.58 mmol) was added. Subsequently, the reaction system was gradually warmed to room temperature and stirring was continued overnight. Upon completion of the reaction, the reaction was quenched with methanol, filtered through Dowex 50W x 8-200 resin (H+ type, 1:1 mass ratio of resin to oxazole F-1) and washed with methanol. The filtrates were combined and concentrated to give the crude products oxazole-2-carboxaldehyde F-2a and F-1a. The crude product was purified by column chromatography (using 100-200 mesh silica gel, eluent 2% ether/dichloromethane) to give purified oxazole-2-carboxaldehyde (900 mg, 80% yield) as a light brown liquid (Rf = 0.7, 2% ether/dichloromethane system). The product could be used directly in the subsequent reaction without further characterization.
References
[1] Patent: WO2011/35009, 2011, A1. Location in patent: Page/Page column 45-46
[2] Patent: WO2008/61109, 2008, A2. Location in patent: Page/Page column 62
[3] Patent: WO2005/102998, 2005, A1. Location in patent: Page/Page column 31
[4] Journal of Photochemistry and Photobiology A: Chemistry, 2016, vol. 316, p. 95 - 103
Oxazole-2-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
Oxazole-2-carbaldehyde Suppliers
- Tel
- --
- Fax
- --
- info@chemstep.com
- Country
- Europe
- ProdList
- 6143
- Advantage
- 51
View Lastest Price from Oxazole-2-carbaldehyde manufacturers
- Product
- Oxazole-2-carbaldehyde 65373-52-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- G/KG/T
- Release date
- 2019-12-23