ELASTATINAL
- Product Name
- ELASTATINAL
- CAS No.
- 51798-45-9
- Chemical Name
- ELASTATINAL
- Synonyms
- ELASTATINAL;AIDS-006470;Leu-co-cpd-Gln-Ala-h;ELASTATINAL USP/EP/BP;elastatinal from microbial source;N-[-N-ALPHA-CARBONYL-CPD-GLN-ALA-AL]-LEU;l-glutamamide,l-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-n-(((1-carboxy-3-m;N-[(S)-1-CARBOXYISOPENTYL]CARBAMOYL-ALPHA-[2-IMINOHEXAHYDRO-4(S)-PYRIMIDYL-(S)-GLYCYL-(S)-GLUTAMINYL-(S)-ALANINAL];Nα-[2-(2-Amino-1,4,5,6-tetrahydropyrimidin-4-yl)-N-[[(1-carboxy-3-methylbutyl)amino]carbonyl]-L-glycyl]-N1-(1-methyl-2-oxoethyl)-L-glutaminamide;L-Glutamamide, (2S)-2-(4S)-2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl-N-(1S)-1-carboxy-3-methylbutylaminocarbonylglycyl-N1-(1S)-1-methyl-2-oxoethyl-
- CBNumber
- CB1249000
- Molecular Formula
- C21H36N8O7
- Formula Weight
- 512.56
- MOL File
- 51798-45-9.mol
ELASTATINAL Property
- storage temp.
- -20°C
- solubility
- H2O: 20 mg/mL, clear, yellow
- form
- Yellow solid.
- color
- off-white
- BRN
- 873543
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
N-Bromosuccinimide Price
- Product number
- E0881
- Product name
- Elastatinal
- Purity
- microbial
- Packaging
- 5mg
- Price
- $181
- Updated
- 2024/03/01
- Product number
- E0881
- Product name
- Elastatinal
- Purity
- microbial
- Packaging
- 10mg
- Price
- $330
- Updated
- 2024/03/01
- Product number
- J61120
- Product name
- Elastatinal
- Packaging
- 5mg
- Price
- $147
- Updated
- 2023/06/20
- Product number
- J61120
- Product name
- Elastatinal
- Packaging
- 25mg
- Price
- $432
- Updated
- 2021/12/16
- Product number
- 22288
- Product name
- Elastatinal
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
ELASTATINAL Chemical Properties,Usage,Production
Description
Elastatinal is a potent inhibitor of pancreatic elastase (Ki = 240 nM) that is produced by various species of Actinomycetes. It more strongly inhibits pancreatic elastase versus the leukocyte-derived enzyme. Elastatinal reduces electrophoretic mobilities of 2A proteinases from poliovirus and human rhinovirus 14 in a dose-dependent manner, indicating substrate recognition by 2A proteinases is similar to that of pancreatic elastases. It can also inhibit elastase-like protease collagenolytic protease from C. maenas digestive glands.
Uses
Elastatinal is an elastase inhibitor.
Biochem/physiol Actions
Potent, irreversible elastase inhibitor. Elastatinal is a much stronger inhibitor of elastase from pancreas than from leucocytes.
References
1) Umezawa et al. (1973), Letter: Elastatinal, a new elastase inhibitor produced by actinomycetes; J. Antibiotics, 26 787 2) Nakajima et al. (1992), Identification of elastase as a secretory protease from cultured rat microglia; J. Neurochem., 58 1401 3) Molla et al. (1993), Inhibition of proteolytic activity of poliovirus and rhinovirus 2A proteases by elastase-specific inhibitors; J. Virol., 67 4688 4) Menendez-Arias et al. (1992), Isolation and characterization of alpha 2-macroglobulin-protease complexes from purified mouse mammary tumor virus and culture supernatants from virus-infected cell lines; J. Biol. Chem., 267 11392
ELASTATINAL Preparation Products And Raw materials
Raw materials
Preparation Products
ELASTATINAL Suppliers
- Tel
- --
- Fax
- --
- info@glenthamls.com
- Country
- United Kingdom
- ProdList
- 1429
- Advantage
- 0
- Tel
- --
- Fax
- --
- solutions@vwr.com
- Country
- United Kingdom
- ProdList
- 6548
- Advantage
- 82
View Lastest Price from ELASTATINAL manufacturers
- Product
- ELASTATINAL 51798-45-9
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-01-08