RETRORSINE
- Product Name
- RETRORSINE
- CAS No.
- 480-54-6
- Chemical Name
- RETRORSINE
- Synonyms
- Retrosine;RETRORSIN;RETRORSINE;Retrorcine;β-Longilobine;RETRORSINE(AS);BETA-LONGILOBINE;cis-retronecicacidesterofretronecine;16-dione,12,18-dihydroxy-senecionan-1;12,18-DIHYDROXYSENECIONAN-11,16-DIONE
- CBNumber
- CB1256406
- Molecular Formula
- C18H25NO6
- Formula Weight
- 351.39
- MOL File
- 480-54-6.mol
RETRORSINE Property
- Melting point:
- 208-211 °C (lit.)
- alpha
- D18 -17.6° (c = 1.99 in ethanol)
- Boiling point:
- 485.2°C (rough estimate)
- Density
- 1.32±0.1 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5100 (estimate)
- storage temp.
- 2-8°C
- pka
- 12.00±0.40(Predicted)
- form
- Solid
- color
- White to off-white
- Merck
- 13,8253
- InChIKey
- BCJMNZRQJAVDLD-VMOBWIEOSA-N
- CAS DataBase Reference
- 480-54-6
- IARC
- 3 (Vol. 10, Sup 7) 1987
- EPA Substance Registry System
- Retrorsine (480-54-6)
Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 22-36/37/39-45
- RIDADR
- 1544
- WGK Germany
- 3
- RTECS
- VH7525000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- Hazardous Substances Data
- 480-54-6(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- R0382
- Product name
- Retrorsine
- Purity
- ≥90% (HPLC)
- Packaging
- 100mg
- Price
- $261
- Updated
- 2024/03/01
- Product number
- R0382
- Product name
- Retrorsine
- Purity
- ≥90% (HPLC)
- Packaging
- 500mg
- Price
- $898
- Updated
- 2024/03/01
- Product number
- PHL89775
- Product name
- Retrorsine
- Purity
- phyproof Reference Substance
- Packaging
- 10mg
- Price
- $342
- Updated
- 2024/03/01
- Product number
- API0009902
- Product name
- RETRORSINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $573.3
- Updated
- 2021/12/16
- Product number
- 48570
- Product name
- Retrorsine
- Packaging
- 10mg
- Price
- $585
- Updated
- 2021/12/16
RETRORSINE Chemical Properties,Usage,Production
Uses
Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Definition
ChEBI: Retrorsine is a macrolide.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. hhtation data reported. When heated to decomposition it emits toxic fumes of NOx.
RETRORSINE Preparation Products And Raw materials
Raw materials
Preparation Products
RETRORSINE Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
- --
- Fax
- --
- service@applichem.de
- Country
- Germany
- ProdList
- 1607
- Advantage
- 74