RETRORSINE
- Product Name
- RETRORSINE
- CAS No.
- 480-54-6
- Chemical Name
- RETRORSINE
- Synonyms
- Retrosine;RETRORSIN;RETRORSINE;Retrorcine;β-Longilobine;RETRORSINE(AS);BETA-LONGILOBINE;cis-retronecicacidesterofretronecine;16-dione,12,18-dihydroxy-senecionan-1;12,18-DIHYDROXYSENECIONAN-11,16-DIONE
- CBNumber
- CB1256406
- Molecular Formula
- C18H25NO6
- Formula Weight
- 351.39
- MOL File
- 480-54-6.mol
RETRORSINE Property
- Melting point:
- 208-211 °C (lit.)
- alpha
- D18 -17.6° (c = 1.99 in ethanol)
- Boiling point:
- 485.2°C (rough estimate)
- Density
- 1.32±0.1 g/cm3 (20 ºC 760 Torr)
- refractive index
- 1.5100 (estimate)
- storage temp.
- 2-8°C
- pka
- 12.00±0.40(Predicted)
- Merck
- 13,8253
- InChIKey
- BCJMNZRQJAVDLD-VMOBWIEOSA-N
- CAS DataBase Reference
- 480-54-6
- IARC
- 3 (Vol. 10, Sup 7) 1987
- EPA Substance Registry System
- Retrorsine (480-54-6)
Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 22-36/37/39-45
- RIDADR
- 1544
- WGK Germany
- 3
- RTECS
- VH7525000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- Hazardous Substances Data
- 480-54-6(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- R0382
- Product name
- Retrorsine
- Purity
- ≥90% (HPLC)
- Packaging
- 100mg
- Price
- $261
- Updated
- 2024/03/01
- Product number
- R0382
- Product name
- Retrorsine
- Purity
- ≥90% (HPLC)
- Packaging
- 500mg
- Price
- $898
- Updated
- 2024/03/01
- Product number
- PHL89775
- Product name
- Retrorsine
- Purity
- phyproof Reference Substance
- Packaging
- 10mg
- Price
- $342
- Updated
- 2024/03/01
- Product number
- API0009902
- Product name
- RETRORSINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $573.3
- Updated
- 2021/12/16
- Product number
- 48570
- Product name
- Retrorsine
- Packaging
- 10mg
- Price
- $585
- Updated
- 2021/12/16
RETRORSINE Chemical Properties,Usage,Production
Uses
Retrorsine-D4 is a labelled analogue of Retrorsine (R279000). Retrorsine is a pyrrolizidine alkaloid that blocks the hepatocyte cell cycle, ultimately affecting hepatocyte proliferative capacity.
Definition
ChEBI: Retrorsine is a macrolide.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. hhtation data reported. When heated to decomposition it emits toxic fumes of NOx.