4-Hydroxytolbutamide
- Product Name
- 4-Hydroxytolbutamide
- CAS No.
- 5719-85-7
- Chemical Name
- 4-Hydroxytolbutamide
- Synonyms
- HYDROXY TOLBUTAMIDE;Tolbutamide Hydroxy;4-HYDROXYTOLBUTAMIDE;Tolbutamide Impurity 4;hydroxymethyltolbutamide;HydroxyMethylcarbutaMide;HydroxyMethylcarbutaMide Impurity;4-Hydroxytolbutamide solution ;4-Hydroxytolbutamide Solution, 100ppm;1-Butyl-3-(p-hydroxyMethylphenyl)sulfonylurea
- CBNumber
- CB1258804
- Molecular Formula
- C12H18N2O4S
- Formula Weight
- 286.35
- MOL File
- 5719-85-7.mol
4-Hydroxytolbutamide Property
- Melting point:
- 100-102 °C
- Density
- 1.268±0.06 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- 2-8°C
- solubility
- ethanol: 12 mg/mL
- pka
- 4.96±0.10(Predicted)
- form
- Solid
- color
- white
Safety
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36
- Safety Statements
- 16-36/37-24/25
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 3
- HS Code
- 29350090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P235Store in a well-ventilated place. Keep cool.
N-Bromosuccinimide Price
- Product number
- UC160
- Product name
- 4-Hydroxytolbutamide
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $896
- Updated
- 2024/03/01
- Product number
- 10008520
- Product name
- 4-hydroxy Tolbutamide
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $41
- Updated
- 2024/03/01
- Product number
- 10008520
- Product name
- 4-hydroxy Tolbutamide
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- UC160
- Product name
- 4-Hydroxytolbutamide
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $1660
- Updated
- 2024/03/01
- Product number
- 10008520
- Product name
- 4-hydroxy Tolbutamide
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $286
- Updated
- 2024/03/01
4-Hydroxytolbutamide Chemical Properties,Usage,Production
Description
4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. Tolbutamide 4-hydroxylation is an often used probe reaction in the pharmaceutical industry for the characterization of CYP2C8 and CYP2C9 involvement in the metabolism of clinical drugs.
Chemical Properties
White Solid
Uses
A metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes
Uses
4-Hydroxytolbutamide has been used as a standard to assay the fungal biotransformation of tolbutamide to 4′-hydroxytolbutamide.
Definition
ChEBI: A urea that consists of 1-butylurea having a 4-hydroxymethylbenzenesulfonyl group attached at the 3-position.
4-Hydroxytolbutamide Preparation Products And Raw materials
Raw materials
Preparation Products
4-Hydroxytolbutamide Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71