VU 0364439

ChemicalBook > CAS DataBase List > VU 0364439

Product Name: VU 0364439
CAS No.: 1246086-78-1
Chemical Name: VU 0364439
Synonyms: CS-629;VU 0364439;VU 0364439 10MG;VU 0364439, >=98%;VU 0364439 USP/EP/BP;VU0364439/VU-0364439;VU 0364439;VU0364439; VU-0364439;N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide;N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide;2-PyridinecarboxaMide, N-[3-chloro-4-[[(2-chlorophenyl)aMino]sulfonyl]phenyl]-
CBNumber: CB12596591
Molecular Formula: C18H13Cl2N3O3S
Formula Weight: 422.29
MOL File: 1246086-78-1.mol

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VU 0364439 Property

Density: 1.538±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≥21.11 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form: solid
pka: 7.71±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16296
Product name: VU0364439
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 16296
Product name: VU0364439
Packaging: 5mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 16296
Product name: VU0364439
Packaging: 10mg
Price: $169
Updated: 2024/03/01

Cayman Chemical

Product number: 16296
Product name: VU0364439
Packaging: 50mg
Price: $533
Updated: 2024/03/01

Tocris

Product number: 4371
Product name: VU0364439
Purity: ≥99%(HPLC)
Packaging: 10
Price: $171
Updated: 2021/12/16

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VU 0364439 Chemical Properties,Usage,Production

Uses

VU 0364439 is a mGlu4 positive allosteric modulator (PAM) (1,2).

References

[1]. lucyna pomierny-chamioło, kinga rup, bartosz pomierny, et al. metabotropic glutamatergic receptors and their ligands in drug addiction. pharmacology & therapeutics, 2014, 142:281-305.
[2]. albert j. robichaud, darren w. engers, craig w. lindsley, et al. recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as cns therapeutics. acs chemical neuroscience, 2011, 2:433-449.
[3]. colleen m. niswender, kari a. johnson, c. david weaver, et al. discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. mol. pharmacol., 2008, 74(5):1345-1358.
[4]. darren w. engers, patrick r. gentry, richard williams, et al. synthesis and sar of novel, 4-(phenylsulfamoyl)phenylacetamide mglu4 positive allosteric modulators (pams) identified by functional high-throughput screening (hts). bioorg. med. chem. lett., 2010, 20:5175-5178.

VU 0364439 Preparation Products And Raw materials

Raw materials

Preparation Products

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VU 0364439 Suppliers

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1246086-78-1, VU 0364439Related Search:

VU 0285683 VU0155041 N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide VU0134992(hydrochloride) VU6005649 VU 591 hydrochloride VU0810464 VU0483605 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VU 6008667 (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine VU 0360172 VU 0365114 VU 0357121 VU 0360223

VU 0364439

2-PyridinecarboxaMide, N-[3-chloro-4-[[(2-chlorophenyl)aMino]sulfonyl]phenyl]-

VU0364439/VU-0364439

N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide

N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide VU0364439

CS-629

VU 0364439, >=98%

VU 0364439;VU0364439; VU-0364439

VU 0364439 10MG

N-(3-Chloro-4-(N-(2-chlorophenyl)sulfamoyl)phenyl)picolinamide

VU 0364439 USP/EP/BP

1246086-78-1

Inhibitors