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Benzoic anhydride

Product Name
Benzoic anhydride
CAS No.
93-97-0
Chemical Name
Benzoic anhydride
Synonyms
Benzoyl benzoate;Benzoyl anhydride;BENZOIC ACID ANHYDRIDE;BENZOYL OXIDE;Benzoylbenzoate;Banzoyl benzoate;Phenyl anhydride;BENZOIC ANHYDRIDE;Benzoesureanhydrid;Dibenzoic anhydride
CBNumber
CB1260942
Molecular Formula
C14H10O3
Formula Weight
226.23
MOL File
93-97-0.mol
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Benzoic anhydride Property

Melting point:
38-42 °C(lit.)
Boiling point:
360 °C
Density 
1.199 g/mL at 25 °C(lit.)
refractive index 
nD15 1.57665
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
solubility 
0.01g/l (experimental)
form 
Crystals or Crystalline Powder
color 
White to almost white
Water Solubility 
0.01 g/L
Sensitive 
Moisture Sensitive
Merck 
14,1092
BRN 
516726
InChIKey
CHIHQLCVLOXUJW-UHFFFAOYSA-N
CAS DataBase Reference
93-97-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzoic acid, anhydride(93-97-0)
EPA Substance Registry System
Benzoic anhydride (93-97-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41-36/37/38
Safety Statements 
26-39-37/39
WGK Germany 
3
10-21
TSCA 
Yes
HS Code 
29163900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
385980
Product name
Benzoic anhydride
Purity
≥95%
Packaging
100g
Price
$42.6
Updated
2024/03/01
Sigma-Aldrich
Product number
385980
Product name
Benzoic anhydride
Purity
≥95%
Packaging
500g
Price
$143
Updated
2024/03/01
TCI Chemical
Product number
B0078
Product name
Benzoic Anhydride
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$34
Updated
2024/03/01
TCI Chemical
Product number
B0078
Product name
Benzoic Anhydride
Purity
>97.0%(GC)(T)
Packaging
100g
Price
$67
Updated
2024/03/01
Alfa Aesar
Product number
A14269
Product name
Benzoic anhydride, 98%
Packaging
50g
Price
$20.65
Updated
2024/03/01
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Benzoic anhydride Chemical Properties,Usage,Production

Chemical Properties

white to almost white crystals or crystalline

Uses

Benzoic anhydride is used as a benzoylating agent in the manufacture of pharmaceuticals, dyes and intermediates. It serves as an arylation agent in the Heck reaction. It is also used to get benzoic acid through dehydration. Further, it is used to prepare furan-2-yl-phenyl-methanone, which is similar to Friedel-Crafts acylation reaction. In addition to this, it is used for the synthesis of carboxylic esters and lactones.

Uses

Benzoic Anhydride is the more active analogue of benzoic acid formed via dehydration. Benzoic Anhydride is used in the synthesis of a wide range of organic compounds including some dyes. Benzoic Anhyd ride is also used as an arylation agent in the Heck reaction.

Uses

In organic syntheses, as benzoylating agent in the manufacture of pharmaceuticals, dyes, and intermediates.

Definition

ChEBI: Benzoic anhydride is an acyclic carboxylic anhydride. It is functionally related to a benzoic acid.

Preparation

To a flask containing 14.0 gm (0.1 mole) of benzoyl chloride and equipped with a stirrer is added 40 ml of dry dioxane and it is cooled to 5°C.Then 10 ml (0.1 mole) of dry pyridine is rapidly added at 5-10°C followed by 1.0 ml (0.056 mole) of water. After stirring for 10-15 min at 0-5°C, the reaction mixture is then poured into a mixture of 75 ml of cone, hydrochloric acid, 75 gm of cracked ice, and 350 ml of water. The product is filtered, washed first for 1 min with a cold 5% solution of sodium bicarbonate and then with water. The product is dried to afford 11.0 gm (97%), m.p. 43°C (recrystallized from a mixture of ether-petroleum ether).

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 35, p. 1262, 1987 DOI: 10.1248/cpb.35.1262
Tetrahedron Letters, 26, p. 1503, 1985 DOI: 10.1016/S0040-4039(00)98536-8

General Description

Benzoic anhydride undergoes Friedel-Crafts acylation reaction with benzene over various ion-exchanged heteropoly acids to yield benzophenone.

Purification Methods

Free it from benzoic acid by washing with NaHCO3, then water, and drying. Crystallise it from *benzene (0.5mL/g) by adding just enough pet ether (b 40-60o) to cause cloudiness, then cool in ice. It can be distilled at 210-220o/20mm. [Beilstein 19 IV 550.]

Benzoic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzoic anhydride Suppliers

Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
14623
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60
Hubei Qibu New Material Technology Co., Ltd.
Tel
0715-8890696 18062324989 18062324989
Email
2284979616@qq.com
Country
China
ProdList
523
Advantage
58
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Hubei Bojie Biotechnology Co., Ltd
Tel
0713-2060728 15629612610
Email
825477621@qq.com
Country
China
ProdList
427
Advantage
58
Hubei Lingyan Biotechnology Co., Ltd
Tel
027-59304846 13297025796
Email
2331003879@qq.com
Country
China
ProdList
60
Advantage
58
ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD
Tel
0571-87997645 17371389751
Email
bd@zetchem.com
Country
China
ProdList
398
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
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View Lastest Price from Benzoic anhydride manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Benzoic anhydride 93-97-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
500kg/month
Release date
2021-05-28
Hebei Mojin Biotechnology Co., Ltd
Product
Benzoic anhydride 93-97-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-28
Xingtai Haoxun Import and Export Trade Co., Ltd.
Product
Benzoic anhydride 93-97-0
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10tons
Release date
2020-07-16

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