ChemicalBook > CAS DataBase List > 4-Amino-3-chlorophenol

4-Amino-3-chlorophenol

Product Name
4-Amino-3-chlorophenol
CAS No.
17609-80-2
Chemical Name
4-Amino-3-chlorophenol
Synonyms
4-amino-3-chloro-pheno;3-chloro-4-aminophenol;lenvaint-G;Brn 2802558;synthesis-023;synthesis-1-013;Einecs 241-583-3;Levatinib Impurity 55;4-AMINO-3-CHLOROPHENOL;lenvatinib intermediate
CBNumber
CB1266045
Molecular Formula
C6H6ClNO
Formula Weight
143.57
MOL File
17609-80-2.mol
More
Less

4-Amino-3-chlorophenol Property

Melting point:
159-160℃
Boiling point:
287.3±25.0 °C(Predicted)
Density 
1.406±0.06 g/cm3(Predicted)
RTECS 
SJ5710000
storage temp. 
2-8°C(protect from light)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Crystalline Powder
pka
9.26±0.18(Predicted)
color 
White
Stability:
Hygroscopic
InChI
InChI=1S/C6H6ClNO/c7-5-3-4(9)1-2-6(5)8/h1-3,9H,8H2
InChIKey
PNLPXABQLXSICH-UHFFFAOYSA-N
SMILES
C1(O)=CC=C(N)C(Cl)=C1
CAS DataBase Reference
17609-80-2(CAS DataBase Reference)
More
Less

Safety

HazardClass 
6.1
HS Code 
2922290090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Alfa Aesar
Product number
H66310
Product name
4-Amino-3-chlorophenol, 95%
Packaging
1g
Price
$293
Updated
2023/06/20
Alfa Aesar
Product number
H66310
Product name
4-Amino-3-chlorophenol, 95%
Packaging
250mg
Price
$88.9
Updated
2021/12/16
TRC
Product number
A601735
Product name
4-Amino-3-chlorophenol
Packaging
250mg
Price
$45
Updated
2021/12/16
TRC
Product number
A601735
Product name
4-Amino-3-chlorophenol
Packaging
1g
Price
$55
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-5-1F
Product name
4-Amino-3-chlorophenol
Packaging
5G
Price
$114
Updated
2021/12/16
More
Less

4-Amino-3-chlorophenol Chemical Properties,Usage,Production

Chemical Properties

Light yellow solid

Uses

4-Amino-3-Chlorophenol acts as a synthetic reagent for the preparation of Benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer''s disease treatment.

Application

The 4-amino-3-chlorophenol is a crucial intermediate for preparing a tyrosine kinase inhibitor, tivozanib, and a late liver cancer drug, lenvatinib. As a crucial pharmaceutical chemical intermediate, 4-amino-3-chlorophenol is widely applied to the design and synthesis of medicaments for resisting tumors, cardiovascular diseases, neurological diseases, and the like.

Synthesis

Starting from o-chloronitrobenzene with introducing hydroxyl groups in the presence of strong acids and molybdenum salts as catalysts could synthesize 4-amino-3-chlorophenol. Besides, using m-chlorophenol as a starting material and introducing hydroxyl on a benzene ring through diazotization and coupling also could synthesize 4-Amino-3-chlorophenol.

4-Amino-3-chlorophenol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Amino-3-chlorophenol Suppliers

China 314 Germany 1 India 6 United Kingdom 6 United States 16 Global 343
Jinan XuanDe Chemical Co., Ltd.
Tel
0531-88803958; 18866891188
Fax
0531-82777287
Email
zhaojiangxia@shiningpharm.com
Country
China
ProdList
276
Advantage
58
iamen Keerda Bio-tech Co., LTD
Tel
18060983084
Email
753760940@qq.com
Country
China
ProdList
32
Advantage
58
Nanjing Yiyuan
Tel
18061915908
Email
945992976@qq.com
Country
China
ProdList
25
Advantage
58
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2988
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9512
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2865
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
021-58170097
Email
info@topbiochem.com
Country
China
ProdList
9458
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
021-34666753 13311639313
Fax
+86-21-34979012
Email
info@shyrchem.com
Country
China
ProdList
571
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1401
Advantage
62
Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-18601685-898 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2783
Advantage
60
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Suzhou Lakestar Pharmatech Co., Ltd.
Tel
0512-63970158-603 18018108880
Fax
0512-63971078
Email
info@lakestarpharma.com
Country
China
ProdList
414
Advantage
59
Chengdu Climb Pharmaceutical Technology Co., Ltd.
Tel
028-87608726 13540107218
Fax
028-87608725
Email
sales@cdclimb.com
Country
China
ProdList
104
Advantage
58
ChongQing Purel Bio-Pharmaceutical Technology Co., Ltd.
Tel
023-89130144 18523560356
Fax
023-67534737
Email
zhyong1011@163.com
Country
China
ProdList
299
Advantage
58
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Chemfun Medical Technology(Shanghai) Co., Ltd.
Tel
021-67220633 021-54824098
Fax
+86-21-54824069
Email
chemfun@chemfun.net
Country
China
ProdList
491
Advantage
58
Jiaxing Novartis Chemical Co., Ltd.
Tel
18957373295
Fax
-
Country
China
ProdList
1580
Advantage
58
ShangHai KenEn Chemical Technology Co., Ltd.
Tel
13120367189
Fax
021-50315529
Email
mychess007@163.com
Country
China
ProdList
1994
Advantage
55
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Tianjin Anhao Biological Technology Co., Ltd.
Tel
Email
sales@ahpharmatech.com
Country
China
ProdList
5734
Advantage
55
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Changzhou Idea-Works Medical Technology Co., Ltd
Tel
0519-83879978
Email
sales@ideaworkspharm.com
Country
China
ProdList
85
Advantage
62
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Qufu Haida Tiancheng Biochemical Co., Ltd.
Tel
0537-4531868 18553729317
Email
qfhdtc@126.com
Country
China
ProdList
88
Advantage
55
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
Advantage
55
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7892
Advantage
55
Tianjing Geneston Bio-tech Co.,Ltd.
Tel
022-60131465 18920720807
Fax
022-58558581
Email
zishan_1986@163.com
Country
China
ProdList
743
Advantage
58
Anqing CHICO Pharmaceutical Co., Ltd.
Tel
13585175604
Fax
+86-25-52261140
Email
sales@chicopharm.com
Country
China
ProdList
453
Advantage
65
Nanjing Chempioneer Pharmaceutical Co., Ltd.
Tel
18068075658
Fax
-
Email
sales@chempioneer.com
Country
China
ProdList
1811
Advantage
58
Yangzhou QinYuan Pharmaceutical Co., Ltd.
Tel
0514-80939770 13773367191
Fax
0514-82664689
Email
yzqyyykj@163.com
Country
China
ProdList
242
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Shanghai Rochi Pharmaceutical Co., Ltd.
Tel
021-38751876 15000076078
Fax
021-50275764
Email
Info@rochipharma.com
Country
China
ProdList
568
Advantage
55
ShangHai Angti Biotechnology Co., Ltd.
Tel
13764913901
Fax
-
Email
info@angtibio.com
Country
China
ProdList
5037
Advantage
55
Chengdu DingDang Pharmaceutical Co., Ltd.
Tel
028-86040038 13980902949;
Fax
028-85149890
Email
market@dingdangchem.com
Country
China
ProdList
1845
Advantage
55
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
3044
Advantage
58
Jinan SanZhi Pharmaceutical Technology Co., Ltd.
Tel
15053191807
Fax
-
Email
sales_sanzhi@163.com
Country
China
ProdList
286
Advantage
55
Shandong Xuande Pharmaceutical Technology Co. LTD
Tel
18866895588
Fax
0531-82777287
Email
dingjiaying@shiningpharm.com
Country
China
ProdList
96
Advantage
55
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
More
Less

View Lastest Price from 4-Amino-3-chlorophenol manufacturers

Jinan Million Pharmaceutical Co., Ltd
Product
4-Amino-3-chlorophenol 17609-80-2
Price
US $1.00-0.50/kg
Min. Order
1kg
Purity
99%
Supply Ability
200
Release date
2023-12-11
Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-Amino-3-Chlorophenol 17609-80-2
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-16
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Amino-3-chlorophenol 17609-80-2
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500KGS
Release date
2021-07-09

17609-80-2, 4-Amino-3-chlorophenolRelated Search:

4-Amino-3-chlorophenol hydrochloride,98%,4-AMINO-3-CHLOROPHENOL HCL,4-AMINO-3-CHLOROPHENOL HYDROCHLORIDE Tris(hydroxymethyl)aminomethane 4-Aminophenol 2-Aminophenol 4-Chlorophenol 6-Aminocaproic acid 3-Chlorophenol Glycine 3-Aminophenol ALTRENOGEST CHLORTHION 1-AMINO-2-CHLORO-4-HYDROXY-9,10-ANTHRACENEDIONE 2,6-DICHLORO-4-(TRIFLUOROMETHOXY)ANILINE Lufenuron 4-METHOXY-2-CHLOROANILINE 2-Amino-6-chlorophenol-4-sulfonic acid 2-Methyl-5-amino-4-chlorophenol 5-AMINO-2-CHLOROPHENOL,3-amino-6-chloropheno

  • AMINO(4-)-3-CHLOROPHENOL
  • 4-AMINO-3-CHLOROPHENOL
  • 3-chloro-4-aminophenol
  • 4-amino-3-chloro-pheno
  • Brn 2802558
  • Einecs 241-583-3
  • Phenol, 4-amino-3-chloro-
  • lenvaint-G
  • lenvatinib intermediate
  • synthesis-023
  • synthesis-1-013
  • 4-Amino-3-chlorophenol 17609-80-2
  • Lenvatinib Intermediate V
  • Levatinib Impurity 55
  • 17609-80-2
  • 17609-80-2